(Q50665343)

English

Chronic exposure to sub-lethal beta-amyloid (Abeta) inhibits the import of nuclear-encoded proteins to mitochondria in differentiated PC12 cells.

scientific article published on 13 September 2007

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Chronic exposure to sub-lethal beta-amyloid (Abeta) inhibits the import of nuclear-encoded proteins to mitochondria in differentiated PC12 cells. (English)

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

author name string

Daniel Sirk

1

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Ziping Zhu

2

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Jehangir S Wadia

3

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Natalya Shulyakova

4

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Nam Phan

5

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Jamie Fong

6

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Linda R Mills

7

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

language of work or name

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publication date

13 September 2007

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Journal of Neurochemistry

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Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

103

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

5

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

1989-2003

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

Signal-anchored proteins follow a unique insertion pathway into the outer membrane of mitochondria

1 reference

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21 January 2018

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

1 reference

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21 January 2018

Mitochondria take center stage in aging and neurodegeneration

1 reference

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21 January 2018

Uptake and pathogenic effects of amyloid beta peptide 1-42 are enhanced by integrin antagonists and blocked by NMDA receptor antagonists

1 reference

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21 January 2018

Mitochondrial signaling: the retrograde response

1 reference

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21 January 2018

Toxicity of amyloid beta peptide: tales of calcium, mitochondria, and oxidative stress

1 reference

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21 January 2018

The role of calcineurin in amyloid-beta-peptides-mediated cell death

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21 January 2018

Mitochondria dysfunction of Alzheimer's disease cybrids enhances Abeta toxicity

1 reference

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21 January 2018

Beta-amyloid inhibits integrated mitochondrial respiration and key enzyme activities

1 reference

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21 January 2018

Increased susceptibility to amyloid toxicity in familial Alzheimer's fibroblasts.

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Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

1 reference

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Defective mitochondrial protein translocation precludes normal Caenorhabditis elegans development

1 reference

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21 January 2018

Accumulation of amyloid precursor protein in the mitochondrial import channels of human Alzheimer's disease brain is associated with mitochondrial dysfunction.

1 reference

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21 January 2018

Beta-amyloid-stimulated microglia induce neuron death via synergistic stimulation of tumor necrosis factor alpha and NMDA receptors.

1 reference

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21 January 2018

Huperzine A attenuates mitochondrial dysfunction in beta-amyloid-treated PC12 cells by reducing oxygen free radicals accumulation and improving mitochondrial energy metabolism

1 reference

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21 January 2018

Intraneuronal Abeta accumulation and origin of plaques in Alzheimer's disease

1 reference

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21 January 2018

Up-regulation of calcineurin Abeta mRNA in the Alzheimer's disease brain: assessment by cDNA microarray

1 reference

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21 January 2018

Mitochondrial assembly: protein import

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04907.X

21 January 2018

Import and assembly of proteins into mitochondria of mammalian cells

1 reference

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21 January 2018

Amyloid beta-induced changes in nitric oxide production and mitochondrial activity lead to apoptosis

1 reference

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21 January 2018

A cooperative action of the ATP-dependent import motor complex and the inner membrane potential drives mitochondrial preprotein import

1 reference

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21 January 2018

Mitochondrial preprotein translocases as dynamic molecular machines

1 reference

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21 January 2018

Mixed dementia: emerging concepts and therapeutic implications

1 reference

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21 January 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease

1 reference

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21 January 2018

Differential expression of oxidative phosphorylation genes in patients with Alzheimer's disease: implications for early mitochondrial dysfunction and oxidative damage.

1 reference

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21 January 2018

Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

1 reference

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21 January 2018

A second look into the oxidant mechanisms in Alzheimer's disease

1 reference

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21 January 2018

Mitochondrial membrane potential and neuronal glutamate excitotoxicity: mortality and millivolts

1 reference

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21 January 2018

Endogenous oxidative stress in sporadic Alzheimer's disease neuronal cybrids reduces viability by increasing apoptosis through pro-death signaling pathways and is mimicked by oxidant exposure of control cybrids

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04907.X

21 January 2018

Normal human fibroblasts exposed to high- or low-dose ionizing radiation: differential effects on mitochondrial protein import and membrane potential

1 reference

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21 January 2018

Inhibition of Alzheimer's amyloid-beta peptide-induced reduction of mitochondrial membrane potential and neurotoxicity by gelsolin.

1 reference

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21 January 2018

Human deafness dystonia syndrome is caused by a defect in assembly of the DDP1/TIMM8a-TIMM13 complex

1 reference

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21 January 2018

Flow cytometry and GFP: A novel assay for measuring the import and turnover of nuclear‐encoded mitochondrial proteins in live PC12 cells

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04907.X

21 January 2018

gamma-Secretase, Notch, Abeta and Alzheimer's disease: where do the presenilins fit in?

1 reference

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21 January 2018

Import of nuclear-encoded proteins into mitochondria

1 reference

https://api.crossref.org/works/10.1111%2FJ.1471-4159.2007.04907.X

21 January 2018

Distinct mechanisms account for beta-amyloid toxicity in PC12 and differentiated PC12 neuronal cells

1 reference

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21 January 2018

A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease

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Mitochondrial abnormalities in cybrid cell models of sporadic Alzheimer's disease worsen with passage in culture

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Protein quality control in Alzheimer's disease by the ubiquitin proteasome system.

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Olanzapine and quetiapine protect PC12 cells from beta-amyloid peptide(25-35)-induced oxidative stress and the ensuing apoptosis

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21 January 2018

Nucleation-dependent polymerization is an essential component of amyloid-mediated neuronal cell death.

1 reference

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21 January 2018

Oxidative stress inhibits the mitochondrial import of preproteins and leads to their degradation

1 reference

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Calcium-regulated signaling pathways: role in amyloid beta-induced synaptic dysfunction

1 reference

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Functional analysis of human mitochondrial receptor Tom20 for protein import into mitochondria

1 reference

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Protein import into mitochondria

1 reference

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21 January 2018

Identifiers

10.1111/J.1471-4159.2007.04907.X

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

release_d2wklaupbbbp5l3tvwxr75x7jm

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https://api.fatcat.wiki/v0/release/d2wklaupbbbp5l3tvwxr75x7jm

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

17 March 2018

http://europepmc.org/abstract/MED/17868329

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