(Q30404232)

21 June 2017

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title

Type 2 diabetes across generations: from pathophysiology to prevention and management (English)

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21 June 2017

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1 reference

1 reference

Christopher J Nolan

1

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Peter Damm

object named as

Peter Damm

series ordinal

2

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author name string

Marc Prentki

series ordinal

3

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21 June 2017

language of work or name

English

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publication date

24 June 2011

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21 June 2017

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21 June 2017

volume

378

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21 June 2017

issue

9786

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21 June 2017

page(s)

169-181

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Global estimates of the prevalence of diabetes for 2010 and 2030

21 June 2017

cites work

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Diabesity: therapeutic options

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Children with diabetes mellitus type 2 in Europe: an underserved population

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7 January 2021

Pregnancy in type 2 diabetes mellitus--problems & promises

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7 January 2021

Type 2 diabetes mellitus in children and adolescents is still a rare disease in Germany: a population-based assessment of the prevalence of type 2 diabetes and MODY in patients aged 0-20 years.

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7 January 2021

Type 1 and Type 2 diabetes in Asian and Pacific Islander U.S. youth: the SEARCH for Diabetes in Youth Study

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7 January 2021

Diabetes in African American youth: prevalence, incidence, and clinical characteristics: the SEARCH for Diabetes in Youth Study

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7 January 2021

Trends in the prevalence of preexisting diabetes and gestational diabetes mellitus among a racially/ethnically diverse population of pregnant women, 1999-2005.

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7 January 2021

International association of diabetes and pregnancy study groups recommendations on the diagnosis and classification of hyperglycemia in pregnancy

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7 January 2021

Pregestational diabetes and pregnancy: an Australian experience

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7 January 2021

Perinatal mortality in Type 2 diabetes mellitus

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7 January 2021

Poor pregnancy outcome in women with type 2 diabetes

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7 January 2021

The burden of mortality attributable to diabetes: realistic estimates for the year 2000

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7 January 2021

Impaired glucose tolerance, type 2 diabetes and metabolic syndrome in polycystic ovary syndrome: a systematic review and meta-analysis

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7 January 2021

Linking diabetes and cancer: a consensus on complexity

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7 January 2021

Failure of islet β‐cell compensation for insulin resistance causes type 2 diabetes: What causes non‐alcoholic fatty liver disease and non‐alcoholic steatohepatitis?

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7 January 2021

A fresh look at NASH pathogenesis. Part 1: the metabolic movers.

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7 January 2021

International Expert Committee report on the role of the A1C assay in the diagnosis of diabetes

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7 January 2021

Glycemic thresholds for diabetes-specific retinopathy: implications for diagnostic criteria for diabetes

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7 January 2021

Islet beta cell failure in type 2 diabetes

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7 January 2021

Banting Lecture. From the triumvirate to the ominous octet: a new paradigm for the treatment of type 2 diabetes mellitus

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7 January 2021

Identification and characterization of metabolically benign obesity in humans

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7 January 2021

Subcutaneous and visceral adipose tissue: their relation to the metabolic syndrome

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Is the diminished incretin effect in type 2 diabetes just an epi-phenomenon of impaired beta-cell function?

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Gluttony, sloth and the metabolic syndrome: a roadmap to lipotoxicity

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7 January 2021

The islet beta-cell: fuel responsive and vulnerable

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7 January 2021

Pathogenesis of type 2 diabetes mellitus

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7 January 2021

The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetes

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7 January 2021

Beta-cell adaptation and decompensation during the progression of diabetes.

