(Q49547506)

http://europepmc.org/abstract/MED/29186684

21 February 2018

title

Pancreatic Adenocarcinoma Therapeutic Targets Revealed by Tumor-Stroma Cross-Talk Analyses in Patient-Derived Xenografts. (English)

1 reference

http://europepmc.org/abstract/MED/29186684

21 February 2018

1 reference

1 reference

pancreatic adenocarcinoma

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Yuna Blum

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jean-Marie Boher

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jean Robert Delpero

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Fabienne Guillaumond

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Nelson Dusetti

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

19

Gwen Lomberk

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

author name string

Laetitia Marisa

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Celine Loncle

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Odile Gayet

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Vincent Moutardier

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Olivier Turrini

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Marc Giovannini

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Benjamin Bian

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Martin Bigonnet

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Marion Rubis

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Nabila Elarouci

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Lucile Armenoult

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Mira Ayadi

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Pauline Duconseil

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Mohamed Gasmi

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Mehdi Ouaissi

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Aurélie Maignan

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jacques Ewald

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Erwan Bories

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jonathan Garnier

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Anthony Goncalves

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Flora Poizat

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Jean-Luc Raoul

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Veronique Secq

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Stephane Garcia

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Philippe Grandval

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Marine Barraud-Blanc

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Emmanuelle Norguet

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Marine Gilabert

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Julie Roques

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Ezequiel Calvo

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Sophie Vasseur

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Raul Urrutia

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Aurélien de Reyniès

39

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

Juan Iovanna

41

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

publication date

1 November 2017

1 reference

http://europepmc.org/abstract/MED/29186684

21 February 2018

published in

Cell Reports

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

volume

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

page(s)

2458-2470

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

Integrated Genomic Characterization of Pancreatic Ductal Adenocarcinoma.

11 June 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Pancreatic cancer cell lines as patient-derived avatars: genetic characterisation and functional utility

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Influence of Statins and Cholesterol on Mortality Among Patients With Pancreatic Cancer.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Integrated Patient-Derived Models Delineate Individualized Therapeutic Vulnerabilities of Pancreatic Cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

The Public Repository of Xenografts Enables Discovery and Randomized Phase II-like Trials in Mice

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Anti-stromal treatment together with chemotherapy targets multiple signalling pathways in pancreatic adenocarcinoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Molecular characterization of colorectal cancer patients and concomitant patient-derived tumor cell establishment

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Genomic analyses identify molecular subtypes of pancreatic cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

CYP3A5 mediates basal and acquired therapy resistance in different subtypes of pancreatic ductal adenocarcinoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Matrix control of pancreatic cancer: New insights into fibronectin signaling

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

The consensus molecular subtypes of colorectal cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Development and Characterization of Bladder Cancer Patient-Derived Xenografts for Molecularly Guided Targeted Therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Metabolite profiling stratifies pancreatic ductal adenocarcinomas into subtypes with distinct sensitivities to metabolic inhibitors

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Impact of statin use on survival in patients undergoing resection for early-stage pancreatic cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Enhancing metabolomics research through data mining

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Association between cholesterol intake and pancreatic cancer risk: evidence from a meta-analysis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Statin use and risk of pancreatic cancer: results from a large, clinic-based case-control study

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Stromal SLIT2 impacts on pancreatic cancer-associated neural remodeling

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Vitamin D receptor-mediated stromal reprogramming suppresses pancreatitis and enhances pancreatic cancer therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Transcriptional dissection of pancreatic tumors engrafted in mice.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Genome-wide DNA methylation patterns in pancreatic ductal adenocarcinoma reveal epigenetic deregulation of SLIT-ROBO, ITGA2 and MET signaling.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

RNA-Seq Differentiates Tumour and Host mRNA Expression Changes Induced by Treatment of Human Tumour Xenografts with the VEGFR Tyrosine Kinase Inhibitor Cediranib

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Gene expression classification of colon cancer into molecular subtypes: characterization, validation, and prognostic value

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Tumor-stromal interactions in pancreatic cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Obesity-dependent metabolic signatures associated with nonalcoholic fatty liver disease progression

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Nodal/Activin signaling drives self-renewal and tumorigenicity of pancreatic cancer stem cells and provides a target for combined drug therapy.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Liquid chromatography-mass spectrometry-based parallel metabolic profiling of human and mouse model serum reveals putative biomarkers associated with the progression of nonalcoholic fatty liver disease

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Tumor-derived pancreatic stellate cells promote pancreatic cancer cell invasion through release of thrombospondin-2.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Activin A is an autocrine activator of rat pancreatic stellate cells: potential therapeutic role of follistatin for pancreatic fibrosis

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles.

26 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6082139

Hypermethylation of multiple genes in pancreatic adenocarcinoma

26 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29186684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Co-cultivation of pancreatic cancer cells with orthotopic tumor-derived fibroblasts: fibroblasts stimulate tumor cell invasion via HGF secretion whereas cancer cells exert a minor regulative effect on fibroblasts HGF production

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29186684

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELREP.2017.11.003

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29186684%20AND%20SRC:MED&resulttype=core&format=json

11 June 2020

1 reference