(Q48248963)

9 February 2018

title

IGF-I-induced oligodendrocyte progenitor proliferation requires PI3K/Akt, MEK/ERK, and Src-like tyrosine kinases (English)

1 reference

9 February 2018

1 reference

Qiao-Ling Cui

1

1 reference

9 February 2018

Guillermina Almazan

series ordinal

2

1 reference

9 February 2018

language of work or name

English

0 references

publication date

1 March 2007

1 reference

9 February 2018

Journal of Neurochemistry

published in

1 reference

9 February 2018

volume

100

1 reference

9 February 2018

issue

6

1 reference

9 February 2018

page(s)

1480-1493

1 reference

9 February 2018

Structure and function of the type 1 insulin-like growth factor receptor.

cites work

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Cell death and control of cell survival in the oligodendrocyte lineage

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Proliferative defect and embryonic lethality in mice homozygous for a deletion in the p110alpha subunit of phosphoinositide 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Early embryonic lethality in mice deficient in the p110beta catalytic subunit of PI 3-kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Signaling by insulin-like growth factor 1 in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor (IGF)-1 suppresses oligodendrocyte caspase-3 activation and increases glial proliferation after ischemia in near-term fetal sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I increases brain growth and central nervous system myelination in transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Phosphorylation of Ser-241 is essential for the activity of 3-phosphoinositide-dependent protein kinase-1: identification of five sites of phosphorylation in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Regulation of Akt/PKB activation by tyrosine phosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Minireview: Integral Membrane Proteins that Function Coordinately with the Insulin-Like Growth Factor I Receptor to Regulate Intracellular Signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

The inhibition of glycogen synthase kinase-3 by insulin or insulin-like growth factor 1 in the rat skeletal muscle cell line L6 is blocked by wortmannin, but not by rapamycin: evidence that wortmannin blocks activation of the mitogen-activated prote

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Inhibition of Src-like kinases reveals Akt-dependent and -independent pathways in insulin-like growth factor I-mediated oligodendrocyte progenitor survival

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Role of phosphatidylinositol 3,4,5-trisphosphate in regulating the activity and localization of 3-phosphoinositide-dependent protein kinase-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Mutant mouse models of insulin-like growth factor actions in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Cloning of a human phosphoinositide 3-kinase with a C2 domain that displays reduced sensitivity to the inhibitor wortmannin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

The insulin-like growth factor axis in cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Role for Akt3/protein kinase Bgamma in attainment of normal brain size

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Monoclonal antibody to a plasma membrane antigen of neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

IGF-I and FGF-2 coordinately enhance cyclin D1 and cyclin E-cdk2 association and activity to promote G1 progression in oligodendrocyte progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Akt mediates cytoprotection of endothelial cells by vascular endothelial growth factor in an anchorage-dependent manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor-1 reduces postischemic white matter injury in fetal sheep.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Centaurin-alpha1 is a phosphatidylinositol 3-kinase-dependent activator of ERK1/2 mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Characterization of PDK2 activity against protein kinase B gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

IGF-I synergizes with FGF-2 to stimulate oligodendrocyte progenitor entry into the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Novel PI analogues selectively block activation of the pro-survival serine/threonine kinase Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Constitutive phosphorylation of the receptor for insulinlike growth factor I in cells transformed by the src oncogene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

IGF-I elicits growth of human intestinal smooth muscle cells by activation of PI3K, PDK-1, and p70S6 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Nuclear retention of MBP mRNAs in the quaking viable mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

IGF-1 protects oligodendrocyte progenitor cells and improves neurological functions following cerebral hypoxia-ischemia in the neonatal rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

PI3K is required for insulin-stimulated but not EGF-stimulated ERK1/2 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Src family protein-tyrosine kinases alter the function of PTEN to regulate phosphatidylinositol 3-kinase/AKT cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

