(Q48670602)

14 February 2018

title

Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease (English)

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14 February 2018

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Paul Lingor

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Lars Tatenhorst

object named as

Lars Tatenhorst

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Jan C Koch

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Jan C Koch

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Kim Ann Saal

3

object named as

Kim-Ann Saal

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14 February 2018

author name string

Éva M Szegő

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Mathias Bähr

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publication date

1 August 2014

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14 February 2018

Journal of Neuropathology & Experimental Neurology

published in

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volume

73

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issue

8

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14 February 2018

page(s)

770-779

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14 February 2018

Axon degeneration in Parkinson's disease

cites work

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Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway

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Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP.

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ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.

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Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease

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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase

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Rho kinase, a promising drug target for neurological disorders

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Characterization of the striatal 6-OHDA model of Parkinson's disease in wild type and alpha-synuclein-deleted mice

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Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.

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Sprouting of dopamine terminals and altered dopamine release and uptake in Parkinsonian dyskinaesia.

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Axonal alpha-synuclein aggregates herald centripetal degeneration of cardiac sympathetic nerve in Parkinson's disease

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Behavioral characterization of a unilateral 6-OHDA-lesion model of Parkinson's disease in mice

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ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells

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The protective effect of fasudil on the structure and function of cardiac mitochondria from rats with type 2 diabetes induced by streptozotocin with a high-fat diet is mediated by the attenuation of oxidative stress

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Obstacles to the development of a neuroprotective therapy for Parkinson's disease

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Glial cell line-derived neurotrophic factor induces neuronal sprouting in human brain

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21 January 2018

Identifiers

DOI

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14 February 2018

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14 February 2018