(Q24609725)

5

0 references

Lars Tönges

object named as

Lars Tönges

1

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Paul Lingor

object named as

Paul Lingor

9

0 references

author name string

Tobias Frank

2

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Kim A Saal

4

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Éva M Szego

6

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Mathias Bähr

7

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Jochen H Weishaupt

describes a project that uses

8

0 references

language of work or name

English

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publication date

November 2012

0 references

published in

Brain

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volume

135

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issue

Pt 11

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page(s)

3355-70

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ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3501973/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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TCH346 as a neuroprotective drug in Parkinson's disease: a double-blind, randomised, controlled trial

7 April 2017

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TCH346 prevents motor symptoms and loss of striatal FDOPA uptake in bilaterally MPTP-treated primates

7 April 2017

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Specificity and mechanism of action of some commonly used protein kinase inhibitors

7 April 2017

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Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis

7 April 2017

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RTP801 is induced in Parkinson's disease and mediates neuron death by inhibiting Akt phosphorylation/activation

7 April 2017

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Parkinson's disease: mechanisms and models

7 April 2017

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7 April 2017

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Dose translation from animal to human studies revisited

7 April 2017

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Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.

7 April 2017

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ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.

27 September 2017

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AAV transduction of dopamine neurons with constitutively active Rheb protects from neurodegeneration and mediates axon regrowth.

27 September 2017

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Exogenous α-synuclein fibrils induce Lewy body pathology leading to synaptic dysfunction and neuron death

27 September 2017

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Age and α-synuclein expression interact to reveal a dependence of dopaminergic axons on endogenous Akt/PKB signaling.

27 September 2017

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JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.

27 September 2017

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Neurotoxic in vivo models of Parkinson's disease recent advances.

27 September 2017

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The role of Rho protein signaling in hypertension.

27 September 2017

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Intracellular signalling pathways in dopamine cell death and axonal degeneration.

27 September 2017

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Clinical progression in Parkinson disease and the neurobiology of axons.

27 September 2017

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Leucine-rich repeat kinase 2 mutations and Parkinson's disease: three questions

27 September 2017

1 reference

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Why have we failed to achieve neuroprotection in Parkinson's disease?

27 September 2017

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Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson's disease.

27 September 2017

1 reference

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ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells

27 September 2017

1 reference

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Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo

27 September 2017

1 reference

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Oncoprotein Akt/PKB induces trophic effects in murine models of Parkinson's disease

27 September 2017

1 reference

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Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease

27 September 2017

1 reference

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Axon degeneration mechanisms: commonality amid diversity

27 September 2017

1 reference

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Rho kinase, a promising drug target for neurological disorders

27 September 2017

1 reference

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Parkinson's prevalence estimated by a state registry

27 September 2017

1 reference

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Targeting programmed cell death in neurodegenerative diseases

27 September 2017

1 reference

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NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease

27 September 2017

1 reference

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Axon pathology in neurological disease: a neglected therapeutic target

27 September 2017

1 reference

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Axonal self-destruction and neurodegeneration

27 September 2017

1 reference

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The parkinsonian toxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP): a technical review of its utility and safety

27 September 2017

1 reference

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Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity

27 September 2017

1 reference

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Brain-derived neurotrophic factor augments rotational behavior and nigrostriatal dopamine turnover in vivo

27 September 2017

1 reference

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Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Neuroprotection by bromocriptine against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Partial protection from the dopaminergic neurotoxin N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine by four different antioxidants in the mouse

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Long-term treatment with a Rho-kinase inhibitor improves monocrotaline-induced fatal pulmonary hypertension in rats

30 May 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Coenzyme Q10 attenuates the 1-methyl-4-phenyl-1,2,3,tetrahydropyridine (MPTP) induced loss of striatal dopamine and dopaminergic axons in aged mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Suppression of Rho-kinase activity promotes axonal growth on inhibitory CNS substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Distribution of Rho-kinase in the bovine brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Presynaptic alpha-synuclein aggregates, not Lewy bodies, cause neurodegeneration in dementia with Lewy bodies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Axonal degeneration of nigra-striatum dopaminergic neurons induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Midbrain dopaminergic neurons are protected from radical induced damage by GDF-5 application. Short communication

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

A30P α-synuclein impairs dopaminergic fiber regeneration and interacts with L-DOPA replacement in MPTP-treated mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Efficacy of Rho-kinase inhibition in promoting cell survival and reducing reactive gliosis in the rodent retina

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Direct Rho-associated kinase inhibition [correction of inhibiton] induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Effect of fasudil hydrochloride, a protein kinase inhibitor, on cerebral vasospasm and delayed cerebral ischemic symptoms after aneurysmal subarachnoid hemorrhage

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FBRAIN%2FAWS254

Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

CEP-1347/KT-7515, an inhibitor of c-jun N-terminal kinase activation, attenuates the 1-methyl-4-phenyl tetrahydropyridine-mediated loss of nigrostriatal dopaminergic neurons In vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3501973

Postnatal changes in Rho and Rho-related proteins in the mouse brain

28 November 2018

1 reference

12 December 2020

Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity

1 reference

12 December 2020

Pramipexole inhibits lipid peroxidation and reduces injury in the substantia nigra induced by the dopaminergic neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57BL/6 mice

1 reference

12 December 2020

Myosin II activity is required for severing-induced axon retraction in vitro

1 reference

12 December 2020

CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury

1 reference

12 December 2020

Neuroprotection in Parkinson's disease: and now for something completely different?

1 reference

12 December 2020

Selective retention of MPP+ within the monoaminergic systems of the primate brain following MPTP administration: an in vivo autoradiographic study

1 reference

12 December 2020

Inactivation of Rho signaling pathway promotes CNS axon regeneration

1 reference

12 December 2020

Loss of striatal dopaminergic terminals during the early stage in response to MPTP injection in C57BL/6 mice

1 reference

12 December 2020

Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study

1 reference

12 December 2020

Identifiers

DOI

10.1093/BRAIN/AWS254

1 reference

1 reference

1 reference

PubMed publication ID

23087045

1 reference