(Q48532664)

12 February 2018

title

Strategy for making safer opioids bolstered. (English)

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12 February 2018

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Susruta Majumdar

1

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12 February 2018

Lakshmi A Devi

series ordinal

2

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12 February 2018

language of work or name

English

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publication date

1 January 2018

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12 February 2018

published in

Nature

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12 February 2018

volume

553

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12 February 2018

issue

7688

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12 February 2018

page(s)

286-288

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12 February 2018

https://scigraph.springernature.com/pub.10.1038/d41586-018-00045-1

exact match

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cites work

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics

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7 January 2021

Mu opioids and their receptors: evolution of a concept

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7 January 2021

Mediation of buprenorphine analgesia by a combination of traditional and truncated mu opioid receptor splice variants

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7 January 2021

Opioid ligands with mixed mu/delta opioid receptor interactions: an emerging approach to novel analgesics

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7 January 2021

Parallel Synthesis of Hexahydrodiimidazodiazepines Heterocyclic Peptidomimetics and Their in Vitro and in Vivo Activities at μ (MOR), δ (DOR), and κ (KOR) Opioid Receptors

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7 January 2021

A nontoxic pain killer designed by modeling of pathological receptor conformations

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7 January 2021

Heteromers of μ-δ opioid receptors: new pharmacology and novel therapeutic possibilities

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7 January 2021

Discovery of positive allosteric modulators and silent allosteric modulators of the μ-opioid receptor

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7 January 2021

Biased agonism: An emerging paradigm in GPCR drug discovery

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7 January 2021

Enhanced morphine analgesia in mice lacking beta-arrestin 2

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7 January 2021

Enhancement of morphine analgesia and prevention of morphine tolerance by downregulation of β-arrestin 2 with antigene RNAs in mice

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7 January 2021

Improvement of morphine-mediated analgesia by inhibition of β-arrestin2 expression in mice periaqueductal gray matter

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7 January 2021

Morphine side effects in beta-arrestin 2 knockout mice

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7 January 2021

Neoclerodane diterpenes as a novel scaffold for mu opioid receptor ligands.

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7 January 2021

A G protein-biased ligand at the μ-opioid receptor is potently analgesic with reduced gastrointestinal and respiratory dysfunction compared with morphine

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7 January 2021

Structure-based discovery of opioid analgesics with reduced side effects

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7 January 2021

Synthetic and Receptor Signaling Explorations of the Mitragyna Alkaloids: Mitragynine as an Atypical Molecular Framework for Opioid Receptor Modulators

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7 January 2021

Mitragynine/Corynantheidine Pseudoindoxyls As Opioid Analgesics with Mu Agonism and Delta Antagonism, Which Do Not Recruit β-Arrestin-2.

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7 January 2021

Effects of acute and repeated treatment with the biased mu opioid receptor agonist TRV130 (oliceridine) on measures of antinociception, gastrointestinal function, and abuse liability in rodents

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7 January 2021

10.1038/D41586-018-00045-1

Identifiers

DOI

1 reference

12 February 2018

Dimensions Publication ID

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1 reference

12 February 2018