(Q48974951)

English

Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS.

scientific article published in March 2005

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scholarly article

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Europe PubMed Central

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9 January 2020

Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS (English)

1 reference

Europe PubMed Central

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9 January 2020

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3

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9 January 2020

6

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9 January 2020

11

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9 January 2020

10

object named as

Amit Bar-Or

1 reference

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9 January 2020

author name string

Tim Magnus

1

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9 January 2020

Bettina Schreiner

2

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9 January 2020

Carolyn Jack

4

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9 January 2020

Hong Guo

5

1 reference

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9 January 2020

Igal Ifergan

7

1 reference

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9 January 2020

Lieping Chen

8

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9 January 2020

Felix Bischof

9

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9 January 2020

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publication date

1 March 2005

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9 January 2020

Journal of Neuroscience

1 reference

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9 January 2020

25

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9 January 2020

10

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9 January 2020

2537-2546

1 reference

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9 January 2020

Activation-induced apoptosis of autoreactive and alloreactive T lymphocytes in the target organ as a major mechanism of tolerance

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

FasL (CD95L, Apo1L) is expressed in the normal rat and human brain: evidence for the existence of an immunological brain barrier.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia induce myelin basic protein-specific T cell anergy or T cell activation, according to their state of activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Brain-immune connection: immuno-regulatory properties of CNS-resident cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In situ tolerance within the central nervous system as a mechanism for preventing autoimmunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The expanding B7 superfamily: increasing complexity in costimulatory signals regulating T cell function

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-L2 is a second ligand for PD-1 and inhibits T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resident and infiltrating central nervous system APCs regulate the emergence and resolution of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oral tolerance in experimental autoimmune neuritis (EAN) of the Lewis rat. II. Adjuvant effects and bystander suppression in P2 peptide-induced EAN

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of costimulatory molecules in autoimmunity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Basic principles of immunological surveillance of the normal central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune function of microglia

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglial phagocytosis of apoptotic inflammatory T cells leads to down-regulation of microglial immune activation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-1:PD-L inhibitory pathway affects both CD4(+) and CD8(+) T cells and is overcome by IL-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The B7 family of ligands and its receptors: new pathways for costimulation and inhibition of immune responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The B7-CD28 superfamily

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and regulation of the PD-L1 immunoinhibitory molecule on microvascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The right place at the right time: novel B7 family members regulate effector T cell responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7 family molecules: novel immunomodulators at the maternal-fetal interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immature, semi-mature and fully mature dendritic cells: which signals induce tolerance or immunity?

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytes are less efficient in the removal of apoptotic lymphocytes than microglia cells: implications for the role of glial cells in the inflamed central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-H1 is expressed by human endothelial cells and suppresses T cell cytokine synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of programmed death 1 ligands by murine T cells and APC

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blockade of programmed death-1 ligands on dendritic cells enhances T cell activation and cytokine production

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-H1 (programmed death-1 ligand) on dendritic cells is involved in the induction and maintenance of T cell anergy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular modeling and functional mapping of B7-H1 and B7-DC uncouple costimulatory function from PD-1 interaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vav1-deficient mice are resistant to MOG-induced experimental autoimmune encephalomyelitis due to impaired antigen priming.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role of the programmed death-1 (PD-1) pathway in regulation of experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human muscle cells express a B7-related molecule, B7-H1, with strong negative immune regulatory potential: a novel mechanism of counterbalancing the immune attack in idiopathic inflammatory myopathies

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Constitutive expression of a costimulatory ligand on antigen-presenting cells in the nervous system drives demyelinating disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression of the B7-related molecule B7-H1 by glioma cells: a potential mechanism of immune paralysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analysis of autoreactive CD4 T cells in experimental autoimmune encephalomyelitis after primary and secondary challenge using MHC class II tetramers

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B7-H1 determines accumulation and deletion of intrahepatic CD8(+) T lymphocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type 2 monocyte and microglia differentiation mediated by glatiramer acetate therapy in patients with multiple sclerosis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biology of adult human microglia in culture: comparisons with peripheral blood monocytes and astrocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PD-L1-deficient mice show that PD-L1 on T cells, antigen-presenting cells, and host tissues negatively regulates T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-beta enhances monocyte and dendritic cell expression of B7-H1 (PD-L1), a strong inhibitor of autologous T-cell activation: relevance for the immune modulatory effect in multiple sclerosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Production of nitrite by neonatal rat microglial cells/brain macrophages

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunity to homologous grafted skin; the fate of skin homografts transplanted to the brain, to subcutaneous tissue, and to the anterior chamber of the eye.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of ameboid microglia isolated from developing mammalian brain.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The origin and mechanism of the allograft reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunologically privileged sites

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic elimination of V beta 8.2+ cells from the central nervous system during recovery from experimental autoimmune encephalomyelitis induced by the passive transfer of V beta 8.2+ encephalitogenic T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nervous tissue as an immune compartment: the dialect of the immune response in the CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of MHC class II-antigens on macrophages and microglia, but not on astrocytes and endothelia in active multiple sclerosis lesions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resident macrophages (ramified microglia) of the adult brown Norway rat central nervous system are constitutively major histocompatibility complex class II positive

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death. A model for T-cell apoptosis in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: a sensor for pathological events in the CNS

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of phenotypic and functional properties of immediately ex vivo and cultured human adult microglia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia stimulate naive T-cell differentiation without stimulating T-cell proliferation

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD40-CD154 interaction and IFN-gamma are required for IL-12 but not prostaglandin E2 secretion by microglia during antigen presentation to Th1 cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/15758163

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.4794-04.2005

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758163%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758163%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15758163%20AND%20SRC:MED&resulttype=core&format=json

9 January 2020

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