(Q48312815)

English

Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons.

scientific article published in February 1999

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scholarly article

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

Inhibition of phosphatidylinositol 3-kinase activity elevates c-Jun N-terminal kinase activity in apoptosis of cultured cerebellar granule neurons. (English)

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

author name string

K Shimoke

1

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

S Yamagishi

2

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

M Yamada

3

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

T Ikeuchi

4

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

H Hatanaka

5

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

publication date

1 February 1999

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

number of pages

9

1 reference

based on heuristic

inferred from page(s)

Developmental Brain Research

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

112

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Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

245-253

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

2

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

Transduction of interleukin-2 antiapoptotic and proliferative signals via Akt protein kinase

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Mechanism of activation of protein kinase B by insulin and IGF-1

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Characterization of a 3-phosphoinositide-dependent protein kinase which phosphorylates and activates protein kinase Balpha

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Changes in c-Jun but not Bcl-2 family proteins in p53-dependent apoptosis of mouse cerebellar granule neurons induced by DNA damaging agent bleomycin.

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7 January 2021

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PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

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Inositol trisphosphate and calcium signalling

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Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction

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The cellular neurobiology of neuronal development: the cerebellar granule cell

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Phosphatidylinositol 3-kinase and Akt protein kinase are necessary and sufficient for the survival of nerve growth factor-dependent sympathetic neurons.

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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7 January 2021

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Induction of apoptosis in cerebellar granule neurons by low potassium: inhibition of death by insulin-like growth factor I and cAMP.

1 reference

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Insulin-like growth factor and potassium depolarization maintain neuronal survival by distinct pathways: possible involvement of PI 3-kinase in IGF-1 signaling.

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Lipid-Regulated Kinases: Some Common Themes at Last

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Regulation of neuronal survival by the serine-threonine protein kinase Akt

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Role of the Jun kinase pathway in the regulation of c-Jun expression and apoptosis in sympathetic neurons.

1 reference

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Basic fibroblast growth factor protects cerebellar neurons in primary culture from NMDA and non-NMDA receptor mediated neurotoxicity

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Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate

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Role of BCL-2 in the survival and function of developing and mature sympathetic neurons

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Activation of mitogen-activated protein kinase and p70S6 kinase is not correlated with cerebellar granule cell survival.

1 reference

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A c-Jun dominant negative mutant protects sympathetic neurons against programmed cell death

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Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill

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Developmental change in the nerve growth factor action from induction of choline acetyltransferase to promotion of cell survival in cultured basal forebrain cholinergic neurons from postnatal rats

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Activation and involvement of p38 mitogen-activated protein kinase in glutamate-induced apoptosis in rat cerebellar granule cells.

1 reference

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

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7 January 2021

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Membrane localization of phosphatidylinositol 3-kinase is sufficient to activate multiple signal-transducing kinase pathways

1 reference

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7 January 2021

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Brain-derived neurotrophic factor (BDNF) can prevent apoptosis of rat cerebellar granule neurons in culture

1 reference

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Brain-derived neurotrophic factor is a survival factor for cultured rat cerebellar granule neurons and protects them against glutamate-induced neurotoxicity

1 reference

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Autoradiographic localization and depolarization-induced release of acidic amino acids in differentiating cerebellar granule cell cultures

1 reference

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7 January 2021

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Inhibition of phosphatidylinositol 3-kinase activity blocks depolarization- and insulin-like growth factor I-mediated survival of cerebellar granule cells.

1 reference

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The molecular heterogeneity of protein kinase C and its implications for cellular regulation

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Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.

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Activation of phosphatidylinositol-3 kinase by nerve growth factor involves indirect coupling of the trk proto-oncogene with src homology 2 domains

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Cell death during development of the nervous system

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Activated phosphatidylinositol 3-kinase and Akt kinase promote survival of superior cervical neurons

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Phosphatidylinositol (3,4,5)P3 interacts with SH2 domains and modulates PI 3-kinase association with tyrosine-phosphorylated proteins

1 reference

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Involvement of phosphatidylinositol-3 kinase in prevention of low K(+)-induced apoptosis of cerebellar granule neurons.

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1 reference

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Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene

1 reference

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Activation of p44 and p42 MAP kinases is not essential for the survival of rat sympathetic neurons

1 reference

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1 reference

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based on heuristic

inferred from DOI database lookup

Phosphorylation of c-Jun is necessary for apoptosis induced by survival signal withdrawal in cerebellar granule neurons.

1 reference

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based on heuristic

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Wortmannin inactivates phosphoinositide 3-kinase by covalent modification of Lys-802, a residue involved in the phosphate transfer reaction

1 reference

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Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis

1 reference

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Insulin receptor substrate (IRS)-1 and IRS-2 are tyrosine-phosphorylated and associated with phosphatidylinositol 3-kinase in response to brain-derived neurotrophic factor in cultured cerebral cortical neurons.

1 reference

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1 reference

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Identifiers

10.1016/S0165-3806(98)00172-2

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

1 reference

Europe PubMed Central

10 February 2018

http://europepmc.org/abstract/MED/9878764

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