(Q50125755)

25 February 2018

title

Development of a new genotoxicity test system with Salmonella typhimurium OY1001/1A2 expressing human CYP1A2 and NADPH-P450 reductase. (English)

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25 February 2018

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Salmonella Typhimurium

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4

F P Guengerich

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25 February 2018

author name string

P Aryal

1

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25 February 2018

K Yoshikawa

2

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25 February 2018

T Terashita

3

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25 February 2018

T Shimada

5

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25 February 2018

Y Oda

6

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25 February 2018

language of work or name

English

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publication date

1 June 1999

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25 February 2018

published in

Mutation Research

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25 February 2018

volume

442

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25 February 2018

issue

2

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25 February 2018

page(s)

113-120

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25 February 2018

Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes

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Activation of procarcinogens by human cytochrome P450 enzymes

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7 January 2021

Metabolic activation of aromatic amine mutagens by simultaneous expression of human cytochrome P450 1A2, NADPH-cytochrome P450 reductase, and N-acetyltransferase in Escherichia coli.

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7 January 2021

Expression of human cytochrome P450 1A2 in Escherichia coli: a system for biotransformation and genotoxicity studies of chemical carcinogens.

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7 January 2021

Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens

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7 January 2021

Validation of the SOS/Umu test with mutagenic complex mixtures

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7 January 2021

Application of the SOS umu-test in detection of pollution using fish liver S9 fraction.

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7 January 2021

A microplate version of the SOS/umu-test for rapid detection of genotoxins and genotoxic potentials of environmental samples.

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7 January 2021

The evaluation of genotoxic activities of disinfectants and their metabolites by umu test.

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7 January 2021

Mutagenic activity of various kinds of cheese on the Ames, rec and umu assays.

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7 January 2021

A new Salmonella typhimurium NM5004 strain expressing rat glutathione S-transferase 5-5: use in detection of genotoxicity of dihaloalkanes using an SOS/umu test system.

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7 January 2021

Activation and inactivation of carcinogenic dihaloalkanes and other compounds by glutathione S-transferase 5-5 in Salmonella typhimurium tester strain NM5004.

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7 January 2021

Highly sensitive umu test system for the detection of mutagenic nitroarenes in Salmonella typhimurium NM3009 having high O-acetyltransferase and nitroreductase activities.

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7 January 2021

Development of high sensitive umu test system: rapid detection of genotoxicity of promutagenic aromatic amines by Salmonella typhimurium strain NM2009 possessing high O-acetyltransferase activity.

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7 January 2021

An Improved Bacterial Test System for the Detection and Classification of Mutagens and Carcinogens

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7 January 2021

Construction and characterization of amplifiable multicopy DNA cloning vehicles derived from the P15A cryptic miniplasmid

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7 January 2021

The function of recombinant cytochrome P450s in intact Escherichia coli cells: the 17 alpha-hydroxylation of progesterone and pregnenolone by P450c17.

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7 January 2021

Drug metabolism by Escherichia coli expressing human cytochromes P450.

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7 January 2021

Cloning and characterization of the umu operon responsible for inducible mutagenesis in Escherichia coli

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7 January 2021

Expression of modified human cytochrome P450 1A2 in Escherichia coli: stabilization, purification, spectral characterization, and catalytic activities of the enzyme.

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7 January 2021

Role of human N-acetyltransferases, NAT1 or NAT2, in genotoxicity of nitroarenes and aromatic amines in Salmonella typhimurium NM6001 and NM6002.

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https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900070-4

7 January 2021

High catalytic activity of human cytochrome P450 co-expressed with human NADPH-cytochrome P450 reductase in Escherichia coli

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7 January 2021

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.

1 reference

https://api.crossref.org/works/10.1016%2FS1383-5718%2899%2900070-4

7 January 2021

10.1016/S1383-5718(99)00070-4

Identifiers

DOI

1 reference

25 February 2018

1 reference

25 February 2018