(Q49178791)

18 February 2018

review article

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title

The Role of Ferroptosis in Cancer Development and Treatment Response. (English)

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18 February 2018

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Bin Lu

1

1 reference

18 February 2018

Xiao Bing Chen

2

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18 February 2018

Mei Dan Ying

3

1 reference

18 February 2018

Qiao Jun He

4

1 reference

18 February 2018

Ji Cao

5

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18 February 2018

Bo Yang

6

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18 February 2018

publication date

1 January 2017

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18 February 2018

Frontiers in Pharmacology

published in

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18 February 2018

volume

8

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18 February 2018

page(s)

992

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18 February 2018

Creative Commons Attribution 4.0 International

copyright license

start time

12 January 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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22 May 2018

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Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells

22 May 2018

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Induction of ferroptotic cell death for overcoming cisplatin resistance of head and neck cancer

22 May 2018

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Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells

22 May 2018

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The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents

22 May 2018

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Autophagy promotes ferroptosis by degradation of ferritin

22 May 2018

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Metallothionein-1 as a biomarker of altered redox metabolism in hepatocellular carcinoma cells exposed to sorafenib.

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Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis.

22 May 2018

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22 May 2018

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Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells

22 May 2018

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Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate

22 May 2018

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Ferroptosis: process and function

22 May 2018

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22 May 2018

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Regulators of Iron Homeostasis: New Players in Metabolism, Cell Death, and Disease

22 May 2018

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Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells.

22 May 2018

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Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death

22 May 2018

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Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

22 May 2018

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The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis

22 May 2018

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Loss of cysteinyl-tRNA synthetase (CARS) induces the transsulfuration pathway and inhibits ferroptosis induced by cystine deprivation

22 May 2018

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Glutaminolysis and Transferrin Regulate Ferroptosis

22 May 2018

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Identification of artesunate as a specific activator of ferroptosis in pancreatic cancer cells

22 May 2018

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Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

22 May 2018

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Ferroptosis as a p53-mediated activity during tumour suppression

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

HSPB1 as a novel regulator of ferroptotic cancer cell death

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Erastin sensitizes glioblastoma cells to temozolomide by restraining xCT and cystathionine-γ-lyase function

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

22 May 2018

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Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Parthanatos: mitochondrial-linked mechanisms and therapeutic opportunities

22 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Regulation of ferroptotic cancer cell death by GPX4

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

New biological perspectives for the improvement of the efficacy of sorafenib in hepatocellular carcinoma

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Caspase-independent cell death is involved in the negative effect of EGF receptor inhibitors on cisplatin in non-small cell lung cancer cells.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Ferroptosis: an iron-dependent form of nonapoptotic cell death

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Development of small-molecule probes that selectively kill cells induced to express mutant RAS

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

System xc⁻ cystine/glutamate antiporter: an update on molecular pharmacology and roles within the CNS.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-RAS-harboring cancer cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

The roles of therapy-induced autophagy and necrosis in cancer treatment

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Heat shock protein 27 downregulates the transferrin receptor 1-mediated iron uptake

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

The role of autophagy in cancer development and response to therapy.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Redox imbalance in cystine/glutamate transporter-deficient mice

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Apoptosis defects and chemotherapy resistance: molecular interaction maps and networks

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

The selenoprotein GPX4 is essential for mouse development and protects from radiation and oxidative damage insults

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Apoptosis. Its significance in cancer and cancer therapy

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

HMGB1-induced autophagy promotes chemotherapy resistance in leukemia cells.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5770584

Microcytic hypochromic anemia associated with renal cell carcinoma

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29375387

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Unraveling the role of autophagy in cancer

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29375387

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.3389/FPHAR.2017.00992

1 reference

18 February 2018

PMC publication ID

5770584

1 reference

18 February 2018

PubMed publication ID

29375387

1 reference

18 February 2018