(Q48280428)

10 February 2018

title

A bioinorganic view of Alzheimer's disease: when misplaced metal ions (re)direct the electrons to the wrong target (English)

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10 February 2018

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Peter Faller

1

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10 February 2018

Christelle Hureau

series ordinal

2

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10 February 2018

language of work or name

English

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publication date

23 November 2012

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10 February 2018

Chemistry—A European Journal

published in

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10 February 2018

volume

18

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10 February 2018

issue

50

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10 February 2018

page(s)

15910-15920

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10 February 2018

Iron-chelating backbone coupled with monoamine oxidase inhibitory moiety as novel pluripotential therapeutic agents for Alzheimer's disease: a tribute to Moussa Youdim

cites work

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Quantification of trace elements in normal human brain by inductively coupled plasma atomic emission spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Quantitative imaging of zinc, copper and lead in three distinct regions of the human brain by laser ablation inductively coupled plasma mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Imaging of copper, zinc, and other elements in thin section of human brain samples (hippocampus) by laser ablation inductively coupled plasma mass spectrometry

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

NMDA receptor activation mediates copper homeostasis in hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Methods for studying synaptosomal copper release

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Disruption of hippocampal CA3 network: effects on episodic-like memory processing in C57BL/6J mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Aβ neurotoxicity depends on interactions between copper ions, prion protein, and N-methyl-D-aspartate receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Oxidative stress in neurodegeneration: cause or consequence?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Neurodegenerative diseases and oxidative stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease--therapeutic aspects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Amyloid oligomers: formation and toxicity of Abeta oligomers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Aqueous dissolution of Alzheimer's disease Abeta amyloid deposits by biometal depletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

In vivo reduction of amyloid-beta by a mutant copper transporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Trace amounts of copper in water induce beta-amyloid plaques and learning deficits in a rabbit model of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Treatment with a copper-zinc chelator markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Substoichiometric Levels of Cu2+ Ions Accelerate the Kinetics of Fiber Formation and Promote Cell Toxicity of Amyloid-β from Alzheimer Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Copper in Alzheimer disease: too much, too little, or misplaced?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Elevated labile Cu is associated with oxidative pathology in Alzheimer disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Copper(II) binding to amyloid-beta fibrils of Alzheimer's disease reveals a picomolar affinity: stoichiometry and coordination geometry are independent of Abeta oligomeric form

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Reevaluation of copper(I) affinity for amyloid-β peptides by competition with ferrozine--an unusual copper(I) indicator

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Zinc binding to amyloid-beta: isothermal titration calorimetry and Zn competition experiments with Zn sensors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Undetectable intracellular free copper: the requirement of a copper chaperone for superoxide dismutase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Affinity gradients drive copper to cellular destinations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Amyloid beta-protein assembly and Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Rapid induction of Alzheimer A beta amyloid formation by zinc.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Abeta-mediated ROS production by Cu ions: structural insights, mechanisms and relevance to Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Electrochemical and homogeneous electron transfers to the Alzheimer amyloid-β copper complex follow a preorganization mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Vitamin E forms in Alzheimer's disease: a review of controversial and clinical experiences

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Preparation and study of new poly-8-hydroxyquinoline chelators for an anti-Alzheimer strategy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Metal swap between Zn7-metallothionein-3 and amyloid-beta-Cu protects against amyloid-beta toxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Two functions, one molecule: a metal-binding and a targeting moiety to combat Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Therapeutic redistribution of metal ions to treat Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Synthesis, characterization, and metal coordinating ability of multifunctional carbohydrate-containing compounds for Alzheimer's therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Combating Alzheimer's disease with multifunctional molecules designed for metal passivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Bifunctional compounds for controlling metal-mediated aggregation of the aβ42 peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

Probing oxidative stress: Small molecule fluorescent sensors of metal ions, reactive oxygen species, and thiols

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

The Aβ Peptide of Alzheimer's Disease Directly Produces Hydrogen Peroxide through Metal Ion Reduction†

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FCHEM.201202697

21 January 2018

Identifiers

DOI

10.1002/CHEM.201202697

1 reference

10 February 2018

release_d5nqjyp4qzemzc5bxy25rgg254

Fatcat ID

0 references

1 reference

10 February 2018