(Q48431434)

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Circadian system functionality, hippocampal oxidative stress, and spatial memory in the APPswe/PS1dE9 transgenic model of Alzheimer disease: effects of melatonin or ramelteon.

scientific article published in August 2012

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scholarly article

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Europe PubMed Central

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8 February 2020

Circadian system functionality, hippocampal oxidative stress, and spatial memory in the APPswe/PS1dE9 transgenic model of Alzheimer disease: effects of melatonin or ramelteon (English)

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Europe PubMed Central

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8 February 2020

Alzheimer's disease

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circadian rhythm

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1 reference

based on heuristic

inferred from title

Pedro J. Camello

8

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8 February 2020

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8 February 2020

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8 February 2020

Juan Antonio Madrid

10

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8 February 2020

Russel J Reiter

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object named as

Russel J Reiter

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8 February 2020

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Beatriz Baño Otalora

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8 February 2020

Natalija Popovic

2

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8 February 2020

Juan Gambini

3

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8 February 2020

Miroljub Popovic

4

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8 February 2020

Vicent Bonet-Costa

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8 February 2020

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publication date

1 August 2012

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8 February 2020

Chronobiology International

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8 February 2020

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8 February 2020

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8 February 2020

822-834

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8 February 2020

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

1 reference

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What is sundowning?

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Molecular tools to study melatonin pathways and actions.

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Beneficial effects of melatonin in experimental models of Alzheimer disease

1 reference

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The Neuropsychological Differentiation of Patients with Very Mild Alzheimer's Disease and/or Major Depression

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Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling

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Alzheimer disease models and human neuropathology: similarities and differences

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Classification and basic pathology of Alzheimer disease

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Detailed analysis of the behavior of Lister and Wistar rats in anxiety, object recognition and object location tasks.

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Early melatonin supplementation alleviates oxidative stress in a transgenic mouse model of Alzheimer's disease

1 reference

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Acute sleep-promoting action of the melatonin agonist, ramelteon, in the rat.

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Structures of mammalian cytosolic quinone reductases.

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Progesterone to ovariectomized mice enhances cognitive performance in the spontaneous alternation, object recognition, but not placement, water maze, and contextual and cued conditioned fear tasks

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Effect of melatonin on changes in locomotor activity rhythm of Syrian hamsters injected with beta amyloid peptide 25-35 in the suprachiasmatic nuclei

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21 January 2018

Melatonin as a natural ally against oxidative stress: a physicochemical examination.

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21 January 2018

Evaluation of the protective role of melatonin on the behavioral effects of aluminum in a mouse model of Alzheimer's disease

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21 January 2018

Time course of the development of Alzheimer-like pathology in the doubly transgenic PS1+APP mouse

1 reference

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Lifespan daily locomotor activity rhythms in a mouse model of amyloid-induced neuropathology

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Aged wild-type and APP, PS1, and APP + PS1 mice present similar deficits in associative learning and synaptic plasticity independent of amyloid load.

1 reference

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21 January 2018

Amyloid, the presenilins and Alzheimer's disease

1 reference

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21 January 2018

Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats

1 reference

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21 January 2018

Cognitive correlates of Abeta deposition in male and female mice bearing amyloid precursor protein and presenilin-1 mutant transgenes

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21 January 2018

Mutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretase

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21 January 2018

Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist

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21 January 2018

Daytime sleepiness and functional impairment in Alzheimer disease

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21 January 2018

Melatonin treatment of day-night rhythm disturbances and sundowning in Alzheimer disease: an open-label pilot study using actigraphy

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21 January 2018

Alzheimer's disease: the quest to understand complexity.

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21 January 2018

Selective activation of melatonin receptors with ramelteon improves liver function and hepatic perfusion after hemorrhagic shock in rat.

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21 January 2018

Daytime sleepiness is associated with dementia and cognitive decline in older Italian adults: a population-based study.

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21 January 2018

Memantine improves spatial learning in a transgenic mouse model of Alzheimer's disease.

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21 January 2018

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease.

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21 January 2018

A new integrated variable based on thermometry, actimetry and body position (TAP) to evaluate circadian system status in humans.

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Effects of exogenous melatonin and circadian synchronization on tumor progression in melanoma-bearing C57BL6 mice.

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An assessment of the antioxidant and the antiamyloidogenic properties of melatonin: implications for Alzheimer's disease

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Melatonin's unique radical scavenging properties - roles of its functional substituents as revealed by a comparison with its structural analogs

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Ethics and methods for biological rhythm research on animals and human beings

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Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

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Reentrainment of Rat Circadian Activity Rhythms: Effects of Melatonin

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Impaired spatial learning in the APPSwe + PSEN1DeltaE9 bigenic mouse model of Alzheimer's disease.

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Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

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Circadian locomotor activity and core-body temperature rhythms in Alzheimer's disease.

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Increased melatonin 1a-receptor immunoreactivity in the hippocampus of Alzheimer's disease patients

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Reduced hippocampal MT2 melatonin receptor expression in Alzheimer's disease.

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Episodic-like memory deficits in the APPswe/PS1dE9 mouse model of Alzheimer's disease: relationships to beta-amyloid deposition and neurotransmitter abnormalities

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Chronic treatment with the α2-adrenoceptor antagonist fluparoxan prevents age-related deficits in spatial working memory in APP×PS1 transgenic mice without altering β-amyloid plaque load or astrocytosis.

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Characterization of the 3xTg-AD mouse model of Alzheimer's disease: part 1. Circadian changes

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Circadian rest-activity rhythm disturbances in Alzheimer's disease.

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Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease

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Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease

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