(Q48619357)

13 February 2018

title

Elevated levels of circulating CD4(+) CRTh2(+) T cells characterize severe asthma. (English)

1 reference

13 February 2018

author name string

N S Palikhe

1

1 reference

13 February 2018

C Laratta

2

1 reference

13 February 2018

D Nahirney

3

1 reference

13 February 2018

D Vethanayagam

4

1 reference

13 February 2018

M Bhutani

5

1 reference

13 February 2018

H Vliagoftis

6

1 reference

13 February 2018

L Cameron

7

1 reference

13 February 2018

publication date

15 April 2016

1 reference

13 February 2018

Clinical & Experimental Allergy

published in

1 reference

13 February 2018

volume

46

1 reference

13 February 2018

issue

6

1 reference

13 February 2018

page(s)

825-836

1 reference

13 February 2018

Asthma phenotypes: the evolution from clinical to molecular approaches

cites work

1 reference

T-helper type 2-driven inflammation defines major subphenotypes of asthma.

21 January 2018

1 reference

Mepolizumab for prednisone-dependent asthma with sputum eosinophilia

21 January 2018

1 reference

Oral glucocorticoid-sparing effect of mepolizumab in eosinophilic asthma.

21 January 2018

1 reference

Lebrikizumab in moderate-to-severe asthma: pooled data from two randomised placebo-controlled studies

21 January 2018

1 reference

Lebrikizumab treatment in adults with asthma

21 January 2018

1 reference

CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease

21 January 2018

1 reference

Cyclooxygenase-2/prostaglandin D2/CRTH2 pathway mediates double-stranded RNA-induced enhancement of allergic airway inflammation

21 January 2018

1 reference

Prostaglandin D2 causes preferential induction of proinflammatory Th2 cytokine production through an action on chemoattractant receptor-like molecule expressed on Th2 cells

21 January 2018

1 reference

Prostaglandin D2 activates group 2 innate lymphoid cells through chemoattractant receptor-homologous molecule expressed on TH2 cells

21 January 2018

1 reference

Pharmacologic profile of OC000459, a potent, selective, and orally active D prostanoid receptor 2 antagonist that inhibits mast cell-dependent activation of T helper 2 lymphocytes and eosinophils

21 January 2018

1 reference

A dominant role for chemoattractant receptor-homologous molecule expressed on T helper type 2 (Th2) cells (CRTH2) in mediating chemotaxis of CRTH2+ CD4+ Th2 lymphocytes in response to mast cell supernatants.

21 January 2018

1 reference

Novel function of CRTH2 in preventing apoptosis of human Th2 cells through activation of the phosphatidylinositol 3-kinase pathway.

21 January 2018

1 reference

Prostaglandin D2 plays an essential role in chronic allergic inflammation of the skin via CRTH2 receptor.

21 January 2018

1 reference

CRTH2 plays an essential role in the pathophysiology of Cry j 1-induced pollinosis in mice

21 January 2018

1 reference

CRTH2 antagonism significantly ameliorates airway hyperreactivity and downregulates inflammation-induced genes in a mouse model of airway inflammation.

21 January 2018

1 reference

Accumulation of CRTH2-positive leukocytes in human allergic nasal mucosa.

21 January 2018

1 reference

The single nucleotide polymorphism CRTh2 rs533116 is associated with allergic asthma and increased expression of CRTh2.

21 January 2018

1 reference

Differentiation stage determines pathologic and protective allergen-specific CD4+ T-cell outcomes during specific immunotherapy

21 January 2018

1 reference

Prostaglandin D₂ pathway upregulation: relation to asthma severity, control, and TH2 inflammation

21 January 2018

1 reference

Association of a new-type prostaglandin D2 receptor CRTH2 with circulating T helper 2 cells in patients with atopic dermatitis

21 January 2018

1 reference

Hematopoietic prostaglandin D synthase defines a proeosinophilic pathogenic effector human T(H)2 cell subpopulation with enhanced function

21 January 2018

1 reference

Maintenance and polarization of human TH2 central memory T cells by thymic stromal lymphopoietin-activated dendritic cells.

21 January 2018

1 reference

Migration, maintenance and recall of memory T cells in peripheral tissues

21 January 2018

1 reference

Naive and memory T cells show distinct pathways of lymphocyte recirculation

21 January 2018

1 reference

Long-lived Th2 memory in experimental allergic asthma

21 January 2018

1 reference

The clinical and genetic features of COPD-asthma overlap syndrome

21 January 2018

1 reference

Genome-wide association study to identify genetic determinants of severe asthma.

21 January 2018

1 reference

A novel mutation in CD83 results in the development of a unique population of CD4+ T cells

21 January 2018

1 reference

Increased numbers of activated group 2 innate lymphoid cells in the airways of patients with severe asthma and persistent airway eosinophilia.

21 January 2018

1 reference

Enhanced innate type 2 immune response in peripheral blood from patients with asthma

21 January 2018

1 reference

Persistence of asthma requires multiple feedback circuits involving type 2 innate lymphoid cells and IL-33.

21 January 2018

1 reference

The role of ILC2 in pathology of type 2 inflammatory diseases

21 January 2018

1 reference

Mechanisms of glucocorticoid action and insensitivity in airways disease.

21 January 2018

1 reference

Glucocorticosteroid inhibition of cytokine production: relevance to antiallergic actions

21 January 2018

1 reference

Critical role of mitochondria, but not caspases, during glucocorticosteroid-induced human eosinophil apoptosis

21 January 2018

1 reference

Acid sphingomyelinase is required for protection of effector memory T cells against glucocorticoid-induced cell death

21 January 2018

1 reference

Enhancement of MEK/ERK signaling promotes glucocorticoid resistance in CD4+ T cells

21 January 2018

1 reference

Rhinovirus-induced IL-25 in asthma exacerbation drives type 2 immunity and allergic pulmonary inflammation

21 January 2018

1 reference

Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis

21 January 2018

1 reference

Heightened response of eosinophilic asthmatic patients to the CRTH2 antagonist OC000459.

21 January 2018

1 reference

Prostaglandin D2 is a potent chemoattractant for human eosinophils that acts via a novel DP receptor

21 January 2018

1 reference

Distinctive Blood Eosinophilic Phenotypes and Cytokine Patterns in Eosinophilic Esophagitis, Inflammatory Bowel Disease and Airway Allergy

21 January 2018

1 reference

Apoptosis and B-Cell Lymphoma-2 of Peripheral Blood T Lymphocytes and Soluble Fas in Patients with Allergic Asthma

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1111/CEA.12741

1 reference

13 February 2018

1 reference

13 February 2018