(Q39585259)

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Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling

scientific article published on March 2011

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scholarly article

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Europe PubMed Central

PubMed publication ID

13 September 2017

Melatonin treatment restores mitochondrial function in Alzheimer's mice: a mitochondrial protective role of melatonin membrane receptor signaling (English)

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Alzheimer's disease

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author name string

Natasa Dragicevic

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Neil Copes

2

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Gina O'Neal-Moffitt

3

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Jingji Jin

4

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Robert Buzzeo

5

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Maggie Mamcarz

6

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Jun Tan

7

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Chuanhai Cao

8

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

James M Olcese

9

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Gary W Arendash

10

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

Patrick C Bradshaw

11

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Europe PubMed Central

PubMed publication ID

13 September 2017

publication date

1 March 2011

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Europe PubMed Central

PubMed publication ID

13 September 2017

Journal of Pineal Research

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Europe PubMed Central

PubMed publication ID

13 September 2017

51

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Europe PubMed Central

PubMed publication ID

13 September 2017

1

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

75-86

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Europe PubMed Central

PubMed publication ID

13 September 2017

Mutant genes in familial Alzheimer's disease and transgenic models

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

The role of presenilins in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

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Defining molecular targets to prevent Alzheimer disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

A decade of modeling Alzheimer's disease in transgenic mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondrial dysfunction in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Energy metabolism, oxidative stress and neuronal degeneration in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Cytochrome c oxidase and mitochondrial F1F0-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Cytochrome oxidase deficiency in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondria take center stage in aging and neurodegeneration

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Lipid- and receptor-binding regions of apolipoprotein E4 fragments act in concert to cause mitochondrial dysfunction and neurotoxicity

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mortalin is regulated by APOE in hippocampus of AD patients and by human APOE in TR mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Chronic exposure to sub-lethal beta-amyloid (Abeta) inhibits the import of nuclear-encoded proteins to mitochondria in differentiated PC12 cells.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Amyloid beta-peptide promotes permeability transition pore in brain mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Kynuramines, metabolites of melatonin and other indoles: the resurrection of an almost forgotten class of biogenic amines

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin-A Highly Potent Endogenous Radical Scavenger and Electron Donor: New Aspects of the Oxidation Chemistry of this Indole Accessed in vitroa

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Reducing oxidative/nitrosative stress: a newly-discovered genre for melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Protection against cognitive deficits and markers of neurodegeneration by long-term oral administration of melatonin in a transgenic model of Alzheimer disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Inhibition of Alzheimer beta-fibrillogenesis by melatonin

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin reverses the profibrillogenic activity of apolipoprotein E4 on the Alzheimer amyloid Abeta peptide

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Abeta oligomerization

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Long-term melatonin administration protects brain mitochondria from aging.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Caloric restriction and melatonin substitution: effects on murine circadian parameters

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Reversal of biochemical and behavioral parameters of brain aging by melatonin and acetyl L-carnitine

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Dietary melatonin selectively reverses age-related changes in cortical cytokine mRNA levels, and their responses to an inflammatory stimulus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Genetic control of melatonin synthesis in the pineal gland of the mouse

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Natural melatonin 'knockdown' in C57BL/6J mice: rare mechanism truncates serotonin N-acetyltransferase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Buffer effects on ATP analysis by firefly luciferase

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Decreased MT1 and MT2 melatonin receptor expression in extrapineal tissues of the rat during physiological aging

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Loss of responsiveness to melatonin in the aging mouse suprachiasmatic nucleus

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

The neuroprotective activities of melatonin against the Alzheimer beta-protein are not mediated by melatonin membrane receptors

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin: signaling mechanisms of a pleiotropic agent

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin: a multitasking molecule

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Visualization of melatonin's multiple mitochondrial levels of protection against mitochondrial Ca(2+)-mediated permeability transition and beyond in rat brain astrocytes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin mitigates mitochondrial malfunction

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Melatonin increases the activity of the oxidative phosphorylation enzymes and the production of ATP in rat brain and liver mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Chronic melatonin therapy fails to alter amyloid burden or oxidative damage in old Tg2576 mice: implications for clinical trials

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Differential effects of melatonin on amyloid-beta peptide 25-35-induced mitochondrial dysfunction in hippocampal neurons at different stages of culture

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Identification of amyloid-beta 1-42 binding protein fragments by screening of a human brain cDNA library

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Inhibition of gamma-secretase activity reduces Abeta production, reduces oxidative stress, increases mitochondrial activity and leads to reduced vulnerability to apoptosis: Implications for the treatment of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Cytochrome c oxidase deficiency in neurons decreases both oxidative stress and amyloid formation in a mouse model of Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Potent neuroprotective properties against the Alzheimer beta-amyloid by an endogenous melatonin-related indole structure, indole-3-propionic acid

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Development of indole-3-propionic acid (OXIGON) for Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Metabolism of melatonin by cytochrome P450s in rat liver mitochondria and microsomes

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

Soluble Beta-Amyloid Leads to Mitochondrial Defects in Amyloid Precursor Protein and Tau Transgenic Mice

1 reference

https://api.crossref.org/works/10.1111%2FJ.1600-079X.2011.00864.X

21 January 2018

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10.1111/J.1600-079X.2011.00864.X

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

13 September 2017

ResearchGate publication ID

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