(Q48909820)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Behavioral alterations associated with targeted disruption of exons 2 and 3 of the Disc1 gene in the mouse (English)

1 reference

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12 February 2020

1

1 reference

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12 February 2020

Taku Nagai

12

1 reference

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12 February 2020

Daisuke Mori

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Atsushi Enomoto

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Shinnosuke Yamada

2

1 reference

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12 February 2020

Motoki Tanaka

3

1 reference

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12 February 2020

Michiro Iizuka

4

1 reference

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12 February 2020

Hisashi Yano

5

1 reference

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12 February 2020

Daisuke Tsuboi

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Tomoki Nishioka

8

1 reference

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12 February 2020

Takashi Namba

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Yukihiko Iizuka

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Shimpei Kubota

11

1 reference

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12 February 2020

Daisuke Ibi

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Rui Wang

14

1 reference

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12 February 2020

Mayu Isotani-Sakakibara

16

1 reference

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12 February 2020

Naoya Asai

17

1 reference

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12 February 2020

Kazushi Kimura

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Hiroshi Kiyonari

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Takaya Abe

20

1 reference

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12 February 2020

Akira Mizoguchi

21

1 reference

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12 February 2020

Masahiro Sokabe

22

1 reference

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12 February 2020

Masahide Takahashi

23

1 reference

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12 February 2020

Kiyofumi Yamada

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Kozo Kaibuchi

25

1 reference

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12 February 2020

publication date

8 September 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

published in

Human Molecular Genetics

1 reference

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12 February 2020

volume

20

1 reference

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12 February 2020

issue

23

1 reference

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12 February 2020

page(s)

4666-4683

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21903668%20AND%20SRC:MED&resulttype=core&format=json

Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

12 February 2020

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

21 January 2018

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Association within a family of a balanced autosomal translocation with major mental illness

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Schizophrenia and affective disorders--cosegregation with a translocation at chromosome 1q42 that directly disrupts brain-expressed genes: clinical and P300 findings in a family.

21 January 2018

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Disrupted in schizophrenia 1 (DISC1): association with schizophrenia, schizoaffective disorder, and bipolar disorder

21 January 2018

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Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia

21 January 2018

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Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

21 January 2018

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Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

21 January 2018

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

21 January 2018

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Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling

21 January 2018

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

21 January 2018

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Disrupted-In-Schizophrenia 1, a candidate gene for schizophrenia, participates in neurite outgrowth

21 January 2018

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Disrupted-in-Schizophrenia-1 (DISC-1): mutant truncation prevents binding to NudE-like (NUDEL) and inhibits neurite outgrowth

21 January 2018

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DISC1 regulates neurotrophin-induced axon elongation via interaction with Grb2

21 January 2018

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

21 January 2018

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DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212

21 January 2018

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Dixdc1 is a critical regulator of DISC1 and embryonic cortical development

21 January 2018

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Understanding the role of DISC1 in psychiatric disease and during normal development

21 January 2018

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The DISC locus in psychiatric illness

21 January 2018

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Behavioral phenotypes of Disc1 missense mutations in mice

21 January 2018

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Dominant-negative DISC1 transgenic mice display schizophrenia-associated phenotypes detected by measures translatable to humans

21 January 2018

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Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice

21 January 2018

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Inducible expression of mutant human DISC1 in mice is associated with brain and behavioral abnormalities reminiscent of schizophrenia.

21 January 2018

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Schizophrenia-related neural and behavioral phenotypes in transgenic mice expressing truncated Disc1.

21 January 2018

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Disc1 is mutated in the 129S6/SvEv strain and modulates working memory in mice

21 January 2018

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A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

21 January 2018

1 reference

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Evolutionary constraints on the Disrupted in Schizophrenia locus

21 January 2018

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Primate disrupted-in-schizophrenia-1 (DISC1): high divergence of a gene for major mental illnesses in recent evolutionary history.

21 January 2018

1 reference

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DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms

21 January 2018

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Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited.

21 January 2018

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From maps to mechanisms through neuroimaging of schizophrenia

21 January 2018

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Deletion polymorphism of Disc1 is common to all 129 mouse substrains: implications for gene-targeting studies of brain function

21 January 2018

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Expression of Disrupted-In-Schizophrenia-1, a schizophrenia-associated gene, is prominent in the mouse hippocampus throughout brain development.

