(Q48670149)

14 February 2018

title

Rai is a new regulator of neural progenitor migration and glioblastoma invasion. (English)

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14 February 2018

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Paola Brescia

5

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Paolo Gaetani

8

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14 February 2018

Serena Pellegatta

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Serena Pellegatta

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author name string

Daniela Osti

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Federica Pisati

4

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Lorenzo Fornasari

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Daniel Levi

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Piergiuseppe Colombo

9

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14 February 2018

Anna Ferri

10

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Silvia Nicolis

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Gaetano Finocchiaro

12

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Giuliana Pelicci

13

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publication date

1 May 2012

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14 February 2018

published in

Stem Cells

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14 February 2018

volume

30

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issue

5

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page(s)

817-832

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Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma

cites work

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Malignant astrocytic glioma: genetics, biology, and paths to treatment

21 January 2018

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Identification of human brain tumour initiating cells

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Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma

21 January 2018

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A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain

21 January 2018

1 reference

Evolution of Shc functions from nematode to human

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The neuron-specific Rai (ShcC) adaptor protein inhibits apoptosis by coupling Ret to the phosphatidylinositol 3-kinase/Akt signaling pathway.

21 January 2018

1 reference

The Rai (Shc C) adaptor protein regulates the neuronal stress response and protects against cerebral ischemia

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Shc signaling in differentiating neural progenitor cells.

21 January 2018

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Shc3 affects human high-grade astrocytomas survival

21 January 2018

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Comprehensive genomic characterization defines human glioblastoma genes and core pathways

21 January 2018

1 reference

Neural stem cell isolation and characterization

21 January 2018

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Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines

21 January 2018

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Olig2-regulated lineage-restricted pathway controls replication competence in neural stem cells and malignant glioma

21 January 2018

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Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1.

21 January 2018

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Direct evidence for homotypic, glia-independent neuronal migration.

21 January 2018

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Alterations of the Notch pathway in lung cancer.

21 January 2018

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An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation.

21 January 2018

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Doublecortin is preferentially expressed in invasive human brain tumors

21 January 2018

1 reference

Evaluation of sensitivity and specificity of doublecortin immunostatining for the detection of infiltrating glioma cells.

21 January 2018

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BMI1 sustains human glioblastoma multiforme stem cell renewal

21 January 2018

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ELDA: extreme limiting dilution analysis for comparing depleted and enriched populations in stem cell and other assays

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Stem cells, cancer, and cancer stem cells

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Network of tangential pathways for neuronal migration in adult mammalian brain

21 January 2018

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Neuronal migration in the adult brain: are we there yet?

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Matrix metalloproteinases: regulators of the tumor microenvironment

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ADAMs in cancer cell proliferation and progression.

21 January 2018

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Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis

21 January 2018

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Spatial and temporal specification of neural fates by transcription factor codes.

21 January 2018

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The Wnt/beta-catenin pathway directs neuronal differentiation of cortical neural precursor cells

21 January 2018

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Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3.

21 January 2018

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Neurogenin and NeuroD direct transcriptional targets and their regulatory enhancers

21 January 2018

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Selective use of ADAM10 and ADAM17 in activation of Notch1 signaling

21 January 2018

1 reference

Notch signaling mediates hypoxia-induced tumor cell migration and invasion

21 January 2018

1 reference

Hypoxia potentiates Notch signaling in breast cancer leading to decreased E-cadherin expression and increased cell migration and invasion

21 January 2018

1 reference

SNAI2/Slug promotes growth and invasion in human gliomas

21 January 2018

1 reference

Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1

21 January 2018

1 reference

Identification of tumor-initiating cells in a highly aggressive brain tumor using promoter activity of nucleostemin.

21 January 2018

1 reference

A subpopulation of CD26+ cancer stem cells with metastatic capacity in human colorectal cancer

21 January 2018

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Distinct populations of cancer stem cells determine tumor growth and metastatic activity in human pancreatic cancer

21 January 2018

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Cancer stem cells from human breast tumors are involved in spontaneous metastases in orthotopic mouse models

21 January 2018

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Enrichment of cancer stem cells based on heterogeneity of invasiveness

21 January 2018

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Elevated invasive potential of glioblastoma stem cells

21 January 2018

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RNAi reveals doublecortin is required for radial migration in rat neocortex

21 January 2018

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Doublecortin is necessary for the migration of adult subventricular zone cells from neurospheres.

21 January 2018

1 reference

Profiling of genes expressed by PTEN haploinsufficient neural precursor cells.

21 January 2018

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Gene expression profiling and genetic markers in glioblastoma survival.

21 January 2018

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Coupling of cell migration with neurogenesis by proneural bHLH factors

21 January 2018

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A short upstream promoter region mediates transcriptional regulation of the mouse doublecortin gene in differentiating neurons

21 January 2018

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Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation

21 January 2018

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Nonredundant functions for Akt isoforms in astrocyte growth and gliomagenesis in an orthotopic transplantation model.

21 January 2018

1 reference

Transfection with anti-p65 intrabody suppresses invasion and angiogenesis in glioma cells by blocking nuclear factor-kappaB transcriptional activity.

21 January 2018

1 reference

Aberrant constitutive activation of nuclear factor kappaB in glioblastoma multiforme drives invasive phenotype

21 January 2018

1 reference

Notch signalling regulates stem cell numbers in vitro and in vivo

21 January 2018

1 reference

The functional role of Notch signaling in human gliomas

21 January 2018

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Tenascin-C is a novel RBPJkappa-induced target gene for Notch signaling in gliomas

21 January 2018

1 reference

The oncogenic roles of Notch1 in astrocytic gliomas in vitro and in vivo

21 January 2018

1 reference

Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells

21 January 2018

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Brain tumor stem cells maintain overall phenotype and tumorigenicity after in vitro culturing in serum-free conditions

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/STEM.1056

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14 February 2018

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14 February 2018