(Q48528499)

12 February 2018

title

Insights into lasalocid A ring formation by chemical chain termination in vivo (English)

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12 February 2018

author

Peter Leadlay

series ordinal

3

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12 February 2018

Manuela Tosin

object named as

Manuela Tosin

series ordinal

1

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author name string

Luke Smith

series ordinal

2

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12 February 2018

language of work or name

English

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publication date

24 October 2011

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12 February 2018

Angewandte Chemie International Edition

published in

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volume

50

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12 February 2018

issue

50

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12 February 2018

page(s)

11930-11933

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12 February 2018

The enzymology of polyether biosynthesis

cites work

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201106323

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Polyether ionophores: broad-spectrum and promising biologically active molecules for the control of drug-resistant bacteria and parasites

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Identification of selective inhibitors of cancer stem cells by high-throughput screening

21 January 2018

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Accumulation of an E,E,E-triene by the monensin-producing polyketide synthase when oxidative cyclization is blocked

21 January 2018

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A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin

21 January 2018

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Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201106323

Analysis of the biosynthetic gene cluster for the polyether antibiotic monensin in Streptomyces cinnamonensis and evidence for the role of monB and monC genes in oxidative cyclization

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201106323

Evidence that a novel thioesterase is responsible for polyketide chain release during biosynthesis of the polyether ionophore monensin.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201106323

Mechanism of thioesterase-catalyzed chain release in the biosynthesis of the polyether antibiotic nanchangmycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201106323

Analysis of specific mutants in the lasalocid gene cluster: evidence for enzymatic catalysis of a disfavoured polyether ring closure

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201106323

Identification of a gene cluster of polyether antibiotic lasalocid from Streptomyces lasaliensis.

21 January 2018

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Drug discovery for schistosomiasis: hit and lead compounds identified in a library of known drugs by medium-throughput phenotypic screening

21 January 2018

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Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis

21 January 2018

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Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A.

21 January 2018

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Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates.

21 January 2018

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https://api.crossref.org/works/10.1002%2FANIE.201106323

Synthetic chain terminators off-load intermediates from a type I polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201106323

In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FANIE.201106323

Engineering biodiversity with type II polyketide synthase genes

21 January 2018

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Engineered biosynthesis of novel polyketides: influence of a downstream enzyme on the catalytic specificity of a minimal aromatic polyketide synthase

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/ANIE.201106323

1 reference

12 February 2018

1 reference

12 February 2018