(Q48323832)

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Design, synthesis and in vitro study of 5,6-diaryl-1,2,4-triazine-3-ylthioacetate derivatives as COX-2 and β-amyloid aggregation inhibitors.

scientific article published on 18 February 2015

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1 March 2020

Design, synthesis and in vitro study of 5,6-diaryl-1,2,4-triazine-3-ylthioacetate derivatives as COX-2 and β-amyloid aggregation inhibitors (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690564%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

Hamid Irannejad

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1 March 2020

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1 March 2020

Sakineh Dadashpour

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1 March 2020

Tuba Tuylu Kucukkilinc

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1 March 2020

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Oya Unsal Tan

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1 March 2020

Keriman Ozadali-Sari

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Keriman Ozadali

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publication date

18 February 2015

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1 March 2020

Archiv der Pharmazie - Chemistry in Life Sciences

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1 March 2020

348

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179-187

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1 March 2020

Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Beta-amyloid precursor protein isoforms in various rat brain regions and during brain development

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Expression of COX-1 and COX-2 in a clinical model of acute inflammation

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Isoform-selective interaction of cyclooxygenase-2 with indomethacin amides studied by real-time fluorescence, inhibition kinetics, and site-directed mutagenesis

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Biological basis for the cardiovascular consequences of COX-2 inhibition: therapeutic challenges and opportunities

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors.

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Evidence that nonsteroidal anti-inflammatory drugs decrease amyloid beta 42 production by direct modulation of gamma-secretase activity

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Naproxen interferes with the assembly of Aβ oligomers implicated in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Estimation of blood-brain barrier crossing of drugs using molecular size and shape, and H-bonding descriptors.

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Thioflavine T interaction with synthetic Alzheimer's disease beta-amyloid peptides: detection of amyloid aggregation in solution

1 reference

https://api.crossref.org/works/10.1002%2FARDP.201400400

21 January 2018

Identifiers

10.1002/ARDP.201400400

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1 March 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25690564%20AND%20SRC:MED&resulttype=core&format=json

1 March 2020

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