(Q50074773)

http://europepmc.org/abstract/PMC/6011627

8 July 2018

title

Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability. (English)

1 reference

http://europepmc.org/abstract/PMC/6011627

8 July 2018

author

Ryan Patel

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Damini Tewari

29

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Gary Lewin

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Greg A Weir

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Steven J Middleton

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Kim I Chisholm

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Liam J Peck

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Alex J Clark

18

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Andreas C Themistocleous

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Teodora Trendafilova

24

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

David A Menassa

25

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Maria Pia Giannoccaro

26

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ilaria Cervellini

28

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hanns Ulrich Zeilhofer

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Elior Peles

34

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Stephen B. McMahon

36

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

David L Bennett

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

12

Jorge Galino

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

39

Angela Vincent

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

author name string

John M Dawes

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Philippa Pettingill

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Joseph Sheridan

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Akila Shakir

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Leslie Jacobson

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Maria Gutierrez-Mecinas

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Jan Walcher

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Johannes Kühnemund

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hannah Kuehn

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Maria D Sanna

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Bethan Lang

17

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Noboru Iwagaki

20

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Steven J West

21

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Karolina Werynska

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Liam Carroll

23

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Ester Coutinho

27

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Camilla Buckley

30

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

M Isabel Leite

31

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Hendrik Wildner

32

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Andrew J Todd

35

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

Anthony H Dickenson

37

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

language of work or name

English

0 references

publication date

8 February 2018

1 reference

http://europepmc.org/abstract/PMC/6011627

8 July 2018

published in

Neuron

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

volume

97

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

page(s)

806-822.e10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

2 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC6011627/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Persistent microglial activation and synaptic loss with behavioral abnormalities in mouse offspring exposed to CASPR2-antibodies in utero.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Mechanisms of Autoantibody-Induced Pathology.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Identification of spinal circuits involved in touch-evoked dynamic mechanical pain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Dorsal root ganglion neurons become hyperexcitable and increase expression of voltage-gated T-type calcium channels (Cav3.2) in paclitaxel-induced peripheral neuropathy.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Voltage-gated potassium channel-complex autoimmunity and associated clinical syndromes

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Altered potassium channel distribution and composition in myelinated axons suppresses hyperexcitability following injury.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Caspr2 autoantibodies target multiple epitopes.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Crosstalk between the nociceptive and immune systems in host defence and disease

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

A long noncoding RNA contributes to neuropathic pain by silencing Kcna2 in primary afferent neurons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Shining a light on CNTNAP2: complex functions to complex disorders

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Kv1.1 channels act as mechanical brake in the senses of touch and pain

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Chronic pain as a manifestation of potassium channel-complex autoimmunity

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Morvan syndrome: clinical and serological observations in 29 cases

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

The functional organization of cutaneous low-threshold mechanosensory neurons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Unmyelinated and myelinated skin nerve damage in Guillain-Barré syndrome: correlation with pain and recovery.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Somatosensory processing in neurodevelopmental disorders

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Investigations of caspr2, an autoantigen of encephalitis and neuromyotonia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Antibodies to Kv1 potassium channel-complex proteins leucine-rich, glioma inactivated 1 protein and contactin-associated protein-2 in limbic encephalitis, Morvan's syndrome and acquired neuromyotonia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Multiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Recessive symptomatic focal epilepsy and mutant contactin-associated protein-like 2

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Glycinergic neurons expressing enhanced green fluorescent protein in bacterial artificial chromosome transgenic mice

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Juxtaparanodal clustering of Shaker-like K+ channels in myelinated axons depends on Caspr2 and TAG-1

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

A T-type calcium channel required for normal function of a mammalian mechanoreceptor

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Distinct potassium channels on pain-sensing neurons

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Quantitative assessment of tactile allodynia in the rat paw

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

miR-183 cluster scales mechanical pain sensitivity by regulating basal and neuropathic pain genes.

10 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Touch Receptor-Derived Sensory Information Alleviates Acute Pain Signaling and Fine-Tunes Nociceptive Reflex Coordination.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

SHANK3 Deficiency Impairs Heat Hyperalgesia and TRPV1 Signaling in Primary Sensory Neurons

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Contactin-1 IgG4 antibodies cause paranode dismantling and conduction defects.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Expression of Cntnap2 (Caspr2) in multiple levels of sensory systems.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

A somatosensory circuit for cooling perception in mice.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

The interphase of the formalin test.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

A CRPS-IgG-transfer-trauma model reproducing inflammatory and positive sensory signs associated with complex regional pain syndrome

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Variable threshold of trigeminal cold-thermosensitive neurons is determined by a balance between TRPM8 and Kv1 potassium channels.

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Characterization of six voltage-gated K+ currents in adult rat sensory neurons

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

On the role of nerve growth factor in the development of myelinated nociceptors

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=6011627

Potassium channel distribution, clustering, and function in remyelinating rat axons

2 November 2018

1 reference

12 December 2020

Activating transcription factor 3 (ATF3) induction by axotomy in sensory and motoneurons: A novel neuronal marker of nerve injury

1 reference

12 December 2020

Manipulation of the potassium channel Kv1.1 and its effect on neuronal excitability in rat sensory neurons

1 reference

12 December 2020

Motor coordination and balance in rodents

1 reference

12 December 2020

10.1016/J.NEURON.2018.01.033

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

release_acvl5l3zove5dg3bqjb5dnmnua

2 June 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/acvl5l3zove5dg3bqjb5dnmnua

24 November 2022

mapped directly with Wikidata item

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29429934%20AND%20SRC:MED&resulttype=core&format=json

2 June 2020

1 reference