(Q57310228)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

Introduction to polyketide biosynthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

author name string

Kira J Weissman

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

language of work or name

English

0 references

publication date

1 January 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

published in

Methods in Enzymology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

volume

459

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

page(s)

3-16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

The chalcone synthase superfamily of type III polyketide synthases

25 January 2020

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Evolving biosynthetic tangos negotiate mechanistic landscapes

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The structure of docking domains in modular polyketide synthases

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Natural products to drugs: natural product-derived compounds in clinical trials

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7 January 2021

Type I polyketide synthase requiring a discrete acyltransferase for polyketide biosynthesis

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7 January 2021

Novel intermolecular iterative mechanism for biosynthesis of mycoketide catalyzed by a bimodular polyketide synthase.

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7 January 2021

An unusually large multifunctional polypeptide in the erythromycin-producing polyketide synthase of Saccharopolyspora erythraea.

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7 January 2021

Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets

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Deconstruction of iterative multidomain polyketide synthase function.

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7 January 2021

The soil metagenome--a rich resource for the discovery of novel natural products

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7 January 2021

Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic

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7 January 2021

Modular organization of genes required for complex polyketide biosynthesis

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Assembly-line enzymology for polyketide and nonribosomal Peptide antibiotics: logic, machinery, and mechanisms.

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Antitumor antibiotics: bleomycin, enediynes, and mitomycin

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7 January 2021

Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids.

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7 January 2021

Insights into polyether biosynthesis from analysis of the nigericin biosynthetic gene cluster in Streptomyces sp. DSM4137.

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7 January 2021

Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster

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7 January 2021

Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork

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7 January 2021

The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis

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7 January 2021

Biosynthesis of polyunsaturated fatty acids by polyketide synthases.

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7 January 2021

Mutasynthesis, chemobiosynthesis, and back to semi-synthesis: combining synthetic chemistry and biosynthetic engineering for diversifying natural products

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7 January 2021

Structure and mechanism of the 6-deoxyerythronolide B synthase

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7 January 2021

Engineering of complex polyketide biosynthesis--insights from sequencing of the monensin biosynthetic gene cluster

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7 January 2021

Catalytic relationships between type I and type II iterative polyketide synthases: The Aspergillus parasiticus norsolorinic acid synthase.

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7 January 2021

Microbial genomics as a guide to drug discovery and structural elucidation: ECO-02301, a novel antifungal agent, as an example.

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7 January 2021

Production of polyunsaturated fatty acids by polyketide synthases in both prokaryotes and eukaryotes.

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7 January 2021

Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity

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7 January 2021

Structure and Partial Stereochemical Assignments for Maitotoxin, the Most Toxic and Largest Natural Non-Biopolymer

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7 January 2021

Plumbing the depths of PUFA biosynthesis: a novel polyketide synthase-like pathway from marine organisms

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7 January 2021

Exploiting the mosaic structure of trans-acyltransferase polyketide synthases for natural product discovery and pathway dissection

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7 January 2021

Developments with antarctic microorganisms: culture collections, bioactivity screening, taxonomy, PUFA production and cold-adapted enzymes

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7 January 2021

Evidence from engineered gene fusions for the repeated use of a module in a modular polyketide synthase.

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7 January 2021

A polyketide synthase-peptide synthetase gene cluster from an uncultured bacterial symbiont of Paederus beetles

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7 January 2021

Modification of post-PKS tailoring steps through combinatorial biosynthesis

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7 January 2021

Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms

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7 January 2021

Who should receive a statin these days? Lessons from recent clinical trials

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7 January 2021

Analysis of specific mutants in the lasalocid gene cluster: evidence for enzymatic catalysis of a disfavoured polyether ring closure

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7 January 2021

Polyketide biosynthesis: a millennium review

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7 January 2021

Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans

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7 January 2021

A complete gene cluster from Streptomyces nanchangensis NS3226 encoding biosynthesis of the polyether ionophore nanchangmycin

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7 January 2021

Sponge-associated microorganisms: evolution, ecology, and biotechnological potential

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7 January 2021

Biosynthesis of enediyne antitumor antibiotics

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7 January 2021

Polyunsaturated fatty acid synthesis: what will they think of next?

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7 January 2021

Erythromycin: a microbial and clinical perspective after 30 years of clinical use (1).

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7 January 2021

Mutasynthesis - uniting chemistry and genetics for drug discovery

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7 January 2021

Combinatorial biosynthesis of reduced polyketides

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7 January 2021

Mutational biosynthesis--a tool for the generation of structural diversity in the biosynthesis of antibiotics

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7 January 2021

Formation of novel secondary metabolites by bacterial multimodular assembly lines: deviations from textbook biosynthetic logic.

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7 January 2021

Recent developments towards the heterologous expression of complex bacterial natural product biosynthetic pathways.

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7 January 2021

Bacterial hosts for natural product production.

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7 January 2021

A new logic for DNA engineering using recombination in Escherichia coli

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7 January 2021

10.1016/S0076-6879(09)04601-1

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19362633%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference