(Q48585558)

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Inhibition of hypoxia inducible factor-1alpha (HIF-1alpha) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas.

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scholarly article

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

Inhibition of hypoxia inducible factor-1alpha (HIF-1alpha) decreases vascular endothelial growth factor (VEGF) secretion and tumor growth in malignant gliomas. (English)

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

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3

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

David Gillespie

object named as

David Gillespie

4

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author name string

Randy L Jensen

1

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

Brian T Ragel

2

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

publication date

13 April 2006

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

Journal of Neuro-Oncology

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

78

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

3

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

233-247

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Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

https://scigraph.springernature.com/pub.10.1007/s11060-005-9103-z

0 references

The WHO classification of tumors of the nervous system

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https://api.crossref.org/works/10.1007%2FS11060-005-9103-Z

21 January 2018

Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1

1 reference

https://api.crossref.org/works/10.1007%2FS11060-005-9103-Z

21 January 2018

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

1 reference

https://api.crossref.org/works/10.1007%2FS11060-005-9103-Z

21 January 2018

Anomalous patterns of nitroimidazole binding adjacent to necrosis in human glioma xenografts: possible role of decreased oxygen consumption

1 reference

https://api.crossref.org/works/10.1007%2FS11060-005-9103-Z

21 January 2018

Hypoxia is important in the biology and aggression of human glial brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunocytochemical mapping of the phosphatase and tensin homolog (PTEN/MMAC1) tumor suppressor protein in human gliomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flavopiridol downregulates hypoxia-mediated hypoxia-inducible factor-1alpha expression in human glioma cells by a proteasome-independent pathway: implications for in vivo therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor and its receptors in the anaplastic progression of astrocytoma, oligodendroglioma, and ependymoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

V-SRC induces expression of hypoxia-inducible factor 1 (HIF-1) and transcription of genes encoding vascular endothelial growth factor and enolase 1: involvement of HIF-1 in tumor progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Picroliv -- a natural product protects cells and regulates the gene expression during hypoxia/reoxygenation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matrigel augments xenograft transplantation of meningioma cells into athymic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of hypoxia-inducible factor 1alpha is a marker for an unfavorable prognosis in early-stage invasive cervical cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of vascular endothelial growth factor in human brain tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of angiogenesis in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor angiogenesis and therapeutics

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of HIF is necessary for tumor suppression by the von Hippel-Lindau protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of PTEN facilitates HIF-1-mediated gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p53 inhibits hypoxia-inducible factor-stimulated transcription

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ibuprofen: effect on inducible nitric oxide synthase.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal positive regulation of hypoxia-inducible factor 1alpha and insulin-like growth factor 2.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of hypoxia-inducible factor 1alpha in tumours of patients with glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Angiogenesis: how a tumor adapts to hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stabilization of wild-type p53 by hypoxia-inducible factor 1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pseudopalisades in glioblastoma are hypoxic, express extracellular matrix proteases, and are formed by an actively migrating cell population

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1-independent regulation of vascular endothelial growth factor by hypoxia in colon cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PR39, a peptide regulator of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relevance of cell proliferation, vascular endothelial growth factor, and basic fibroblast growth factor production to angiogenesis and tumorigenicity in human glioma cell lines

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding and regulation of HIF-1alpha by a subunit of the proteasome complex, PSMA7

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia in a human intracerebral glioma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF-1: mediator of physiological and pathophysiological responses to hypoxia

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Overexpression of hypoxia-inducible factor 1alpha in common human cancers and their metastases

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of in vitro meningioma proliferation after growth factor stimulation by calcium channel antagonists: Part II--Additional growth factors, growth factor receptor immunohistochemistry, and intracellular calcium measurements

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dimerization, DNA binding, and transactivation properties of hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: control of hypoxia-inducible factor-1 activity by nitric oxide

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential expression of MMAC/PTEN in glioblastoma multiforme: relationship to localization and prognosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIF-1 alpha is required for solid tumor formation and embryonic vascularization.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the vascular permeability factor/vascular endothelial growth factor gene in central nervous system neoplasms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Somatic mutations of the von Hippel-Lindau tumor suppressor gene and loss of heterozygosity on chromosome 3p in human glial tumors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1alpha is a positive factor in solid tumor growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential regulation of VEGF, HIF1alpha and angiopoietin-1, -2 and -4 by hypoxia and ionizing radiation in human glioblastoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia regulates gene expression of alveolar epithelial transport proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of hypoxia-inducible factor 1: mechanisms and consequences

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Delayed vascular changes after antiangiogenic therapy with antivascular endothelial growth factor antibodies in human glioma xenografts in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nonhypoxic pathway mediates the induction of hypoxia-inducible factor 1alpha in vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of hypoxia-inducible factor 1alpha in brain tumors: association with angiogenesis, invasion, and progression

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxia-inducible factor 1alpha/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The hypoxic response of tumors is dependent on their microenvironment.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor receptor transcriptionally up-regulates vascular endothelial growth factor expression in human glioblastoma cells via a pathway involving phosphatidylinositol 3'-kinase and distinct from that induced by hypoxia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparative measurements of hypoxia in human brain tumors using needle electrodes and EF5 binding

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of HIF-1alpha in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/16612574

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S11060-005-9103-Z

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

1 reference

Europe PubMed Central

13 February 2018

http://europepmc.org/abstract/MED/16612574

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