(Q48691605)

English

Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology.

scientific article published in January 2012

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/22279212

Transgenic expression of intraneuronal Aβ42 but not Aβ40 leads to cellular Aβ lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

0 references

Alzheimer's disease

1 reference

based on heuristic

inferred from title

Dietmar R. Thal

11

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Estibaliz Capetillo-Zarate

7

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

author name string

Dorothee Abramowski

1

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Sabine Rabe

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Ajeet Rijal Upadhaya

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Julia Reichwald

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Simone Danner

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Dieter Staab

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Haruyasu Yamaguchi

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Takaomi C Saido

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Karl-Heinz Wiederhold

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

Matthias Staufenbiel

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

language of work or name

0 references

publication date

1 January 2012

1 reference

Europe PubMed Central

PubMed publication ID

14 February 2018

http://europepmc.org/abstract/MED/22279212

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

32

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

1273-1283

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

On the structure of the human archicortex. I. The cornu ammonis. A Golgi and pigmentarchitectonic study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Secretion of Alzheimer beta/A4 protein (1-40) and intracellular retention of beta/A4 protein (1-42) in transfected COS cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endogenous serine protease inhibitor modulates epileptic activity and hippocampal long-term potentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta42 is essential for parenchymal and vascular amyloid deposition in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease: strategies for disease modification

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal overexpression of mutant amyloid precursor protein results in prominent deposition of cerebrovascular amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of myelin loss in frontal lobe white matter in vascular dementia, Alzheimer's disease, and dementia with Lewy bodies

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of complement system components during aging and amyloid deposition in APP transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of APP processing and trafficking pathways in the formation of amyloid beta-protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective vulnerability of different types of commissural neurons for amyloid beta-protein-induced neurodegeneration in APP23 mice correlates with dendritic tree morphology.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal beta-amyloid accumulation and synapse pathology in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Occurrence and co-localization of amyloid beta-protein and apolipoprotein E in perivascular drainage channels of wild-type and APP-transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Demonstration of Amyloid Deposits and Neurofibrillary Changes in Whole Brain Sections

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Is Alzheimer's disease a result of presynaptic failure? Synaptic dysfunctions induced by oligomeric beta-amyloid

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta-induced neuronal dysfunction in Alzheimer's disease: from synapses toward neural networks

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abeta40 inhibits amyloid deposition in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic separation and immunoblotting of aβ(1-40) and aβ (1-42).

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recommendations for straightforward and rigorous methods of counting neurons based on a computer simulation approach.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dynamics of Abeta turnover and deposition in different beta-amyloid precursor protein transgenic mouse models following gamma-secretase inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Electrophoretic Separation of βA4 Peptides (1–40) and (1–42)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffuse plaques associated with astroglial amyloid beta protein, possibly showing a disappearing stage of senile plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pyroglutamate formation influences solubility and amyloidogenicity of amyloid peptides

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dominant and differential deposition of distinct beta-amyloid peptide species, A beta N3(pE), in senile plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuron loss in APP transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotoxicity of Alzheimer's disease Aβ peptides is induced by small changes in the Aβ42 to Aβ40 ratio

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Fleecy amyloid deposits in the internal layers of the human entorhinal cortex are comprised of N-terminal truncated fragments of Abeta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid beta40/42 clearance across the blood-brain barrier following intra-ventricular injections in wild-type, apoE knock-out and human apoE3 or E4 expressing transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two amyloid precursor protein transgenic mouse models with Alzheimer disease-like pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal pyroglutamate-Abeta 3-42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

1 reference

https://pubmed.ncbi.nlm.nih.gov/22279212

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4586-11.2012

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

release_ciyhlehexjbjxcq4jld7xvqomm

1 reference

https://api.fatcat.wiki/v0/release/ciyhlehexjbjxcq4jld7xvqomm

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6796269&resulttype=core&format=json

12 May 2020

ResearchGate publication ID

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