(Q50059057)

24 February 2018

title

BRCA1 through Its E3 Ligase Activity Regulates the Transcription Factor Oct1 and Carbohydrate Metabolism. (English)

1 reference

24 February 2018

author name string

Karina Vázquez-Arreguín

1

1 reference

24 February 2018

Jessica Maddox

2

1 reference

24 February 2018

Jinsuk Kang

3

1 reference

24 February 2018

Dongju Park

4

1 reference

24 February 2018

Reuben R Cano

5

1 reference

24 February 2018

Rachel E Factor

6

1 reference

24 February 2018

Thomas Ludwig

7

1 reference

24 February 2018

Dean Tantin

8

1 reference

24 February 2018

language of work or name

1 reference

12 January 2018

1 reference

24 February 2018

Molecular Cancer Research

published in

1 reference

24 February 2018

Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal

cites work

1 reference

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Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patients

8 September 2018

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Genome-Wide CRISPR-Cas9 Screen Identifies MicroRNAs That Regulate Myeloid Leukemia Cell Growth

8 September 2018

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Reductive carboxylation supports redox homeostasis during anchorage-independent growth

8 September 2018

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The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks

8 September 2018

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Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling

8 September 2018

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Glucose-based regulation of miR-451/AMPK signaling depends on the OCT1 transcription factor

8 September 2018

1 reference

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Improved vectors and genome-wide libraries for CRISPR screening

8 September 2018

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BRCA1 induces major energetic metabolism reprogramming in breast cancer cells.

8 September 2018

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VEGFR3 inhibition chemosensitizes ovarian cancer stemlike cells through down-regulation of BRCA1 and BRCA2.

8 September 2018

1 reference

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OCT1 is a determinant of synbindin-related ERK signalling with independent prognostic significance in gastric cancer

8 September 2018

1 reference

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Incidence of colorectal cancer in BRCA1 and BRCA2 mutation carriers: results from a follow-up study

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Oct transcription factors in development and stem cells: insights and mechanisms

8 September 2018

1 reference

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Clinical-pathologic significance of cancer stem cell marker expression in familial breast cancers

8 September 2018

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Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

STAT3 is involved in esophageal carcinogenesis through regulation of Oct-1.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Transcription factor Oct1 is a somatic and cancer stem cell determinant

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

A DNA-damage selective role for BRCA1 E3 ligase in claspin ubiquitylation, CHK1 activation, and DNA repair.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Oncosecretomics coupled to bioenergetics identifies α-amino adipic acid, isoleucine and GABA as potential biomarkers of cancer: Differential expression of c-Myc, Oct1 and KLF4 coordinates metabolic changes

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

The Lgr5 intestinal stem cell signature: robust expression of proposed quiescent '+4' cell markers

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

A novel role for BRCA1 in regulating breast cancer cell spreading and motility

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Oct1 is a switchable, bipotential stabilizer of repressed and inducible transcriptional states.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 down-regulates cellular levels of reactive oxygen species

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Oct1 loss of function induces a coordinate metabolic shift that opposes tumorigenicity.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Lamin B1 controls oxidative stress responses via Oct-1.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

E3 ligase activity of BRCA1 is not essential for mammalian cell viability or homology-directed repair of double-strand DNA breaks

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA germline mutations in Jewish patients with pancreatic adenocarcinoma

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 regulates human mammary stem/progenitor cell fate

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer.

8 September 2018

1 reference

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ATF-2 controls transcription of Maspin and GADD45 alpha genes independently from p53 to suppress mammary tumors

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 ubiquitinates its phosphorylation-dependent binding partner CtIP

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

The octamer binding transcription factor Oct-1 is a stress sensor

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 induces antioxidant gene expression and resistance to oxidative stress

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1-dependent ubiquitination of gamma-tubulin regulates centrosome number

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Down-regulation of BRCA1 in chronic pancreatitis and sporadic pancreatic adenocarcinoma

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

The BRCA1/BARD1 heterodimer assembles polyubiquitin chains through an unconventional linkage involving lysine residue K6 of ubiquitin

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Enhancement of BRCA1 E3 ubiquitin ligase activity through direct interaction with the BARD1 protein

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BARD1 induces BRCA1 intranuclear foci formation by increasing RING-dependent BRCA1 nuclear import and inhibiting BRCA1 nuclear export

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

BRCA1 regulates GADD45 through its interactions with the OCT-1 and CAAT motifs

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Cancer-predisposing mutations within the RING domain of BRCA1: loss of ubiquitin protein ligase activity and protection from radiation hypersensitivity

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Crystal structure of the Oct-1 POU domain bound to an octamer site: DNA recognition with tethered DNA-binding modules

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Methylation of the BRCA1 gene in sporadic breast cancer

8 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Germline BRCA1 mutations predispose to pancreatic adenocarcinoma

2 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5835178

Decreased expression of BRCA1 accelerates growth and is often present during sporadic breast cancer progression

30 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/29330289

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/1541-7786.MCR-17-0364

1 reference

24 February 2018

PMC publication ID

5835178

0 references

1 reference

24 February 2018