(Q48277126)

10 February 2018

title

Mutual dependence of the MRTF-SRF and YAP-TEAD pathways in cancer-associated fibroblasts is indirect and mediated by cytoskeletal dynamics (English)

1 reference

10 February 2018

cancer-associated fibroblast

main subject

cytoskeleton

0 references

1 reference

3

1 reference

10 February 2018

Francesco Gualdrini

object named as

Francesco Gualdrini

series ordinal

2

0 references

author name string

Charles T Foster

series ordinal

1

1 reference

10 February 2018

publication date

9 January 2018

1 reference

10 February 2018

published in

Genes & Development

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10 February 2018

volume

31

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10 February 2018

issue

23-24

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10 February 2018

page(s)

2361-2375

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10 February 2018

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5795783/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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MRTF potentiates TEAD-YAP transcriptional activity causing metastasis.

22 May 2018

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SRF Co-factors Control the Balance between Cell Proliferation and Contractility

22 May 2018

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22 May 2018

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Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3

22 May 2018

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YAP Nuclear Localization in the Absence of Cell-Cell Contact Is Mediated by a Filamentous Actin-dependent, Myosin II- and Phospho-YAP-independent Pathway during Extracellular Matrix Mechanosensing

22 May 2018

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Cdc42EP3/BORG2 and Septin Network Enables Mechano-transduction and the Emergence of Cancer-Associated Fibroblasts

22 May 2018

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Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction

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Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

22 May 2018

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YAP1 Exerts Its Transcriptional Control via TEAD-Mediated Activation of Enhancers

22 May 2018

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Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

22 May 2018

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Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway

22 May 2018

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Matrix Rigidity Mediates TGFβ1-Induced Epithelial-Myofibroblast Transition by Controlling Cytoskeletal Organization and MRTF-A Localization.

22 May 2018

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Matrix elasticity regulates lamin-A,C phosphorylation and turnover with feedback to actomyosin.

22 May 2018

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Rho-actin signaling to the MRTF coactivators dominates the immediate transcriptional response to serum in fibroblasts

22 May 2018

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Integrin αv in the mechanical response of osteoblast lineage cells

22 May 2018

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Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts

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Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts.

22 May 2018

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The Hippo pathway member Yap plays a key role in influencing fate decisions in muscle satellite cells

22 May 2018

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Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling

22 May 2018

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Matrix stiffness-induced myofibroblast differentiation is mediated by intrinsic mechanotransduction

22 May 2018

1 reference

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Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

22 May 2018

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The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

22 May 2018

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Hippo pathway regulation by cell morphology and stress fibers.

22 May 2018

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Role of YAP/TAZ in mechanotransduction

22 May 2018

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Balancing forces: architectural control of mechanotransduction

22 May 2018

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Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin

22 May 2018

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Integrins and extracellular matrix in mechanotransduction

22 May 2018

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Mammary gland ECM remodeling, stiffness, and mechanosignaling in normal development and tumor progression

22 May 2018

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22 May 2018

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Matrix crosslinking forces tumor progression by enhancing integrin signaling

22 May 2018

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Transcriptional output of the Salvador/warts/hippo pathway is controlled in distinct fashions in Drosophila melanogaster and mammalian cell lines

22 May 2018

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Growth factors, matrices, and forces combine and control stem cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

TEAD mediates YAP-dependent gene induction and growth control

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Feedback regulation of opposing enzymes generates robust, all-or-none bistable responses

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Fibroblast-led collective invasion of carcinoma cells with differing roles for RhoGTPases in leading and following cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Elucidation of a universal size-control mechanism in Drosophila and mammals

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Nuclear actin regulates dynamic subcellular localization and activity of the SRF cofactor MAL.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Force activates smooth muscle alpha-actin promoter activity through the Rho signaling pathway

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Substrate competition as a source of ultrasensitivity in the inactivation of Wee1.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Matrix elasticity directs stem cell lineage specification

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

MAL and ternary complex factor use different mechanisms to contact a common surface on the serum response factor DNA-binding domain.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Tensional homeostasis and the malignant phenotype

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Megakaryoblastic leukemia 1, a potent transcriptional coactivator for serum response factor (SRF), is required for serum induction of SRF target genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Actin dynamics control SRF activity by regulation of its coactivator MAL

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Signal-regulated activation of serum response factor is mediated by changes in actin dynamics

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Promoter function and structure of the growth factor-inducible immediate early gene cyr61

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Src Inhibits the Hippo Tumor Suppressor Pathway through Tyrosine Phosphorylation of Lats1.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Evidence for tension-based regulation of Drosophila MAL and SRF during invasive cell migration

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5795783

Fibroblast gene expression profile reflects the stage of tumour progression in oral squamous cell carcinoma

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29317486

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1101/GAD.304501.117

1 reference

10 February 2018

PMC publication ID

5795783

1 reference

10 February 2018

PubMed publication ID

29317486

1 reference

10 February 2018