(Q48304246)

10 February 2018

title

Before epilepsy unfolds: finding the epileptogenesis switch (English)

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10 February 2018

1

Annamaria Vezzani

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10 February 2018

language of work or name

English

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publication date

1 November 2012

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10 February 2018

published in

Nature Medicine

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10 February 2018

volume

18

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issue

11

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10 February 2018

page(s)

1626-1627

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10 February 2018

https://scigraph.springernature.com/pub.10.1038/nm.2982

exact match

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cites work

TSC1/TSC2 signaling in the CNS.

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mTOR: A pathogenic signaling pathway in developmental brain malformations

21 January 2018

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Finding a better drug for epilepsy: the mTOR pathway as an antiepileptogenic target

21 January 2018

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Single-cell Tsc1 knockout during corticogenesis generates tuber-like lesions and reduces seizure threshold in mice

21 January 2018

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A mouse model of tuberous sclerosis: neuronal loss of Tsc1 causes dysplastic and ectopic neurons, reduced myelination, seizure activity, and limited survival

21 January 2018

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Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice

21 January 2018

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The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy

21 January 2018

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Mapping the spatio-temporal pattern of the mammalian target of rapamycin (mTOR) activation in temporal lobe epilepsy

21 January 2018

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Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy

21 January 2018

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mTor is required for hypertrophy of Pten-deficient neuronal soma in vivo

21 January 2018

1 reference

Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy

21 January 2018

1 reference

A pulse rapamycin therapy for infantile spasms and associated cognitive decline

21 January 2018

1 reference

The interaction between early life epilepsy and autistic-like behavioral consequences: a role for the mammalian target of rapamycin (mTOR) pathway

21 January 2018

1 reference

Rapamycin reduces seizure frequency in tuberous sclerosis complex

21 January 2018

1 reference

Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis

21 January 2018

1 reference

Mammalian target of rapamycin (mTOR) inhibition: potential for antiseizure, antiepileptogenic, and epileptostatic therapy

21 January 2018

1 reference

Regulation of cell death and epileptogenesis by the mammalian target of rapamycin (mTOR): a double-edged sword?

21 January 2018

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21 January 2018

Identifiers

DOI

10.1038/NM.2982

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10 February 2018

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10 February 2018