A2B5+ and O4+ Cycling progenitors in the adult forebrain white matter respond differentially to PDGF-AA, FGF-2, and IGF-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I (IGF-I) receptors and IGF-I action in oligodendrocytes from rat brains

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

PDGF alpha-receptor signal strength controls an RTK rheostat that integrates phosphoinositol 3'-kinase and phospholipase Cgamma pathways during oligodendrocyte maturation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I promotes cell proliferation and oligodendroglial commitment in rat glial progenitor cells developing in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I/somatomedin C: a potent inducer of oligodendrocyte development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Expression of insulin-like growth factor-binding protein messenger RNAs in developing rat oligodendrocytes and astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Glial cell line-derived neurotrophic factor-stimulated phosphatidylinositol 3-kinase and Akt activities exert opposing effects on the ERK pathway: importance for the rescue of neuroectodermic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I stimulates oligodendrocyte development and myelination in rat brain aggregate cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I, but not neurotrophin-3, sustains Akt activation and provides long-term protection of immature oligodendrocytes from glutamate-mediated apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Regulation of the ABC kinases by phosphorylation: protein kinase C as a paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

PKA phosphorylation of Src mediates Rap1 activation in NGF and cAMP signaling in PC12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Effects of insulin and insulin-like growth factor (IGF-I) on oligodendrocyte-enriched glial cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Intracellular events mediating insulin-like growth factor I-induced oligodendrocyte development: modulation by cyclic AMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Identification of tyrosine phosphorylation sites on 3-phosphoinositide-dependent protein kinase-1 and their role in regulating kinase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Src phosphorylates the insulin-like growth factor type I receptor on the autophosphorylation sites. Requirement for transformation by src.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Regulation of Raf by Akt controls growth and differentiation in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Differentiation stage-specific inhibition of the Raf-MEK-ERK pathway by Akt.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Evidence for the presence of specific receptors for insulin-like growth factors 1 (IGF-1) and 2 (IGF-2) and insulin throughout the adult human brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

The Src-family tyrosine kinase inhibitor PP1 interferes with the activation of ribosomal protein S6 kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

PKB/Akt mediates cell-cycle progression by phosphorylation of p27(Kip1) at threonine 157 and modulation of its cellular localization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Monoclonal antibodies (O1 to O4) to oligodendrocyte cell surfaces: an immunocytological study in the central nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Pyk2- and Src-dependent tyrosine phosphorylation of PDK1 regulates focal adhesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Cellular functions regulated by Src family kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Cellular signaling: pivoting around PDK-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Essential role of protein kinase B gamma (PKB gamma/Akt3) in postnatal brain development but not in glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

The PI3K-PDK1 connection: more than just a road to PKB

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Synthesis and function of 3-phosphorylated inositol lipids

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Mouse p170 is a novel phosphatidylinositol 3-kinase containing a C2 domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Developmental regulation of the rat insulin-like growth factor I receptor gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Calcium-induced human keratinocyte differentiation requires src- and fyn-mediated phosphatidylinositol 3-kinase-dependent activation of phospholipase C-gamma1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Physiological functions of protein kinase B/Akt

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor I treatment reduces demyelination and up-regulates gene expression of myelin-related proteins in experimental autoimmune encephalomyelitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor-I (IGF-I) protects myelination from undernutritional insult: studies of transgenic mice overexpressing IGF-I in brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Role of phosphoinositide 3-kinase and endocytosis in nerve growth factor-induced extracellular signal-regulated kinase activation via Ras and Rap1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Insulin-like growth factor-1 provides protection against psychosine-induced apoptosis in cultured mouse oligodendrocyte progenitor cells using primarily the PI3K/Akt pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

Phosphorylation and regulation of Raf by Akt (protein kinase B)

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

The effect of insulin-like growth factors on brain myelination and their potential therapeutic application in myelination disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2006.04329.X

10.1111/J.1471-4159.2006.04329.X

21 January 2018

Identifiers

DOI

1 reference

9 February 2018

1 reference

9 February 2018