(Q50034376)

23 February 2018

title

LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. (English)

1 reference

23 February 2018

main subject

Apolipoprotein E

1 reference

Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

20

Bartosz Chmielowski

1 reference

23 February 2018

22

Antoni Ribas

1 reference

23 February 2018

23

Daniel Mucida

1 reference

23 February 2018

5

Bernardo S Reis

1 reference

23 February 2018

Masoud F Tavazoie

1

1 reference

23 February 2018

Ilana Pollack

2

1 reference

23 February 2018

Raissa Tanqueco

3

1 reference

23 February 2018

Benjamin N Ostendorf

4

1 reference

23 February 2018

Foster C Gonsalves

6

1 reference

23 February 2018

Isabel Kurth

7

1 reference

23 February 2018

Celia Andreu-Agullo

8

1 reference

23 February 2018

Mark L Derbyshire

9

1 reference

23 February 2018

Jessica Posada

10

1 reference

23 February 2018

Shugaku Takeda

11

1 reference

23 February 2018

Kimia N Tafreshian

12

1 reference

23 February 2018

Eric Rowinsky

13

1 reference

23 February 2018

Michael Szarek

14

1 reference

23 February 2018

Roger J Waltzman

15

1 reference

23 February 2018

Elizabeth A Mcmillan

16

1 reference

23 February 2018

Connie Zhao

17

1 reference

23 February 2018

Monica Mita

18

1 reference

23 February 2018

Alain Mita

19

1 reference

23 February 2018

Michael A Postow

21

1 reference

23 February 2018

Sohail F Tavazoie

24

1 reference

23 February 2018

language of work or name

English

0 references

publication date

9 January 2018

1 reference

23 February 2018

published in

Cell

1 reference

23 February 2018

Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade.

cites work

1 reference

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GITR ligand fusion protein agonist enhances the tumor antigen-specific CD8 T-cell response and leads to long-lasting memory.

8 September 2018

1 reference

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Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

T-cell invigoration to tumour burden ratio associated with anti-PD-1 response.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

T cell costimulatory receptor CD28 is a primary target for PD-1-mediated inhibition.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

The Principles of Engineering Immune Cells to Treat Cancer

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Primary, Adaptive, and Acquired Resistance to Cancer Immunotherapy

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

CD19-Targeted CAR T cells as novel cancer immunotherapy for relapsed or refractory B-cell acute lymphoblastic leukemia

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

An LXR-Cholesterol Axis Creates a Metabolic Co-Dependency for Brain Cancers

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Regulatory T Cells: Differentiation and Function

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

A clinical and biological perspective of human myeloid-derived suppressor cells in cancer

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Vaccination during myeloid cell depletion by cancer chemotherapy fosters robust T cell responses

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Phase I/II Study of Metastatic Melanoma Patients Treated with Nivolumab Who Had Progressed after Ipilimumab.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Liver X receptors in immune cell function in humans.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Targeting liver X receptors in cancer therapeutics

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Cholesterol, inflammation and innate immunity

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

PD-1 blockade induces responses by inhibiting adaptive immune resistance

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Anti-inflammatory and cholesterol-reducing properties of apolipoprotein mimetics: a review

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Liver X receptors alpha gene (NR1H3) promoter polymorphisms are associated with systemic lupus erythematosus in Koreans

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Liver X receptors in lipid metabolism: opportunities for drug discovery

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Liver X receptor gene polymorphisms in tuberculosis: effect on susceptibility

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Nuclear Receptors, RXR, and the Big Bang

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

PD-1 identifies the patient-specific CD8⁺ tumor-reactive repertoire infiltrating human tumors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Frequencies of circulating MDSC correlate with clinical outcome of melanoma patients treated with ipilimumab

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Coordinated regulation of myeloid cells by tumours

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Coordinate regulation of neutrophil homeostasis by liver X receptors in mice

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Cross-talk between apolipoprotein E and cytokines

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Lipoprotein receptors--an evolutionarily ancient multifunctional receptor family

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Increased intensity lymphodepletion enhances tumor treatment efficacy of adoptively transferred tumor-specific T cells

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Tumor vaccines expressing flt3 ligand synergize with ctla-4 blockade to reject preimplanted tumors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Subsets of myeloid-derived suppressor cells in tumor-bearing mice

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

PD-1 and PD-1 ligands: from discovery to clinical application

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

PD-1 blockade inhibits hematogenous spread of poorly immunogenic tumor cells by enhanced recruitment of effector T cells

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Regulation of immune mechanisms in atherosclerosis.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Oxysterol activators of liver X receptor and 9-cis-retinoic acid promote sequential steps in the synthesis and secretion of tumor necrosis factor-alpha from human monocytes

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

gp100/pmel 17 is a murine tumor rejection antigen: induction of "self"-reactive, tumoricidal T cells using high-affinity, altered peptide ligand

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Enhancement of antitumor immunity by CTLA-4 blockade

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

LXR, a nuclear receptor that defines a distinct retinoid response pathway

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Broad-spectrum therapeutic suppression of metastatic melanoma through nuclear hormone receptor activation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Liver X Receptor Activation Potentiates the Lipopolysaccharide Response in Human Macrophages

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5846344

Increased production of immature myeloid cells in cancer patients: a mechanism of immunosuppression in cancer

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29336888

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cross-talk between myeloid-derived suppressor cells and macrophages subverts tumor immunity toward a type 2 response

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29336888

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Treg Cells Survive and Thrive in Inhospitable Environments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29336888

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2017.12.026

1 reference

23 February 2018

0 references

1 reference

23 February 2018