(Q43305329)

10 February 2018

title

Tubulin polymerizing activity of dictyostatin-1, a polyketide of marine sponge origin (English)

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10 February 2018

3

Shirley A Pomponi

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10 February 2018

author name string

Richard A Isbrucker

1

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10 February 2018

Jennifer Cummins

2

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10 February 2018

Ross E Longley

4

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10 February 2018

Amy E Wright

5

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10 February 2018

language of work or name

English

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publication date

1 July 2003

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10 February 2018

published in

Biochemical Pharmacology

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10 February 2018

volume

66

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10 February 2018

issue

1

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10 February 2018

page(s)

75-82

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10 February 2018

Mechanism of action of antitumor drugs that interact with microtubules and tubulin

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Taxol in the management of cancers of the breast and the ovary

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Taxanes in lung cancer: a review with focus on the European experience

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

The microtubule-stabilizing agent discodermolide competitively inhibits the binding of paclitaxel (Taxol) to tubulin polymers, enhances tubulin nucleation reactions more potently than paclitaxel, and inhibits the growth of paclitaxel-resistant cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

A Common Pharmacophore for Taxol and the Epothilones Based on the Biological Activity of a Taxane Molecule Lacking a C-13 Side Chain†

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Isolation and structure of the cancer cell growth inhibitor dictyostatin 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Discodermolide/Dictyostatin hybrids: synthesis and biological evaluation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Isolation of bovine brain microtubule protein without glycerol: Polymerization kinetics change during purification cycles

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

A multidrug-resistant MCF-7 human breast cancer cell line which exhibits cross-resistance to antiestrogens and hormone-independent tumor growth in vivo.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

The potent microtubule-stabilizing agent (+)-discodermolide induces apoptosis in human breast carcinoma cells--preliminary comparisons to paclitaxel.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Structure-activity relationship studies of discodermolide and its semisynthetic acetylated analogs on microtubule function and cytotoxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Paclitaxel-induced cell death: where the cell cycle and apoptosis come together

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

The mode of action of taxol: apoptosis at low concentration and necrosis at high concentration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Differential in vitro association of vinca alkaloid-induced tubulin spiral filaments into aggregated spirals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

Interactions of the sponge-derived antimitotic tripeptide hemiasterlin with tubulin: comparison with dolastatin 10 and cryptophycin 1

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

(+)-Discodermolide binds to microtubules in stoichiometric ratio to tubulin dimers, blocks taxol binding and results in mitotic arrest

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0006-2952%2803%2900192-8

10.1016/S0006-2952(03)00192-8

7 January 2021

Identifiers

DOI

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10 February 2018

PubMed ID

12818367

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10 February 2018