(Q48658335)

English

Diversity-Based Organic Synthesis in the Era of Genomics and Proteomics NRC publication no. 43843. David Thomas is a senior colleague and mentor

scientific article published in January 2001

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scholarly article

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Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

Diversity-Based Organic Synthesis in the Era of Genomics and Proteomics NRC publication no. 43843. David Thomas is a senior colleague and mentor (English)

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

0 references

author name string

Prabhat Arya

1

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

Doug T. H. Chou

2

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

Myung-Gi Baek

3

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Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

publication date

1 January 2001

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Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

Angewandte Chemie

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Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

40

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Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

2

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

339-346

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

Target-oriented and diversity-oriented organic synthesis in drug discovery

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Chemical genetics resulting from a passion for synthetic organic chemistry.

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Disruption of transforming growth factor beta signaling by a mutation that prevents transphosphorylation within the receptor complex.

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Probing the role of homomeric and heteromeric receptor interactions in TGF-beta signaling using small molecule dimerizers

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Recent advances in olefin metathesis and its application in organic synthesis

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The development and therapeutic potential of protein kinase inhibitors

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Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors

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Synthesis of C2 alkynylated purines, a new family of potent inhibitors of cyclin-dependent kinases

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21 January 2018

Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine

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Structural basis for specificity and potency of a flavonoid inhibitor of human CDK2, a cell cycle kinase.

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Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors

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Myoseverin, a microtubule-binding molecule with novel cellular effects

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21 January 2018

Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]

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The Art and Science of Total Synthesis at the Dawn of the Twenty-First Century

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Facile Preparation of 2,6-Disubstituted Purines Using Solid-Phase Chemistry

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21 January 2018

Selenium-Based Solid-Phase Synthesis of Benzopyrans I: Applications to Combinatorial Synthesis of Natural Products

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Selenium-Based Solid-Phase Synthesis of Benzopyrans II: Applications to Combinatorial Synthesis of Medicinally Relevant Small Organic Molecules

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21 January 2018

Identifiers

10.1002/1521-3773(20010119)40:2<339::AID-ANIE339>3.0.CO;2-J

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/11180320

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