(Q48530761)

12 February 2018

title

In vivo trapping of polyketide intermediates from an assembly line synthase using malonyl carba(dethia)-N-acetyl cysteamines (English)

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12 February 2018

author

Peter Leadlay

6

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12 February 2018

Manuela Tosin

object named as

Manuela Tosin

1

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Finian J. Leeper

object named as

Finian J Leeper

5

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author name string

Yuliya Demydchuk

2

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12 February 2018

James S Parascandolo

3

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Covadonga Blasco Per

4

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12 February 2018

language of work or name

English

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publication date

8 February 2011

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12 February 2018

number of pages

3

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based on heuristic

inferred from page(s)

published in

Chemical Communications

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12 February 2018

volume

47

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12 February 2018

issue

12

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page(s)

3460-3462

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12 February 2018

Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products

cites work

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Modular organization of genes required for complex polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Functionally distinct modules operate two consecutive alpha,beta-->beta,gamma double-bond shifts in the rhizoxin polyketide assembly line

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Deconstruction of iterative multidomain polyketide synthase function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

A proteomics approach to discovering natural products and their biosynthetic pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Malonyl carba(dethia)- and malonyl oxa(dethia)-coenzyme A as tools for trapping polyketide intermediates.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Synthetic chain terminators off-load intermediates from a type I polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Complete reconstitution of a highly reducing iterative polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

In vitro reconstruction of tetronate RK-682 biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Multi-enzymatic synthesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Unnatural polyketide analogues selectively target the HER signaling pathway in human breast cancer cells

21 January 2018

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An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea

21 January 2018

1 reference

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Synthesis and biochemical analysis of complex chain-elongation intermediates for interrogation of molecular specificity in the erythromycin and pikromycin polyketide synthases

21 January 2018

1 reference

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New natural product biosynthetic chemistry discovered by genome mining

21 January 2018

1 reference

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Conserved amino acid residues correlating with ketoreductase stereospecificity in modular polyketide synthases

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

Directed mutagenesis alters the stereochemistry of catalysis by isolated ketoreductase domains from the erythromycin polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

The biochemical basis for stereochemical control in polyketide biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1039%2FC0CC05077F

A polylinker approach to reductive loop swaps in modular polyketide synthases

21 January 2018

1 reference

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Chapter 1 Introduction to Polyketide Biosynthesis

21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1039/C0CC05077F

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12 February 2018

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12 February 2018