(Q48437685)

11 February 2018

title

LGR5 is a marker of poor prognosis in glioblastoma and is required for survival of brain cancer stem-like cells. (English)

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11 February 2018

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11 February 2018

Till Acker

object named as

Till Acker

7

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Christel Herold-Mende

9

object named as

Christel Herold-Mende

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11 February 2018

10

Peter Lichter

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11 February 2018

author name string

Susumu Nakata

1

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11 February 2018

Benito Campos

2

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11 February 2018

Josephine Bageritz

3

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11 February 2018

Justo Lorenzo Bermejo

4

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11 February 2018

Natalia Becker

5

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11 February 2018

Felix Engel

6

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11 February 2018

Stefan Momma

8

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11 February 2018

Violaine Goidts

12

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11 February 2018

publication date

30 August 2012

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11 February 2018

published in

Brain Pathology

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11 February 2018

volume

23

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11 February 2018

issue

1

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11 February 2018

page(s)

60-72

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11 February 2018

Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

21 January 2018

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Targeting cancer stem cells through L1CAM suppresses glioma growth

21 January 2018

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Identification of stem cells in small intestine and colon by marker gene Lgr5

21 January 2018

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Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

21 January 2018

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CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profiles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

A perivascular niche for brain tumor stem cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Differentiation therapy exerts antitumor effects on stem-like glioma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

R-spondins function as ligands of the orphan receptors LGR4 and LGR5 to regulate Wnt/beta-catenin signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Bone morphogenetic protein-7 release from endogenous neural precursor cells suppresses the tumourigenicity of stem-like glioblastoma cells.

21 January 2018

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Developmental signaling pathways in brain tumor-derived stem-like cells.

21 January 2018

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Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Comparative analysis of in vitro conditions for rat adult neural progenitor cells.

21 January 2018

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Genomic and expression profiling of glioblastoma stem cell-like spheroid cultures identifies novel tumor-relevant genes associated with survival.

21 January 2018

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Wnt signaling in development and disease

21 January 2018

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

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Molecular analysis of ex-vivo CD133+ GBM cells revealed a common invasive and angiogenic profile but different proliferative signatures among high grade gliomas.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

L1, a novel target of beta-catenin signaling, transforms cells and is expressed at the invasive front of colon cancers

21 January 2018

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Bioconductor: open software development for computational biology and bioinformatics

21 January 2018

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LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

RNAi screening in glioma stem-like cells identifies PFKFB4 as a key molecule important for cancer cell survival.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Wnt signaling, lgr5, and stem cells in the intestine and skin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Cancerous stem cells can arise from pediatric brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Wnt signaling: multiple functions in neural development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Lgr5 marks cycling, yet long-lived, hair follicle stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Hypoxic/normoxic preconditioning increases endothelial differentiation potential of human bone marrow CD133+ cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Roles of Wnt proteins in neural development and maintenance

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens

21 January 2018

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TM4 microarray software suite

21 January 2018

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Glioblastoma-derived tumorospheres identify a population of tumor stem-like cells with angiogenic potential and enhanced multidrug resistance phenotype.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2 alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Identification of human brain tumour initiating cells

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

The Intestinal Wnt/TCF Signature.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Amplified RNA synthesized from limited quantities of heterogeneous cDNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

21 January 2018

Brain tumour stem cells

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https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Association of stem cell-related markers and survival in astrocytic gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Stem cell marker CD133 affects clinical outcome in glioma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

Nestin and CD133: valuable stem cell-specific markers for determining clinical outcome of glioma patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1750-3639.2012.00618.X

10.1111/J.1750-3639.2012.00618.X

21 January 2018

Identifiers

DOI

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11 February 2018

PubMed ID

22805276

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11 February 2018