21 January 2018

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DISC1 (Disrupted in Schizophrenia-1) is expressed in limbic regions of the primate brain

21 January 2018

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Expression of fasciculation and elongation protein zeta-1 (FEZ1) in the developing rat brain

21 January 2018

1 reference

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Cloning and characterization of Disc1, the mouse ortholog of DISC1 (Disrupted-in-Schizophrenia 1).

21 January 2018

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A schizophrenia-associated mutation of DISC1 perturbs cerebral cortex development

21 January 2018

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Impact of the DISC1 Ser704Cys polymorphism on risk for major depression, brain morphology and ERK signaling

21 January 2018

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Disrupted-In-Schizophrenia 1 regulates integration of newly generated neurons in the adult brain

21 January 2018

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Recruitment of PCM1 to the centrosome by the cooperative action of DISC1 and BBS4: a candidate for psychiatric illnesses

21 January 2018

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Migration defects by DISC1 knockdown in C57BL/6, 129X1/SvJ, and ICR strains via in utero gene transfer and virus-mediated RNAi

21 January 2018

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Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits

21 January 2018

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Disrupted-in-schizophrenia 1 (DISC1) plays essential roles in mitochondria in collaboration with Mitofilin

21 January 2018

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Development of hippocampal mossy fiber synaptic outputs by new neurons in the adult brain

21 January 2018

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Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1

21 January 2018

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Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality

21 January 2018

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Yeast two-hybrid screens implicate DISC1 in brain development and function

21 January 2018

1 reference

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Disrupted in Schizophrenia 1 (DISC1) is a multicompartmentalized protein that predominantly localizes to mitochondria

21 January 2018

1 reference

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Disrupted in schizophrenia 1 (DISC1): subcellular targeting and induction of ring mitochondria.

21 January 2018

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Metaplasticity: the plasticity of synaptic plasticity

21 January 2018

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Glia-derived D-serine controls NMDA receptor activity and synaptic memory

21 January 2018

1 reference

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BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency-response curve of synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

A CSF and postmortem brain study of D-serine metabolic parameters in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Identification of multiple serine racemase (SRR) mRNA isoforms and genetic analyses of SRR and DAO in schizophrenia and D-serine levels

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Changes in plasma glycine, L-serine, and D-serine levels in patients with schizophrenia as their clinical symptoms improve: results from the Juntendo University Schizophrenia Projects (JUSP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Brain-derived neurotrophic factor: findings in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Pregnenolone, dehydroepiandrosterone, and schizophrenia: alterations and clinical trials.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Impulsivity, aggression and suicide risk among male schizophrenia patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Mental disorder and violence: personality dimensions and clinical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Effectiveness of clozapine versus olanzapine, quetiapine, and risperidone in patients with chronic schizophrenia who did not respond to prior atypical antipsychotic treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Changes in sensorimotor inhibition across the menstrual cycle: implications for neuropsychiatric disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Enhanced dopamine function in DISC1-L100P mutant mice: implications for schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Alterations of dopamine and serotonin transmission in schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Altered psychomotor behaviors in mice lacking pituitary adenylate cyclase-activating polypeptide (PACAP).

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

A novel ES cell line, TT2, with high germline-differentiating potency

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Nectin: an adhesion molecule involved in formation of synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Neonatal polyI:C treatment in mice results in schizophrenia-like behavioral and neurochemical abnormalities in adulthood.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Combined effect of neonatal immune activation and mutant DISC1 on phenotypic changes in adulthood

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Behavioral abnormality and pharmacologic response in social isolation-reared mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Dopamine D1 receptors regulate protein synthesis-dependent long-term recognition memory via extracellular signal-regulated kinase 1/2 in the prefrontal cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Conditional calcineurin knockout mice exhibit multiple abnormal behaviors related to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

Prostaglandin E receptor EP1 controls impulsive behavior under stress.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400

CRMP-2 induces axons in cultured hippocampal neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FHMG%2FDDR400