(Q48588727)

13 February 2018

title

CNTF reverses obesity-induced insulin resistance by activating skeletal muscle AMPK. (English)

1 reference

13 February 2018

0 references

1 reference

1 reference

4

1 reference

13 February 2018

Nicolas Dzamko

Nicolas Dzamko

2

0 references

Walter G Thomas

Walter G Thomas

3

0 references

Matthias Ernst

Matthias Ernst

5

0 references

Bruce Ernest Kemp

Bruce E Kemp

7

0 references

David Carling

David Carling

6

0 references

author name string

Matthew J Watt

1

1 reference

13 February 2018

Mark A Febbraio

8

1 reference

13 February 2018

Gregory R Steinberg

9

1 reference

13 February 2018

language of work or name

English

0 references

publication date

9 April 2006

1 reference

13 February 2018

published in

Nature Medicine

1 reference

13 February 2018

volume

12

1 reference

13 February 2018

issue

5

1 reference

13 February 2018

page(s)

541-548

1 reference

13 February 2018

https://scigraph.springernature.com/pub.10.1038/nm1383

exact match

0 references

cites work

Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

1 reference

7 January 2021

Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance

1 reference

7 January 2021

Ciliary neurotrophic factor improves diabetic parameters and hepatic steatosis and increases basal metabolic rate in db/db mice

1 reference

7 January 2021

Neurogenesis in the hypothalamus of adult mice: potential role in energy balance

1 reference

7 January 2021

Immunohistochemical localization of ciliary neurotrophic factor receptor alpha expression in the rat nervous system

1 reference

7 January 2021

Expression of ciliary neurotrophic factor receptor-alpha messenger RNA in neonatal and adult rat brain: an in situ hybridization study.

1 reference

7 January 2021

LIFR beta and gp130 as heterodimerizing signal transducers of the tripartite CNTF receptor

1 reference

7 January 2021

Unlike leptin, ciliary neurotrophic factor does not reverse the starvation-induced changes of serum corticosterone and hypothalamic neuropeptide levels but induces expression of hypothalamic inhibitors of leptin signaling.

1 reference

7 January 2021

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss

1 reference

7 January 2021

Skeletal muscle metabolism is a major determinant of resting energy expenditure

1 reference

7 January 2021

Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36.

1 reference

7 January 2021

Cellular mechanisms of insulin resistance

1 reference

7 January 2021

Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase

1 reference

7 January 2021

AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism

1 reference

7 January 2021

Weight-reducing effects of the plasma protein encoded by the obese gene

1 reference

7 January 2021

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

1 reference

7 January 2021

Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action

1 reference

7 January 2021

Endurance training partially reverses dietary-induced leptin resistance in rodent skeletal muscle

1 reference

7 January 2021

A family of cytokine-inducible inhibitors of signalling

1 reference

7 January 2021

Identification of SOCS-3 as a potential mediator of central leptin resistance

1 reference

7 January 2021

Enhanced leptin sensitivity and attenuation of diet-induced obesity in mice with haploinsufficiency of Socs3.

1 reference

7 January 2021

Socs3 deficiency in the brain elevates leptin sensitivity and confers resistance to diet-induced obesity

1 reference

7 January 2021

Defective gp130-mediated signal transducer and activator of transcription (STAT) signaling results in degenerative joint disease, gastrointestinal ulceration, and failure of uterine implantation

1 reference

7 January 2021

LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

1 reference

7 January 2021

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

1 reference

7 January 2021

Signaling of human ciliary neurotrophic factor (CNTF) revisited. The interleukin-6 receptor can serve as an alpha-receptor for CTNF

1 reference

7 January 2021

Inhibition of STAT3 prevents neointima formation by inhibiting proliferation and promoting apoptosis of neointimal smooth muscle cells

1 reference

7 January 2021

Ciliary neurotrophic factorAx15 alters energy homeostasis, decreases body weight, and improves metabolic control in diet-induced obese and UCP1-DTA mice

1 reference

7 January 2021

Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

1 reference

7 January 2021

Identification and expression cloning of a leptin receptor, OB-R

1 reference

7 January 2021

The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors

1 reference

7 January 2021

STAT3 signalling is required for leptin regulation of energy balance but not reproduction

1 reference

7 January 2021

1 reference

7 January 2021

The role of SOCS-3 in leptin signaling and leptin resistance

1 reference

7 January 2021

Chronic leptin administration decreases fatty acid uptake and fatty acid transporters in rat skeletal muscle

1 reference

7 January 2021

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

1 reference

7 January 2021

AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise

1 reference

7 January 2021

Leptin Directly Alters Lipid Partitioning in Skeletal Muscle

1 reference

7 January 2021

Insulin, but not contraction, activates Akt/PKB in isolated rat skeletal muscle.

1 reference

7 January 2021

Beta-adrenergic stimulation of skeletal muscle HSL can be overridden by AMPK signaling.

1 reference

7 January 2021

Isolation and characterization of human muscle cells

1 reference

7 January 2021

Acute IL-6 treatment increases fatty acid turnover in elderly humans in vivo and in tissue culture in vitro

1 reference

7 January 2021

Receptor recognition sites of cytokines are organized as exchangeable modules. Transfer of the leukemia inhibitory factor receptor-binding site from ciliary neurotrophic factor to interleukin-6.

1 reference

7 January 2021

AMPK signaling in contracting human skeletal muscle: acetyl-CoA carboxylase and NO synthase phosphorylation

1 reference

7 January 2021

Identifiers

DOI

10.1038/NM1383

1 reference

13 February 2018

Dimensions Publication ID

0 references

1 reference

13 February 2018