(Q48871501)

16 February 2018

title

Microtubule-stabilising drugs for therapy of Alzheimer's disease and other neurodegenerative disorders with axonal transport impairments. (English)

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16 February 2018

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3

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John Q. Trojanowski

series ordinal

1

object named as

John Q Trojanowski

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16 February 2018

author name string

Amos B Smith

series ordinal

2

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16 February 2018

Virginia M-Y Lee

series ordinal

4

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16 February 2018

language of work or name

English

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publication date

1 May 2005

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16 February 2018

Expert Opinion on Pharmacotherapy

published in

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16 February 2018

volume

6

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16 February 2018

page(s)

683-686

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16 February 2018

issue

5

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16 February 2018

Neurodegenerative diseases: a decade of discoveries paves the way for therapeutic breakthroughs

cites work

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Peloruside A does not bind to the taxoid site on beta-tubulin and retains its activity in multidrug-resistant cell lines

21 January 2018

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Laulimalide and paclitaxel: a comparison of their effects on tubulin assembly and their synergistic action when present simultaneously

21 January 2018

1 reference

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Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction

21 January 2018

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The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.

21 January 2018

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Novel molecules that interact with microtubules and have functional activity similar to Taxol

21 January 2018

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Tau and axonopathy in neurodegenerative disorders

21 January 2018

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Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin

21 January 2018

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The clinical development of new mitotic inhibitors that stabilize the microtubule

21 January 2018

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{beta}-Amyloid-induced neurodegeneration and protection by structurally diverse microtubule-stabilizing agents.

21 January 2018

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Microtubule-stabilizing agents based on designed laulimalide analogues

21 January 2018

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A common pharmacophore for cytotoxic natural products that stabilize microtubules

21 January 2018

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Chemical modification of paclitaxel (Taxol) reduces P-glycoprotein interactions and increases permeation across the blood-brain barrier in vitro and in situ

21 January 2018

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Axonal transport defects: a common theme in neurodegenerative diseases

21 January 2018

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Design, synthesis, and evaluation of carbamate-substituted analogues of (+)-discodermolide.

21 January 2018

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The epothilones, eleutherobins, and related types of molecules

21 January 2018

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21 January 2018

Identifiers

DOI

10.1517/14656566.6.5.683

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16 February 2018

PubMed ID

15934894

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16 February 2018