(Q48677705)

14 February 2018

title

Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions (English)

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14 February 2018

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Min-Koo Choi

1

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14 February 2018

Qing-Ri Jin

2

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14 February 2018

Yeong-Lim Choi

3

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14 February 2018

Sung-Hoon Ahn

4

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14 February 2018

Myung-Ae Bae

5

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14 February 2018

Im-Sook Song

6

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14 February 2018

publication date

24 February 2011

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Biopharmaceutics and Drug Disposition

published in

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14 February 2018

volume

32

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issue

3

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14 February 2018

page(s)

175-184

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14 February 2018

Quantitative evaluation of pharmacokinetic inhibition of CYP3A substrates by ketoconazole: a simulation study

cites work

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Transporter-mediated drug interactions: clinical implications and in vitro assessment

21 January 2018

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Effect of ketoconazole on ritonavir and saquinavir concentrations in plasma and cerebrospinal fluid from patients infected with human immunodeficiency virus.

21 January 2018

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The need for multiple doses of 400 mg ketoconazole as a precipitant inhibitor of a CYP3A substrate in an in vivo drug-drug interaction study.

21 January 2018

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Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes

21 January 2018

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Rifampin markedly decreases and gemfibrozil increases the plasma concentrations of atorvastatin and its metabolites

21 January 2018

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Pharmacokinetic interactions with rifampicin : clinical relevance

21 January 2018

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effect of OATP1B transporter inhibition on the pharmacokinetics of atorvastatin in healthy volunteers

21 January 2018

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Bosentan is a substrate of human OATP1B1 and OATP1B3: inhibition of hepatic uptake as the common mechanism of its interactions with cyclosporin A, rifampicin, and sildenafil

21 January 2018

1 reference

Identification of multispecific organic anion transporter 2 expressed predominantly in the liver

21 January 2018

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The effect of SLCO1B1*15 on the disposition of pravastatin and pitavastatin is substrate dependent: the contribution of transporting activity changes by SLCO1B1*15.

21 January 2018

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Establishment and characterization of Mardin-Darby canine kidney cells stably expressing human organic anion transporters

21 January 2018

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Quantitative determination of olmesartan in human plasma and urine by liquid chromatography coupled to tandem mass spectrometry.

21 January 2018

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Human organic anion transporting polypeptide-C (SLC21A6) is a major determinant of rifampin-mediated pregnane X receptor activation

21 January 2018

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Interactions of rifamycin SV and rifampicin with organic anion uptake systems of human liver

21 January 2018

1 reference

Can the pharmacokinetic characteristics of olmesartan medoxomil contribute to the improvement of blood pressure control?

21 January 2018

1 reference

Olmesartan medoxomil: recent clinical and experimental acquisitions

21 January 2018

1 reference

Pharmacokinetics of CS-866, a new angiotensin II receptor blocker, in healthy subjects

21 January 2018

1 reference

Culture period-dependent change of function and expression of ATP-binding cassette transporters in Caco-2 cells

21 January 2018

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Multiple human isoforms of drug transporters contribute to the hepatic and renal transport of olmesartan, a selective antagonist of the angiotensin II AT1-receptor

21 January 2018

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Pharmacokinetic interaction between pravastatin and olmesartan in relation to SLCO1B1 polymorphism

21 January 2018

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Drug-drug interaction between pitavastatin and various drugs via OATP1B1.

21 January 2018

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Rifampicin alters atorvastatin plasma concentration on the basis of SLCO1B1 521T>C polymorphism

21 January 2018

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Pharmacokinetics and dose proportionality of ketoconazole in normal volunteers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/BDD.749

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14 February 2018

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14 February 2018