(Q48469823)

English

ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin

scientific article published on 17 June 2012

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scholarly article

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Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

ER stress, mitochondrial dysfunction and calpain/JNK activation are involved in oligodendrocyte precursor cell death by unconjugated bilirubin (English)

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

oligodendrocyte

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

Adelaide Fernandes

4

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

5

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

Andreia Barateiro

object named as

Andreia Barateiro

1

0 references

author name string

Sandra Leitão Silva

3

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

publication date

17 June 2012

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

NeuroMolecular Medicine

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

14

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

4

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

285-302

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

Oligodendrocytes: Susceptibility to injury and involvement in neurologic disease

1 reference

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21 January 2018

Protection of mature oligodendrocytes by inhibitors of caspases and calpains

1 reference

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21 January 2018

Intracellular signaling by the unfolded protein response

1 reference

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21 January 2018

Cooperation between two growth factors promotes extended self-renewal and inhibits differentiation of oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells

1 reference

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21 January 2018

Bilirubin injury to neurons and glial cells: new players, novel targets, and newer insights

1 reference

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21 January 2018

A link between hyperbilirubinemia, oxidative stress and injury to neocortical synaptosomes

1 reference

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21 January 2018

Bilirubin injury to neurons: contribution of oxidative stress and rescue by glycoursodeoxycholic acid

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21 January 2018

Cerebellar axon/myelin loss, angiogenic sprouting, and neuronal increase of vascular endothelial growth factor in a preterm infant with kernicterus

1 reference

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21 January 2018

A transcriptome analysis identifies molecular effectors of unconjugated bilirubin in human neuroblastoma SH-SY5Y cells

1 reference

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21 January 2018

Calpain: a role in cell transformation and migration

1 reference

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21 January 2018

Unconjugated bilirubin exposure impairs hippocampal long-term synaptic plasticity

1 reference

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21 January 2018

Isolation and culture of rat and mouse oligodendrocyte precursor cells.

1 reference

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21 January 2018

Mechanisms of regulation of oligodendrocyte development by p38 mitogen-activated protein kinase

1 reference

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21 January 2018

A proteomic approach to the bilirubin-induced toxicity in neuronal cells reveals a protective function of DJ-1 protein

1 reference

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21 January 2018

Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors

1 reference

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21 January 2018

Progress in periventricular leukomalacia

1 reference

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21 January 2018

Bilirubin-induced inflammatory response, glutamate release, and cell death in rat cortical astrocytes are enhanced in younger cells

1 reference

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21 January 2018

Bilirubin-induced immunostimulant effects and toxicity vary with neural cell type and maturation state

1 reference

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21 January 2018

Contribution of inflammatory processes to nerve cell toxicity by bilirubin and efficacy of potential therapeutic agents

1 reference

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21 January 2018

Cytokine production, glutamate release and cell death in rat cultured astrocytes treated with unconjugated bilirubin and LPS.

1 reference

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21 January 2018

MAPKs are key players in mediating cytokine release and cell death induced by unconjugated bilirubin in cultured rat cortical astrocytes

1 reference

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21 January 2018

Astrocyte reactivity to unconjugated bilirubin requires TNF-α and IL-1β receptor signaling pathways

1 reference

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21 January 2018

New insights into neuron-glia communication

1 reference

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21 January 2018

Isoform specific function of calpain 2 in regulating membrane protrusion

1 reference

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21 January 2018

Glutamate excitotoxicity inflicts paranodal myelin splitting and retraction

1 reference

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21 January 2018

Mitochondrial membrane permeabilization in neuronal injury

1 reference

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21 January 2018

Two proliferative stages of the oligodendrocyte lineage (A2B5+O4- and O4+GalC-) under different mitogenic control

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Bilirubin is cytotoxic to rat oligodendrocytes in vitro

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Serial brain MRI and ultrasound findings: relation to gestational age, bilirubin level, neonatal neurologic status and neurodevelopmental outcome in infants at risk of kernicterus

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

The calpain system

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Fluorescence probes used for detection of reactive oxygen species

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Unconjugated bilirubin activates and damages microglia

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Caspase-2 functions upstream of mitochondria in endoplasmic reticulum stress-induced apoptosis by bortezomib in human myeloma cells

1 reference

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21 January 2018

Bilirubin binding to myelin basic protein, histones and its inhibition in vitro of cerebellar protein synthesis

1 reference

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21 January 2018

Pioneers in the scientific study of neonatal jaundice and kernicterus

1 reference

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21 January 2018

Subcellular localization of bilirubin in rat brain after in vivo i.v. administration of [3H]bilirubin

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Oligodendroglial impact on axonal function and survival - a hypothesis

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Catecholamine-induced oligodendrocyte cell death in culture is developmentally regulated and involves free radical generation and differential activation of caspase-3.

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Role of the unfolded protein response in cell death

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Enhancing remyelination in disease--can we wrap it up?

1 reference

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21 January 2018

Partial XBP1 knockdown does not affect viability of oligodendrocyte precursor cells exposed to new models of hypoxia and ischemia in vitro

1 reference

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21 January 2018

Protein folding and the order/disorder paradox

1 reference

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21 January 2018

Hyperbilirubinemia in the newborn

1 reference

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21 January 2018

The oligodendrocyte precursor cell in health and disease

1 reference

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Stress induction of GRP78/BiP and its role in cancer.

