(Q48828099)

English

Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease.

scientific article published in June 2005

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scholarly article

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Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Treatment with an amyloid-beta antibody ameliorates plaque load, learning deficits, and hippocampal long-term potentiation in a mouse model of Alzheimer's disease (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

based on heuristic

inferred from title

long-term potentiation

1 reference

based on heuristic

inferred from title

David M. Holtzman

6

object named as

David M Holtzman

2 references

Europe PubMed Central

15 February 2018

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

Yukitoshi Izumi

2

object named as

Yukitoshi Izumi

1 reference

Europe PubMed Central

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13 January 2020

author name string

Richard E Hartman

1

1 reference

Europe PubMed Central

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13 January 2020

Kelly R Bales

3

1 reference

Europe PubMed Central

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13 January 2020

Steven M Paul

4

1 reference

Europe PubMed Central

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13 January 2020

David F Wozniak

5

1 reference

Europe PubMed Central

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13 January 2020

language of work or name

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publication date

1 June 2005

1 reference

Europe PubMed Central

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13 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

25

1 reference

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13 January 2020

26

1 reference

Europe PubMed Central

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13 January 2020

6213-6220

1 reference

Europe PubMed Central

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13 January 2020

Early phenotypic changes in transgenic mice that overexpress different mutants of amyloid precursor protein in brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Adaptation of the circular platform spatial memory task for mice: use in detecting cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral disturbances in transgenic mice overexpressing the V717F beta-amyloid precursor protein.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral disturbances without amyloid deposits in mice overexpressing human amyloid precursor protein with Flemish (A692G) or Dutch (E693Q) mutation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroanatomical abnormalities in behaviorally characterized APP(V717F) transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo synaptic transmission in young and aged amyloid precursor protein transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A learning deficit related to age and beta-amyloid plaques in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of cognitive impairment or decline in preclinical Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence that age-associated memory impairment is not a normal variant of aging.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A transcriptionally [correction of transcriptively] active complex of APP with Fe65 and histone acetyltransferase Tip60

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral phenotyping of GFAP-apoE3 and -apoE4 transgenic mice: apoE4 mice show profound working memory impairments in the absence of Alzheimer's-like neuropathology

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reduced corpus callosum, fornix and hippocampus in PDAPP transgenic mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Episodic-like memory in animals: psychological criteria, neural mechanisms and the value of episodic-like tasks to investigate animal models of neurodegenerative disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathologic correlates of nondemented aging, mild cognitive impairment, and early-stage Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-independent and age-related deficits in visuospatial learning, sleep-wake states, thermoregulation and motor activity in PDAPP mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The relationship between Abeta and memory in the Tg2576 mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plaque-associated disruption of CSF and plasma amyloid-beta (Abeta) equilibrium in a mouse model of Alzheimer's disease.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Non-Fc-mediated mechanisms are involved in clearance of amyloid-beta in vivo by immunotherapy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid-beta immunization in Alzheimer's disease transgenic mouse models and wildtype mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apolipoprotein E markedly facilitates age-dependent cerebral amyloid angiopathy and spontaneous hemorrhage in amyloid precursor protein transgenic mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parallels between Down syndrome dementia and Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dissection of amyloid-beta precursor protein-dependent transcriptional transactivation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Search strategies used by APP transgenic mice during navigation in the Morris water maze

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Passive amyloid immunotherapy clears amyloid and transiently activates microglia in a transgenic mouse model of amyloid deposition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kunitz protease inhibitor-containing amyloid beta protein precursor immunoreactivity in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurobiology of Down's syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Age-related CNS disorder and early death in transgenic FVB/N mice overexpressing Alzheimer amyloid precursor proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neurotrophic and neuroprotective effects of hAPP in transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term potentiation in awake mutant mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15987951

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.0664-05.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

release_l5fcdm6klbgnbdvrz3wb7bk2au

1 reference

https://api.fatcat.wiki/v0/release/l5fcdm6klbgnbdvrz3wb7bk2au

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15987951%20AND%20SRC:MED&resulttype=core&format=json

13 January 2020

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