(Q50116964)

25 February 2018

http://europepmc.org/abstract/MED/29316433

title

TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. (English)

1 reference

25 February 2018

http://europepmc.org/abstract/MED/29316433

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

Alycia Gardner

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

Brian Ruffell

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

5

Hope S Rugo

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

author name string

Shandi Hiebler

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

Hatem Soliman

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

Matthew F Krummel

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

Lisa M Coussens

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

publication date

1 January 2018

1 reference

25 February 2018

http://europepmc.org/abstract/MED/29316433

published in

Cancer Cell

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

issue

1

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

page(s)

60-74.e6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

Induction of mammary tumors by expression of polyomavirus middle T oncogene: a transgenic mouse model for metastatic disease

14 May 2020

cites work

1 reference

12 December 2020

Prostate and mammary adenocarcinoma in transgenic mice carrying a rat C3(1) simian virus 40 large tumor antigen fusion gene

1 reference

12 December 2020

Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease

1 reference

12 December 2020

The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity

1 reference

12 December 2020

Antagonism of CXCR3 inhibits lung metastasis in a murine model of metastatic breast cancer

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12 December 2020

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer.

1 reference

12 December 2020

Preferential involvement of Tim-3 in the regulation of hepatic CD8+ T cells in murine acute graft-versus-host disease

1 reference

12 December 2020

A highly conserved tyrosine of Tim-3 is phosphorylated upon stimulation by its ligand galectin-9

1 reference

12 December 2020

Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma

1 reference

12 December 2020

Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells

1 reference

12 December 2020

Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

1 reference

12 December 2020

Batf3 Deficiency Reveals a Critical Role for CD8 + Dendritic Cells in Cytotoxic T Cell Immunity

1 reference

12 December 2020

Tim-3 mediates phagocytosis of apoptotic cells and cross-presentation

1 reference

12 December 2020

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

1 reference

12 December 2020

T cell Ig and mucin domain proteins and immunity

1 reference

12 December 2020

Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

1 reference

12 December 2020

Upregulation of Tim-3 and PD-1 expression is associated with tumor antigen–specific CD8+ T cell dysfunction in melanoma patients

1 reference

12 December 2020

Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

1 reference

12 December 2020

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

1 reference

12 December 2020

Galectin-9 regulates T helper cell function independently of Tim-3.

1 reference

12 December 2020

Anti-TIM3 antibody promotes T cell IFN-γ-mediated antitumor immunity and suppresses established tumors

1 reference

12 December 2020

Exhaustion of tumor-specific CD8⁺ T cells in metastases from melanoma patients

1 reference

12 December 2020

Id2 expression delineates differential checkpoints in the genetic program of CD8α+ and CD103+ dendritic cell lineages

1 reference

12 December 2020

Phosphotyrosine-dependent coupling of Tim-3 to T-cell receptor signaling pathways.

1 reference

12 December 2020

Leukocyte composition of human breast cancer

1 reference

12 December 2020

CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen

1 reference

12 December 2020

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

1 reference

12 December 2020

Galectin-9 and T cell immunoglobulin mucin-3 pathway is a therapeutic target for type 1 diabetes.

1 reference

12 December 2020

The immune contexture in human tumours: impact on clinical outcome

1 reference

12 December 2020

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells

1 reference

12 December 2020

Tumor-infiltrating DCs suppress nucleic acid-mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

1 reference

12 December 2020

Bat3 promotes T cell responses and autoimmunity by repressing Tim-3–mediated cell death and exhaustion.

1 reference

12 December 2020

Comprehensive molecular portraits of human breast tumours

1 reference

12 December 2020

Combined blockade of TIM-3 and TIM-4 augments cancer vaccine efficacy against established melanomas.

1 reference

12 December 2020

Immunogenic cell death in cancer therapy

1 reference

12 December 2020

CD8α+ DCs can be induced in the absence of transcription factors Id2, Nfil3, and Batf3.

1 reference

12 December 2020

Peripheral prepositioning and local CXCL9 chemokine-mediated guidance orchestrate rapid memory CD8+ T cell responses in the lymph node

1 reference

12 December 2020

TIM-3 does not act as a receptor for galectin-9.

1 reference

12 December 2020

Oncology meets immunology: the cancer-immunity cycle

1 reference

12 December 2020

Signatures of mutational processes in human cancer

1 reference

12 December 2020

Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy

1 reference

12 December 2020

Tim-3 directly enhances CD8 T cell responses to acute Listeria monocytogenes infection

1 reference

12 December 2020

T cell memory. A local macrophage chemokine network sustains protective tissue-resident memory CD4 T cells

1 reference

12 December 2020

Immunoregulation of dendritic cells by the receptor T cell Ig and mucin protein-3 via Bruton's tyrosine kinase and c-Src

1 reference

12 December 2020

The evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer: recommendations by an International TILs Working Group 2014.

1 reference

12 December 2020

Perivascular leukocyte clusters are essential for efficient activation of effector T cells in the skin.

1 reference

12 December 2020

Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy

1 reference

12 December 2020

Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

1 reference

12 December 2020

PD-1 blockade induces responses by inhibiting adaptive immune resistance

1 reference

12 December 2020

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing.

1 reference

12 December 2020

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells

1 reference

12 December 2020

Dissecting the tumor myeloid compartment reveals rare activating antigen-presenting cells critical for T cell immunity

1 reference

12 December 2020

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

1 reference

12 December 2020

Immune-mediated mechanisms influencing the efficacy of anticancer therapies.

1 reference

12 December 2020

Melanoma-intrinsic β-catenin signalling prevents anti-tumour immunity

1 reference

12 December 2020

PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

1 reference

12 December 2020

Batf3 maintains autoactivation of Irf8 for commitment of a CD8α(+) conventional DC clonogenic progenitor.

1 reference

12 December 2020

Randomized Phase III Trial of Paclitaxel Once Per Week Compared With Nanoparticle Albumin-Bound Nab-Paclitaxel Once Per Week or Ixabepilone With Bevacizumab As First-Line Chemotherapy for Locally Recurrent or Metastatic Breast Cancer: CALGB 40502/NC

1 reference

12 December 2020

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

1 reference

12 December 2020

Cancer Immunotherapy with Immunomodulatory Anti-CD137 and Anti-PD-1 Monoclonal Antibodies Requires BATF3-Dependent Dendritic Cells

1 reference

12 December 2020

Tim-3 enhances FcεRI-proximal signaling to modulate mast cell activation

1 reference

12 December 2020

Visualization of immediate immune responses to pioneer metastatic cells in the lung.

1 reference

12 December 2020

Expansion and Activation of CD103(+) Dendritic Cell Progenitors at the Tumor Site Enhances Tumor Responses to Therapeutic PD-L1 and BRAF Inhibition.

1 reference

12 December 2020

Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.

1 reference

12 December 2020

Critical Role for CD103(+)/CD141(+) Dendritic Cells Bearing CCR7 for Tumor Antigen Trafficking and Priming of T Cell Immunity in Melanoma

1 reference

12 December 2020

Tumor-Residing Batf3 Dendritic Cells Are Required for Effector T Cell Trafficking and Adoptive T Cell Therapy

1 reference

12 December 2020

10.1016/J.CCELL.2017.11.019

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC5764109&resulttype=core&format=json

14 May 2020

1 reference