(Q49017323)

17 February 2018

title

The long noncoding RNA-ROR promotes the resistance of radiotherapy for human colorectal cancer cells by targeting the p53/miR-145 pathway. (English)

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17 February 2018

Adaptive radiation therapy

main subject

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Pengxiang Yang

1

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17 February 2018

Yue Yang

2

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17 February 2018

Weiwei An

3

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17 February 2018

Jianyu Xu

4

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17 February 2018

Gan Zhang

5

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17 February 2018

Jing Jie

6

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17 February 2018

Qingyuan Zhang

7

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17 February 2018

publication date

3 October 2016

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17 February 2018

Journal of Gastroenterology and Hepatology

published in

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17 February 2018

volume

32

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17 February 2018

issue

4

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17 February 2018

page(s)

837-845

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17 February 2018

The landscape of long noncoding RNAs in the human transcriptome

cites work

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Long noncoding RNAs and human disease

21 January 2018

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Chromatin signature reveals over a thousand highly conserved large non-coding RNAs in mammals

21 January 2018

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Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions

21 January 2018

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Long non-coding RNA expression profiles predict clinical phenotypes in glioma

21 January 2018

1 reference

A large intergenic noncoding RNA induced by p53 mediates global gene repression in the p53 response

21 January 2018

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Cell cycle, oncogenic and tumor suppressor pathways regulate numerous long and macro non-protein-coding RNAs

21 January 2018

1 reference

Large intergenic non-coding RNA-RoR modulates reprogramming of human induced pluripotent stem cells

21 January 2018

1 reference

Endogenous miRNA sponge lincRNA-RoR regulates Oct4, Nanog, and Sox2 in human embryonic stem cell self-renewal

21 January 2018

1 reference

Repressing the repressor: a lincRNA as a MicroRNA sponge in embryonic stem cell self-renewal

21 January 2018

1 reference

The human long non-coding RNA-RoR is a p53 repressor in response to DNA damage

21 January 2018

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Modulation of hypoxia-signaling pathways by extracellular linc-RoR.

21 January 2018

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LincRNA-ROR induces epithelial-to-mesenchymal transition and contributes to breast cancer tumorigenesis and metastasis

21 January 2018

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lincRNA-RoR and miR-145 regulate invasion in triple-negative breast cancer via targeting ARF6.

21 January 2018

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Regulation of MDM2 Stability After DNA Damage

21 January 2018

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Functional repair of p53 mutation in colorectal cancer cells using trans-splicing

21 January 2018

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Calbindin 2 (CALB2) regulates 5-fluorouracil sensitivity in colorectal cancer by modulating the intrinsic apoptotic pathway

21 January 2018

1 reference

A positive feedback between p53 and miR-34 miRNAs mediates tumor suppression.

21 January 2018

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p53 represses c-Myc through induction of the tumor suppressor miR-145

21 January 2018

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MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis

21 January 2018

1 reference

Glucocorticoid regulation of a novel HPV-E6-p53-miR-145 pathway modulates invasion and therapy resistance of cervical cancer cells.

21 January 2018

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Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop.

21 January 2018

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miR-145 participates with TP53 in a death-promoting regulatory loop and targets estrogen receptor-alpha in human breast cancer cells

21 January 2018

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Systematic analysis of microRNA expression of RNA extracted from fresh frozen and formalin-fixed paraffin-embedded samples

21 January 2018

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Linc-RNA-RoR acts as a "sponge" against mediation of the differentiation of endometrial cancer stem cells by microRNA-145.

21 January 2018

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NRF2/long noncoding RNA ROR signaling regulates mammary stem cell expansion and protects against estrogen genotoxicity

21 January 2018

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Novel structurally similar chromene derivatives with opposing effects on p53 and apoptosis mechanisms in colorectal HCT116 cancer cells.

21 January 2018

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Cancer stem-like cell characteristics induced by EB virus-encoded LMP1 contribute to radioresistance in nasopharyngeal carcinoma by suppressing the p53-mediated apoptosis pathway

21 January 2018

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The emerging role of hypoxia-inducible factor-2 involved in chemo/radioresistance in solid tumors

21 January 2018

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MicroRNA-145 contributes to enhancing radiosensitivity of cervical cancer cells

21 January 2018

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IL-17 induces radiation resistance of B lymphoma cells by suppressing p53 expression and thereby inhibiting irradiation-triggered apoptosis

21 January 2018

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PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer.

21 January 2018

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Augmentation of response to chemotherapy by microRNA-506 through regulation of RAD51 in serous ovarian cancers

21 January 2018

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Unique characteristics of radiation-induced apoptosis in the postnatally developing small intestine and colon of mice.

21 January 2018

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Li-Fraumeni syndrome fibroblasts homozygous for p53 mutations are deficient in global DNA repair but exhibit normal transcription-coupled repair and enhanced UV resistance

21 January 2018

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p53 responsive nucleotide excision repair gene products p48 and XPC, but not p53, localize to sites of UV-irradiation-induced DNA damage, in vivo

21 January 2018

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Integral role of Noxa in p53-mediated apoptotic response

21 January 2018

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P53 deficiency-induced Smad1 upregulation suppresses tumorigenesis and causes chemoresistance in colorectal cancers

21 January 2018

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21 January 2018

Identifiers

DOI

10.1111/JGH.13606

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17 February 2018

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17 February 2018