(Q48680527)

English

Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3.

scientific article published on 14 June 2016

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scholarly article

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Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of α-synuclein via SIRT1-deacetylated LC3. (English)

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Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

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http://europepmc.org/abstract/MED/27296520

8

object named as

Eng-King Tan

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14 February 2018

author name string

Yan-Jie Guo

1

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Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

Su-Yan Dong

2

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Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

Xin-Xin Cui

3

1 reference

Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

Ya Feng

4

1 reference

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14 February 2018

http://europepmc.org/abstract/MED/27296520

Te Liu

5

1 reference

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14 February 2018

http://europepmc.org/abstract/MED/27296520

Ming Yin

6

1 reference

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http://europepmc.org/abstract/MED/27296520

Wen-Juan Zhao

9

1 reference

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14 February 2018

http://europepmc.org/abstract/MED/27296520

Yun-Cheng Wu

10

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http://europepmc.org/abstract/MED/27296520

publication date

14 June 2016

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14 February 2018

http://europepmc.org/abstract/MED/27296520

Molecular Nutrition and Food Research

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http://europepmc.org/abstract/MED/27296520

60

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Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

10

1 reference

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14 February 2018

http://europepmc.org/abstract/MED/27296520

2161-2175

1 reference

Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

Therapeutic approaches in Parkinson's disease and related disorders

1 reference

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Beneficial action of resveratrol: How and why?

1 reference

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Deacetylation of nuclear LC3 drives autophagy initiation under starvation

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1 reference

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Effect of resveratrol on mitochondrial function: implications in parkin-associated familiar Parkinson's disease

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Resveratrol partially prevents rotenone-induced neurotoxicity in dopaminergic SH-SY5Y cells through induction of heme oxygenase-1 dependent autophagy

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Sulfate metabolites provide an intracellular pool for resveratrol generation and induce autophagy with senescence

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Neuroprotective effects of resveratrol in an MPTP mouse model of Parkinson's-like disease: possible role of SOCS-1 in reducing pro-inflammatory responses.

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Neuroprotective properties and mechanisms of resveratrol in in vitro and in vivo experimental cerebral stroke models

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Lysosomal impairment in Parkinson's disease

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The many faces of α-synuclein: from structure and toxicity to therapeutic target

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100 years of Lewy pathology.

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Autophagy induced by the class III histone deacetylase Sirt1 prevents prion peptide neurotoxicity

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Analytical method development for synthesized conjugated metabolites of trans-resveratrol, and application to pharmacokinetic studies

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Transgenic expression and activation of PGC-1α protect dopaminergic neurons in the MPTP mouse model of Parkinson's disease

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Resveratrol-activated AMPK/SIRT1/autophagy in cellular models of Parkinson's disease

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Effects of D-cycloserine on MPTP-induced behavioral and neurological changes: potential for treatment of Parkinson's disease dementia.

1 reference

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Preclinical biomarkers of Parkinson disease

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Pleiotropic mechanisms facilitated by resveratrol and its metabolites.

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trans-Resveratrol as a neuroprotectant.

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Resveratrol as a therapeutic agent for neurodegenerative diseases

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SIRT1 negatively regulates the mammalian target of rapamycin

1 reference

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1 reference

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AMP-activated protein kinase signaling activation by resveratrol modulates amyloid-beta peptide metabolism.

1 reference

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The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.

1 reference

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1 reference

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1 reference

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Neuroprotective effects of resveratrol on MPTP-induced neuron loss mediated by free radical scavenging

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Resveratrol, a red wine polyphenol, protects dopaminergic neurons in MPTP-treated mice

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Effect of resveratrol on antioxidant enzyme activities in the brain of healthy rat.

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Protocol for the MPTP mouse model of Parkinson's disease

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Substrate-specific activation of sirtuins by resveratrol

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High absorption but very low bioavailability of oral resveratrol in humans

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1 reference

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12 December 2020

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Identifiers

10.1002/MNFR.201600111

1 reference

Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

0 references

1 reference

Europe PubMed Central

14 February 2018

http://europepmc.org/abstract/MED/27296520

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