(Q51059487)

English

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo.

scientific article published in April 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

A mouse model of amyloid beta oligomers: their contribution to synaptic alteration, abnormal tau phosphorylation, glial activation, and neuronal loss in vivo (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

phosphorylation

1 reference

based on heuristic

inferred from title

12

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30 January 2020

William L. Klein

15

object named as

William L Klein

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30 January 2020

author name string

Takami Tomiyama

1

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30 January 2020

Shogo Matsuyama

2

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30 January 2020

Hiroyuki Iso

3

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30 January 2020

Tomohiro Umeda

4

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30 January 2020

Hiroshi Takuma

5

1 reference

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30 January 2020

Kiyouhisa Ohnishi

6

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30 January 2020

Kenichi Ishibashi

7

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30 January 2020

Rie Teraoka

8

1 reference

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30 January 2020

Naomi Sakama

9

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

Takenari Yamashita

10

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30 January 2020

Kazuchika Nishitsuji

11

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30 January 2020

Hiroyuki Shimada

13

1 reference

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30 January 2020

Mary P Lambert

14

1 reference

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30 January 2020

Hiroshi Mori

16

1 reference

Europe PubMed Central

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30 January 2020

language of work or name

0 references

publication date

1 April 2010

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30 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

30

1 reference

Europe PubMed Central

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30 January 2020

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

4845-4856

1 reference

Europe PubMed Central

PMC publication ID

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30 January 2020

describes a project that uses

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6632783/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Deposition of beta-amyloid subtypes 40 and 42 differentiates dementia with Lewy bodies from Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta42 accumulation in human brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease is a synaptic failure

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta42 accumulation in Down syndrome brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

APP processing and synaptic function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NeuN, a neuronal specific nuclear protein in vertebrates

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oligomerization of Alzheimer's beta-amyloid within processes and synapses of cultured neurons and brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Syntaxin 5 interacts with presenilin holoproteins, but not with their N- or C-terminal fragments, and affects beta-amyloid peptide production

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intra- and extracellular Abeta and PHF in clinically evaluated cases of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurodegeneration and plasticity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Massive CA1/2 neuronal loss with intraneuronal and N-terminal truncated Abeta42 accumulation in a novel Alzheimer transgenic model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural oligomers of the amyloid-beta protein specifically disrupt cognitive function

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal Abeta causes the onset of early Alzheimer's disease-related cognitive deficits in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A dynamic relationship between intracellular and extracellular pools of Abeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A specific amyloid-beta protein assembly in the brain impairs memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of synaptophysin near cortical neurons containing oligomer Abeta in Alzheimer's disease brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular Abeta and cognitive deficits precede beta-amyloid deposition in transgenic arcAbeta mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intraneuronal beta-amyloid aggregates, neurodegeneration, and neuron loss in transgenic mice with five familial Alzheimer's disease mutations: potential factors in amyloid plaque formation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal antibodies that target pathological assemblies of Abeta

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Oligomer-Induced Aberrations in Synapse Composition, Shape, and Density Provide a Molecular Basis for Loss of Connectivity in Alzheimer's Disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Environmental change during postnatal development alters behaviour, cognitions and neurogenesis of mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by A beta oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Accelerating amyloid-beta fibrillization reduces oligomer levels and functional deficits in Alzheimer disease mouse models.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inverse correlation between amyloid precursor protein and synaptic plasticity in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Congo red and thioflavin-T analogs detect Abeta oligomers

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer disease models and human neuropathology: similarities and differences

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new amyloid beta variant favoring oligomerization in Alzheimer's-type dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta E22Delta variant induces synaptic alteration in mouse hippocampal slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationships between hippocampal atrophy, white matter disruption, and gray matter hypometabolism in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The E693Delta mutation in amyloid precursor protein increases intracellular accumulation of amyloid beta oligomers and causes endoplasmic reticulum stress-induced apoptosis in cultured cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel gene iba1 in the major histocompatibility complex class III region encoding an EF hand protein expressed in a monocytic lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A vector for expressing foreign genes in the brains and hearts of transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Diffusible, nonfibrillar ligands derived from Abeta1-42 are potent central nervous system neurotoxins

1 reference

https://pubmed.ncbi.nlm.nih.gov/20371804

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.5825-09.2010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

release_blc6liqghvgtjgfqzrnoxw7toa

1 reference

https://api.fatcat.wiki/v0/release/blc6liqghvgtjgfqzrnoxw7toa

24 November 2022

based on heuristic

mapped directly with Wikidata item

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20371804%20AND%20SRC:MED&resulttype=core&format=json

30 January 2020

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