(Q48567301)

English

A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration.

scientific article published in June 2002

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scholarly article

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10 November 2019

A long CAG repeat in the mouse Sca1 locus replicates SCA1 features and reveals the impact of protein solubility on selective neurodegeneration (English)

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10 November 2019

neurodegeneration

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12

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10 November 2019

14

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10 November 2019

J. David Sweatt

11

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10 November 2019

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Kei Watase

1

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10 November 2019

Edwin J Weeber

2

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10 November 2019

Bisong Xu

3

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Barbara Antalffy

4

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10 November 2019

Lisa Yuva-Paylor

5

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10 November 2019

Kouichi Hashimoto

6

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Masanobu Kano

7

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10 November 2019

Richard Atkinson

8

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10 November 2019

Yaling Sun

9

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10 November 2019

Dawna L Armstrong

10

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10 November 2019

Richard Paylor

13

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10 November 2019

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publication date

1 June 2002

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10 November 2019

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10 November 2019

34

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10 November 2019

6

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10 November 2019

905-919

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Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1.

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Mutation of the E6-AP ubiquitin ligase reduces nuclear inclusion frequency while accelerating polyglutamine-induced pathology in SCA1 mice.

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