(Q48446221)

English

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma.

scientific article published on 27 November 2014

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scholarly article

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma. (English)

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

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immunohistochemistry

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based on heuristic

inferred from title

oligodendroglioma

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based on heuristic

inferred from title

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based on heuristic

inferred from title

adult oligodendroglioma

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based on heuristic

inferred from title

2

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

Volker Hovestadt

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

Michael Platten

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

Stefan M. Pfister

18

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

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object named as

Michael Weller

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Europe PubMed Central

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object named as

Wolfgang Wick

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Europe PubMed Central

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Andreas von Deimling

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object named as

Andreas von Deimling

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Europe PubMed Central

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object named as

David Capper

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Europe PubMed Central

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Christel Herold-Mende

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object named as

Christel Herold-Mende

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Europe PubMed Central

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Jens Schittenhelm

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object named as

Jens Schittenhelm

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Europe PubMed Central

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Daniel Schrimpf

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Daniel Schrimpf

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Europe PubMed Central

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Michel Mittelbronn

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object named as

Michel Mittelbronn

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Europe PubMed Central

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Andrey Korshunov

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object named as

Andrey Korshunov

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

David T. W. Jones

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object named as

David T W Jones

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

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object named as

David E Reuss

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

Christian Koelsche

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object named as

Christian Koelsche

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

Leonille Schweizer

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object named as

Leonille Schweizer

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

author name string

Benedikt Wiestler

4

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

Andreas Unterberg

14

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

publication date

27 November 2014

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Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

Acta Neuropathologica

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Europe PubMed Central

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http://europepmc.org/abstract/MED/25427834

129

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133-146

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1

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http://europepmc.org/abstract/MED/25427834

https://scigraph.springernature.com/pub.10.1007/s00401-014-1370-3

0 references

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Analysis of the IDH1 codon 132 mutation in brain tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

IDH1 mutations at residue p.R132 (IDH1(R132)) occur frequently in high-grade gliomas but not in other solid tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Monoclonal antibody specific for IDH1 R132H mutation

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Clinical utility of fluorescence in situ hybridization (FISH) in morphologically ambiguous gliomas with hybrid oligodendroglial/astrocytic features.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Identification of der(1;19)(q10;p10) in five oligodendrogliomas suggests mechanism of concurrent 1p and 19q loss.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Altered telomeres in tumors with ATRX and DAXX mutations

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Two types of chromosome 1p losses with opposite significance in gliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

A t(1;19)(q10;p10) mediates the combined deletions of 1p and 19q and predicts a better prognosis of patients with oligodendroglioma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Frequent ATRX, CIC, FUBP1 and IDH1 mutations refine the classification of malignant gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Whole-exome sequencing identifies ATRX mutation as a key molecular determinant in lower-grade glioma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewal

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying IDH1/IDH2 and TP53 mutations

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Significance of necrosis in grading of oligodendroglial neoplasms: a clinicopathologic and genetic study of newly diagnosed high-grade gliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

An integrated genomic analysis of human glioblastoma multiforme

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Oligodendroglial neoplasms: current concepts, misconceptions, and folklore

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Assessing CpG island methylator phenotype, 1p/19q codeletion, and MGMT promoter methylation from epigenome-wide data in the biomarker cohort of the NOA-04 trial

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma.

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

IDH1 and IDH2 mutations in gliomas

1 reference

https://api.crossref.org/works/10.1007%2FS00401-014-1370-3

21 January 2018

Identifiers

10.1007/S00401-014-1370-3

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

1 reference

Europe PubMed Central

11 February 2018

http://europepmc.org/abstract/MED/25427834

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