(Q48246049)

9 February 2018

title

KLF2 exerts antifibrotic and vasoprotective effects in cirrhotic rat livers: behind the molecular mechanisms of statins (English)

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9 February 2018

main subject

liver cirrhosis

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author

Juan Carlos García-Pagan

5

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9 February 2018

Jordi Gracia-Sancho

7

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9 February 2018

Jaime Bosch

6

object named as

Jaime Bosch

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9 February 2018

author name string

Giusi Marrone

1

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9 February 2018

Raquel Maeso-Díaz

2

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9 February 2018

Guillermo García-Cardena

3

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9 February 2018

Juan G Abraldes

4

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9 February 2018

language of work or name

English

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publication date

10 December 2014

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9 February 2018

published in

Gut

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9 February 2018

volume

64

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9 February 2018

issue

9

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9 February 2018

page(s)

1434-1443

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9 February 2018

Functional aspects on the pathophysiology of portal hypertension in cirrhosis

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1 reference

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Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats

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Simvastatin enhances hepatic nitric oxide production and decreases the hepatic vascular tone in patients with cirrhosis.

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Ascorbic acid improves the intrahepatic endothelial dysfunction of patients with cirrhosis and portal hypertension

21 January 2018

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Krüppel-like factors: three fingers in many pies

21 January 2018

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Endothelial expression of transcription factor Kruppel-like factor 2 and its vasoprotective target genes in the normal and cirrhotic rat liver

21 January 2018

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The transcription factor KLF2 mediates hepatic endothelial protection and paracrine endothelial-stellate cell deactivation induced by statins

21 January 2018

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Simvastatin ameliorates liver fibrosis via mediating nitric oxide synthase in rats with non-alcoholic steatohepatitis-related liver fibrosis

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KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation

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Flow cessation triggers endothelial dysfunction during organ cold storage conditions: strategies for pharmacologic intervention

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Leptin receptor blockade reduces intrahepatic vascular resistance and portal pressure in an experimental model of rat liver cirrhosis

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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A network of Krüppel-like Factors (Klfs). Klf8 is repressed by Klf3 and activated by Klf1 in vivo

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Atorvastatin lowers portal pressure in cirrhotic rats by inhibition of RhoA/Rho-kinase and activation of endothelial nitric oxide synthase

21 January 2018

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Atorvastatin attenuates hepatic fibrosis in rats after bile duct ligation via decreased turnover of hepatic stellate cells

21 January 2018

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NF-kappaB at the crossroads of life and death

21 January 2018

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Curcumin protects the rat liver from CCl4-caused injury and fibrogenesis by attenuating oxidative stress and suppressing inflammation

21 January 2018

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Rat liver sinusoidal endothelial cell phenotype is maintained by paracrine and autocrine regulation

21 January 2018

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21 January 2018

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Simvastatin activates Keap1/Nrf2 signaling in rat liver

21 January 2018

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The Nrf2 transcription factor protects from toxin-induced liver injury and fibrosis

21 January 2018

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KLF2 primes the antioxidant transcription factor Nrf2 for activation in endothelial cells

21 January 2018

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Increased oxidative stress in cirrhotic rat livers: A potential mechanism contributing to reduced nitric oxide bioavailability.

21 January 2018

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21 January 2018

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Effects of simvastatin administration on rodents with lipopolysaccharide-induced liver microvascular dysfunction

21 January 2018

1 reference

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Krüppel-like factor 2 promotes liver steatosis through upregulation of CD36.

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308338

Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1136%2FGUTJNL-2014-308338

10.1136/GUTJNL-2014-308338

21 January 2018

Identifiers

DOI

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9 February 2018

1 reference

9 February 2018