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Advanced neuroimaging techniques: their role in the development of future fetal and neonatal neuroprotection

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21 January 2018

Endoplasmic reticulum stress in disorders of myelinating cells.

1 reference

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21 January 2018

Oligodendrocyte progenitor cells proliferate and survive in an immature state following treatment with an axolemma-enriched fraction

1 reference

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21 January 2018

Caspase-2 is localized at the Golgi complex and cleaves golgin-160 during apoptosis

1 reference

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21 January 2018

Cannabidiol induces intracellular calcium elevation and cytotoxicity in oligodendrocytes

1 reference

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21 January 2018

The ready isomerization of bilirubin IX-α in aqueous solution

1 reference

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21 January 2018

The life, death, and replacement of oligodendrocytes in the adult CNS.

1 reference

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21 January 2018

Regulation of oligodendrocyte development in the vertebrate CNS.

1 reference

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21 January 2018

Neurodevelopmental outcome of acute bilirubin encephalopathy

1 reference

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21 January 2018

Myelination and support of axonal integrity by glia

1 reference

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21 January 2018

Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain

1 reference

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21 January 2018

Elevated levels of bilirubin and long-term exposure impair human brain microvascular endothelial cell integrity

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Doxorubicin requires the sequential activation of caspase-2, protein kinase Cdelta, and c-Jun NH2-terminal kinase to induce apoptosis.

1 reference

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21 January 2018

The oligodendrocyte and its many cellular processes

1 reference

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21 January 2018

Endoplasmic reticulum-associated degradation

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Intracellular Ca2+ release through ryanodine receptors contributes to AMPA receptor-mediated mitochondrial dysfunction and ER stress in oligodendrocytes

1 reference

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21 January 2018

A trip to the ER: coping with stress

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21 January 2018

Calpain as a therapeutic target in traumatic brain injury

1 reference

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21 January 2018

Bax and calpain mediate excitotoxic oligodendrocyte death induced by activation of both AMPA and kainate receptors.

1 reference

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21 January 2018

Chronic bilirubin encephalopathy: diagnosis and outcome

1 reference

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21 January 2018

The Effects of Unconjugated Bilirubin and Related Pigments on Cultures of Rat Cerebellum*†

1 reference

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21 January 2018

Bilirubin-induced apoptosis in cultured rat neural cells is aggravated by chenodeoxycholic acid but prevented by ursodeoxycholic acid.

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Features of bilirubin-induced reactive microglia: from phagocytosis to inflammation.

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Structure and physiological function of calpains

1 reference

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21 January 2018

Caspase-2 cleavage of BID is a critical apoptotic signal downstream of endoplasmic reticulum stress

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Bilirubin selectively inhibits cytochrome c oxidase activity and induces apoptosis in immature cortical neurons: assessment of the protective effects of glycoursodeoxycholic acid.

1 reference

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21 January 2018

Selective vulnerability of rat brain regions to unconjugated bilirubin

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

Pro-inflammatory cytokines intensify the activation of NO/NOS, JNK1/2 and caspase cascades in immature neurons exposed to elevated levels of unconjugated bilirubin.

1 reference

https://api.crossref.org/works/10.1007%2FS12017-012-8187-9

21 January 2018

The critical role of JNK in the ER-mitochondrial crosstalk during apoptotic cell death

1 reference

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21 January 2018

Mitochondria, oxidative stress, and temporal lobe epilepsy

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21 January 2018

From acute ER stress to physiological roles of the Unfolded Protein Response

1 reference

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21 January 2018

Unconjugated bilirubin differentially affects the redox status of neuronal and astroglial cells

1 reference

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21 January 2018

Inhibition of Glutamate Uptake by Unconjugated Bilirubin in Cultured Cortical Rat Astrocytes: Role of Concentration and pH

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendrocyte apoptosis mediated by caspase activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MR findings in kernicterus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmentally regulated changes in c-Jun N-terminal kinase signalling determine the apoptotic response of oligodendrocyte lineage cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between serum unconjugated bilirubin levels and the autofluorescence of white blood cells in neonatal jaundice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell death in the oligodendrocyte lineage: a molecular perspective of life/death decisions in development and disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The neuropathology of kernicterus in the premature neonate: diagnostic problems

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ultrastructural aspects of bilirubin encephalopathy in cochlear nuclei of the Gunn rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Caspase-Dependent and Caspase-Independent Oligodendrocyte Death Mediated by AMPA and Kainate Receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An electron microscopic and radioautographic study on experimental kernicterus. II. Bilirubin movement within neurons and release of waste products via astroglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Global changes in gene regulation demonstrate that unconjugated bilirubin is able to upregulate and activate select components of the endoplasmic reticulum stress response pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of camptothecin, etoposide and Ca2+ on caspase-3 activity and myofibrillar disruption of chicken during postmortem ageing

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligodendroglial expression and deposition of four major myelin constituents in the myelin sheath during development. An in vivo study

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of endoplasmic reticulum stress-induced caspase activation and cell death by the overexpression of Bcl-xL or Bcl-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration in an Aβ-induced model of Alzheimer’s disease: the role of Cdk5

1 reference

https://pubmed.ncbi.nlm.nih.gov/22707385

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S12017-012-8187-9

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

11 February 2018

http://europepmc.org/abstract/MED/22707385

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