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7 January 2021

Child health, developmental plasticity, and epigenetic programming

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Genetics of type 2 diabetes: pathophysiologic and clinical relevance

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7 January 2021

Intrauterine exposure to diabetes conveys risks for type 2 diabetes and obesity: a study of discordant sibships

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Type 2 (non-insulin-dependent) diabetes mellitus, migration and westernisation: the Tokelau Island Migrant Study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Familial risks for type 2 diabetes in Sweden

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7 January 2021

Risk of diabetes in offspring of parents with non-insulin-dependent diabetes

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7 January 2021

Increased risk of type 2 diabetes in elderly twins

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7 January 2021

Concordance rate for type II diabetes mellitus in monozygotic twins: actuarial analysis

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7 January 2021

Prevalence of Diabetes and Glucose Intolerance in 199 Offspring of Thirty-seven Conjugal Diabetic Parents

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7 January 2021

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 reference

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7 January 2021

New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk

1 reference

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7 January 2021

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

1 reference

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7 January 2021

Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge

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7 January 2021

Human genetics illuminates the paths to metabolic disease

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7 January 2021

Clinical implications of a molecular genetic classification of monogenic beta-cell diabetes

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7 January 2021

Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth

1 reference

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7 January 2021

Intrauterine diabetic environment confers risks for type 2 diabetes mellitus and obesity in the offspring, in addition to genetic susceptibility.

1 reference

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7 January 2021

Congenital Susceptibility to NIDDM: Role of Intrauterine Environment

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7 January 2021

Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring

1 reference

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7 January 2021

Association between maternal diabetes in utero and age at offspring's diagnosis of type 2 diabetes

1 reference

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7 January 2021

High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia

1 reference

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7 January 2021

Vitamin B12 and folate concentrations during pregnancy and insulin resistance in the offspring: the Pune Maternal Nutrition Study.

1 reference

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7 January 2021

Breast-feeding and type 2 diabetes in the youth of three ethnic groups: the SEARCh for diabetes in youth case-control study.

1 reference

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7 January 2021

Developmental origins of adult disease

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7 January 2021

Hypothalamic neuroendocrine circuitry is programmed by maternal obesity: interaction with postnatal nutritional environment

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7 January 2021

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome.

1 reference

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7 January 2021

Epigenetic mechanisms in the development of type 2 diabetes

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7 January 2021

Nutrition transition and its relationship to the development of obesity and related chronic diseases.

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7 January 2021

Obesity, the Metabolic Syndrome, and Type 2 Diabetes in Developing Countries: Role of Dietary Fats and Oils

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Sugar-sweetened beverages and risk of metabolic syndrome and type 2 diabetes: a meta-analysis

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

The role of iron in type 2 diabetes in humans

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7 January 2021

Vitamin D and pregnancy: An old problem revisited

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7 January 2021

Endocrine disruptors: from endocrine to metabolic disruption

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7 January 2021

Obesity, diabetes, and gut microbiota: the hygiene hypothesis expanded?

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7 January 2021

Association of television viewing with fasting and 2-h postchallenge plasma glucose levels in adults without diagnosed diabetes.

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7 January 2021

Depressive symptoms and risk of type 2 diabetes in women

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7 January 2021

Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab).

1 reference

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7 January 2021

Effects of poor and short sleep on glucose metabolism and obesity risk

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7 January 2021

Glucose sensing and the pathogenesis of obesity and type 2 diabetes

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7 January 2021

Central nervous system control of food intake and body weight

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7 January 2021

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

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7 January 2021

Toxic oligomers and islet beta cell death: guilty by association or convicted by circumstantial evidence?

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7 January 2021

Beta cell compensation for insulin resistance in Zucker fatty rats: increased lipolysis and fatty acid signalling.

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7 January 2021

Islet beta cell failure in the 60% pancreatectomised obese hyperlipidaemic Zucker fatty rat: severe dysfunction with altered glycerolipid metabolism without steatosis or a falling beta cell mass

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7 January 2021

Intrauterine growth retardation leads to the development of type 2 diabetes in the rat.

1 reference

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7 January 2021

Pancreatic beta-cell mass in European subjects with type 2 diabetes

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7 January 2021

Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes

1 reference

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7 January 2021

Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects

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7 January 2021

Reduced incretin effect in type 2 (non-insulin-dependent) diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Secretion of glucagon-like peptide-1 (GLP-1) in type 2 diabetes: what is up, what is down?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals.

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7 January 2021

Diagnosis, prediction, and natural course of HIV-1 protease-inhibitor-associated lipodystrophy, hyperlipidaemia, and diabetes mellitus: a cohort study

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7 January 2021

Lipoatrophy revisited

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Subcutaneous and visceral adipose tissue gene expression of serum adipokines that predict type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Identification and importance of brown adipose tissue in adult humans

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Genome-wide association scan meta-analysis identifies three Loci influencing adiposity and fat distribution

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

DNA methylation of genes in adipose tissue.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Preadipocytes of type 2 diabetes subjects display an intrinsic gene expression profile of decreased differentiation capacity

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Fat-induced liver insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Muscle triglyceride and insulin resistance

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Lipid and insulin infusion-induced skeletal muscle insulin resistance is likely due to metabolic feedback and not changes in IRS-1, Akt, or AS160 phosphorylation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Insulin sensitivity: modulation by nutrients and inflammation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

The role of mitochondria in the pathogenesis of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Controversies in gestational diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

A multicenter, randomized trial of treatment for mild gestational diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Effect of treatment of gestational diabetes mellitus on pregnancy outcomes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Effect of treatment of gestational diabetes mellitus on obesity in the next generation

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Gestational diabetes mellitus: clinical predictors and long-term risk of developing type 2 diabetes: a retrospective cohort study using survival analysis

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Identifying adults at high risk for diabetes and cardiovascular disease using hemoglobin A1c National Health and Nutrition Examination Survey 2005-2006.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Diet and exercise in the prevention of diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

The Indian Diabetes Prevention Programme shows that lifestyle modification and metformin prevent type 2 diabetes in Asian Indian subjects with impaired glucose tolerance (IDPP-1).

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Antidiabetic agents in subjects with mild dysglycaemia: prevention or early treatment of type 2 diabetes?

1 reference

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7 January 2021

Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Voglibose for prevention of type 2 diabetes mellitus: a randomised, double-blind trial in Japanese individuals with impaired glucose tolerance.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Reduction in weight and cardiovascular disease risk factors in individuals with type 2 diabetes: one-year results of the look AHEAD trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Adjustable gastric banding and conventional therapy for type 2 diabetes: a randomized controlled trial

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Incretin-based therapy: how do incretin mimetics and DPP-4 inhibitors fit into treatment algorithms for type 2 diabetic patients?

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

The biology of incretin hormones

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Impact of glucagon-like peptide-1 on endothelial function

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Pioglitazone acutely reduces insulin secretion and causes metabolic deceleration of the pancreatic beta-cell at submaximal glucose concentrations

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

PPAR gamma and human metabolic disease

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Insulin and rosiglitazone regulation of lipolysis and lipogenesis in human adipose tissue in vitro

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7 January 2021

A futile metabolic cycle activated in adipocytes by antidiabetic agents

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7 January 2021

Review: Peroxisome proliferator-activated receptor gamma and adipose tissue--understanding obesity-related changes in regulation of lipid and glucose metabolism

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7 January 2021

Effects of rosiglitazone on bone mineral density and remodelling parameters in Postmenopausal diabetic women: a 2-year follow-up study

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Rosiglitazone revisited: an updated meta-analysis of risk for myocardial infarction and cardiovascular mortality

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7 January 2021

Subcutaneous abdominal adipose tissue subcompartments: potential role in rosiglitazone effects

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https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Low-dose pioglitazone increases serum high molecular weight adiponectin and improves glycemic control in Japanese patients with poorly controlled type 2 diabetes.

1 reference

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7 January 2021

Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic review

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Effect of intensive insulin therapy on beta-cell function and glycaemic control in patients with newly diagnosed type 2 diabetes: a multicentre randomised parallel-group trial.

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Effects of intensive glucose lowering in type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Clinical and metabolic characteristics of patients with latent autoimmune diabetes in adults (LADA): absence of rapid beta-cell loss in patients with tight metabolic control

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

Insulin resistance is a cellular antioxidant defense mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0140-6736%2811%2960614-4

7 January 2021

10.1016/S0140-6736(11)60614-4

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DOI

1 reference

21 June 2017

1 reference