(Q50048770)

http://europepmc.org/abstract/MED/29333574

24 February 2018

title

Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

Robert Cramer

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

5

Mihai G Netea

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

author name string

Lily Boutens

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

Sourabh Dhingra

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

Rinke Stienstra

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

publication date

14 January 2018

1 reference

http://europepmc.org/abstract/MED/29333574

24 February 2018

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Diabetologia

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

volume

61

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

page(s)

942-953

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 May 2020

copyright license

start time

14 January 2018

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

exact match

https://scigraph.springernature.com/pub.10.1007/s00125-017-4526-6

0 references

cites work

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Pro-inflammatory CD11c+CD206+ adipose tissue macrophages are associated with insulin resistance in human obesity

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Alternative activation of macrophages

21 January 2018

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M-1/M-2 macrophages and the Th1/Th2 paradigm

21 January 2018

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Obesity induces a phenotypic switch in adipose tissue macrophage polarization

21 January 2018

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Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages

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Transcriptome-based network analysis reveals a spectrum model of human macrophage activation.

21 January 2018

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Metabolic dysfunction drives a mechanistically distinct proinflammatory phenotype in adipose tissue macrophages

21 January 2018

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Obesity activates a program of lysosomal-dependent lipid metabolism in adipose tissue macrophages independently of classic activation

21 January 2018

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Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization

21 January 2018

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Immunometabolism governs dendritic cell and macrophage function

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Metabolism Supports Macrophage Activation

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HIF1α and metabolic reprogramming in inflammation.

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HIF-1alpha is essential for myeloid cell-mediated inflammation

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Tissue-specific signals control reversible program of localization and functional polarization of macrophages

21 January 2018

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Unravelling mononuclear phagocyte heterogeneity

21 January 2018

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A lineage of myeloid cells independent of Myb and hematopoietic stem cells

21 January 2018

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Keratinocyte-derived chemokine in obesity: expression, regulation, and role in adipose macrophage infiltration and glucose homeostasis

21 January 2018

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Association between measures of insulin sensitivity and circulating levels of interleukin-8, interleukin-6 and tumor necrosis factor-alpha. Effect of weight loss in obese men.

21 January 2018

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Circulating levels of MCP-1 and IL-8 are elevated in human obese subjects and associated with obesity-related parameters

21 January 2018

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Leptin secretion from adipose tissue in women. Relationship to plasma levels and gene expression

21 January 2018

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Participation of leptin in the determination of the macrophage phenotype: an additional role in adipocyte and macrophage crosstalk.

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Metabolism of inflammation limited by AMPK and pseudo-starvation

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A bioenergetic profile of non-transformed fibroblasts uncovers a link between death-resistance and enhanced spare respiratory capacity.

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Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice

21 January 2018

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Adipose tissue macrophages: going off track during obesity

21 January 2018

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Newly identified adipose tissue macrophage populations in obesity with distinct chemokine and chemokine receptor expression.

21 January 2018

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Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice

21 January 2018

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Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

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Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

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Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

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Microbial stimulation of different Toll-like receptor signalling pathways induces diverse metabolic programmes in human monocytes

21 January 2018

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Mitochondrial Respiration Controls Lysosomal Function during Inflammatory T Cell Responses.

21 January 2018

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Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation.

21 January 2018

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Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans

21 January 2018

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HIF-1α in Myeloid Cells Promotes Adipose Tissue Remodeling Toward Insulin Resistance.

21 January 2018

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Increased Inflammatory Properties of Adipose Tissue Macrophages Recruited During Diet-Induced Obesity

21 January 2018

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Lactate production in adipose tissue: a regulated function with extra-adipose implications

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29333574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mannose-Binding Lectin Is Required for the Effective Clearance of Apoptotic Cells by Adipose Tissue Macrophages During Obesity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29333574

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S00125-017-4526-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6448980&resulttype=core&format=json

13 May 2020

1 reference