(Q50045161)

24 February 2018

http://europepmc.org/abstract/MED/29436396

title

Rapid activation of tumor-associated macrophages boosts preexisting tumor immunity. (English)

1 reference

24 February 2018

http://europepmc.org/abstract/MED/29436396

author

Sabine Hoves

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Chia Huey Ooi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Stefan Bissinger

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Martina Schmittnaegel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Oliver Ast

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Katharina Wartha

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Valeria Runza

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hyam Levitsky

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Solange Romagnoli

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Michele De Palma

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Carola H Ries

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

12

Yvonne Kienast

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

Carsten Wolter

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hadassah Sade

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Anna M Giusti

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Wei Xu

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Michael A Cannarile

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Dominik Rüttinger

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

7 February 2018

1 reference

24 February 2018

http://europepmc.org/abstract/MED/29436396

published in

Journal of Experimental Medicine

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

215

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

859-876

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

Myeloid-targeted immunotherapies act in synergy to induce inflammation and antitumor immunity.

2 June 2020

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1 reference

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Combination of CD40 Agonism and CSF-1R Blockade Reconditions Tumor-Associated Macrophages and Drives Potent Antitumor Immunity.

29 September 2018

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Regulation of myeloid cells by activated T cells determines the efficacy of PD-1 blockade.

29 September 2018

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Tumour-associated macrophages as treatment targets in oncology.

29 September 2018

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Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells.

29 September 2018

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Regulation and Immune Function of IL-27.

29 September 2018

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PI3Kγ is a molecular switch that controls immune suppression

29 September 2018

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Perivascular Macrophages Limit Permeability

29 September 2018

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Timing of CSF-1/CSF-1R signaling blockade is critical to improving responses to CTLA-4 based immunotherapy.

29 September 2018

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Novel human IgG1 and IgG4 Fc-engineered antibodies with completely abolished immune effector functions

29 September 2018

1 reference

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Suppression of microRNA activity amplifies IFN-γ-induced macrophage activation and promotes anti-tumour immunity.

29 September 2018

1 reference

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Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement

29 September 2018

1 reference

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CSF-1R-Dependent Lethal Hepatotoxicity When Agonistic CD40 Antibody Is Given before but Not after Chemotherapy.

29 September 2018

1 reference

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The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation

29 September 2018

1 reference

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CSF-1/CSF-1R targeting agents in clinical development for cancer therapy.

29 September 2018

1 reference

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Group sparsity model for stain unmixing in brightfield multiplex immunohistochemistry images

29 September 2018

1 reference

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Therapeutic Peptide Vaccine-Induced CD8 T Cells Strongly Modulate Intratumoral Macrophages Required for Tumor Regression.

29 September 2018

1 reference

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Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Macrophages and therapeutic resistance in cancer

29 September 2018

1 reference

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Immune checkpoint blockade: a common denominator approach to cancer therapy

29 September 2018

1 reference

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

PD-1 blockade induces responses by inhibiting adaptive immune resistance

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Targeting tumor-associated macrophages with anti-CSF-1R antibody reveals a strategy for cancer therapy

29 September 2018

1 reference

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CSF-1 receptor signaling in myeloid cells

29 September 2018

1 reference

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Locally delivered CD40 agonist antibody accumulates in secondary lymphoid organs and eradicates experimental disseminated bladder cancer.

29 September 2018

1 reference

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Role of crosslinking for agonistic CD40 monoclonal antibodies as immune therapy of cancer

29 September 2018

1 reference

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Inhibition of CSF-1 receptor improves the antitumor efficacy of adoptive cell transfer immunotherapy

29 September 2018

1 reference

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gCMAP: user-friendly connectivity mapping with R.

29 September 2018

1 reference

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Aging predisposes to acute inflammatory induced pathology after tumor immunotherapy

29 September 2018

1 reference

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CSF-1R inhibition alters macrophage polarization and blocks glioma progression

29 September 2018

1 reference

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Innate and adaptive immune cells in the tumor microenvironment

29 September 2018

1 reference

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A phase I study of an agonist CD40 monoclonal antibody (CP-870,893) in combination with gemcitabine in patients with advanced pancreatic ductal adenocarcinoma

29 September 2018

1 reference

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Specificity through cooperation: BATF-IRF interactions control immune-regulatory networks

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Agonistic CD40 antibodies and cancer therapy

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Neutralizing tumor-promoting chronic inflammation: a magic bullet?

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Genetic programs expressed in resting and IL-4 alternatively activated mouse and human macrophages: similarities and differences

29 September 2018

1 reference

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Prognostic significance of tumor-associated macrophages in solid tumor: a meta-analysis of the literature.

29 September 2018

1 reference

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T-cell-independent antitumor effects of CD40 ligation

29 September 2018

1 reference

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The mouse dendritic cell marker CD11c is down-regulated upon cell activation through Toll-like receptor triggering

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Differentiation and gene expression profile of tumor-associated macrophages

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Digital multiplexed gene expression analysis using the NanoString nCounter system

29 September 2018

1 reference

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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans

29 September 2018

1 reference

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Biology and clinical applications of CD40 in cancer treatment

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

An antibody against the colony-stimulating factor 1 receptor depletes the resident subset of monocytes and tissue- and tumor-associated macrophages but does not inhibit inflammation

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Orphan granzymes find a home

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Alternative activation of macrophages: mechanism and functions

29 September 2018

1 reference

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Cross-regulation of signaling pathways by interferon-gamma: implications for immune responses and autoimmune diseases

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Macrophage CD40 signaling: a pivotal regulator of disease protection and pathogenesis

29 September 2018

1 reference

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Molecular mechanism and function of CD40/CD40L engagement in the immune system.

29 September 2018

1 reference

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Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Synergistic activation of macrophages via CD40 and TLR9 results in T cell independent antitumor effects

29 September 2018

1 reference

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Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Redirecting in vivo elicited tumor infiltrating macrophages and dendritic cells towards tumor rejection.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

The role of the CD40 pathway in the pathogenesis and treatment of cancer.

29 September 2018

1 reference

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Interferon-γ: an overview of signals, mechanisms and functions

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

ICSBP/IRF-8: its regulatory roles in the development of myeloid cells

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

Antitumor effect of CD40 ligand: elicitation of local and systemic antitumor responses by IL-12 and B7.

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

CD40 AND CD154 IN CELL-MEDIATED IMMUNITY

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

T cell immunity to lymphoma following treatment with anti-CD40 monoclonal antibody

29 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

T Cell Cancer Therapy Requires CD40-CD40L Activation of Tumor Necrosis Factor and Inducible Nitric-Oxide-Synthase-Producing Dendritic Cells

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5839760

30 November 2018

Identifiers

DOI

10.1084/JEM.20171440

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29436396%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference