(Q50210803)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

title

Caspase-Cleaved Tau Impairs Mitochondrial Dynamics in Alzheimer's Disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

author name string

Katiana Vergara-Pulgar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Claudia Jara

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Fabian Cabezas-Opazo

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

Rodrigo A Quintanilla

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

publication date

13 January 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

published in

Molecular Neurobiology

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

volume

55

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

page(s)

1004-1018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

https://scigraph.springernature.com/pub.10.1007/s12035-017-0385-x

9 April 2020

exact match

0 references

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase-cleavage of tau is an early event in Alzheimer disease tangle pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Glycogen synthase kinase 3 beta induces caspase-cleaved tau aggregation in situ

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase-mediated truncation of tau potentiates aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Soluble hyper-phosphorylated tau causes microtubule breakdown and functionally compromises normal tau in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Hyperphosphorylation and cleavage at D421 enhance tau secretion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

GRK5 dysfunction accelerates tau hyperphosphorylation in APP (swe) mice through impaired cholinergic activity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Differential regulation of dynein and kinesin motor proteins by tau

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Truncated tau and Aβ cooperatively impair mitochondria in primary neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Truncated tau at D421 is associated with neurodegeneration and tangle formation in the brain of Alzheimer transgenic models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase-cleaved tau expression induces mitochondrial dysfunction in immortalized cortical neurons: implications for the pathogenesis of Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Multiple faces of dynamin-related protein 1 and its role in Alzheimer's disease pathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Reduced dynamin-related protein 1 protects against phosphorylated Tau-induced mitochondrial dysfunction and synaptic damage in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial dysfunction: an early event in Alzheimer pathology accumulates with age in AD transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Defects in mitochondrial dynamics and metabolomic signatures of evolving energetic stress in mouse models of familial Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial Dysfunction Contributes to the Pathogenesis of Alzheimer's Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Phosphorylated tau potentiates Aβ-induced mitochondrial damage in mature neurons.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Proteomic and functional analyses reveal a mitochondrial dysfunction in P301L tau transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Amyloid-β annular protofibrils evade fibrillar fate in Alzheimer disease brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Site-specific phosphorylation and caspase cleavage differentially impact tau-microtubule interactions and tau aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Immortalized cortical neurons expressing caspase-cleaved tau are sensitized to endoplasmic reticulum stress induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial fragmentation in neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Tau is essential to beta -amyloid-induced neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Tau facilitates Aβ-induced loss of mitochondrial membrane potential independent of cytosolic calcium fluxes in mouse cortical neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mechanisms of tau and Aβ-induced excitotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Tau reduction prevents Aβ-induced axonal transport deficits by blocking activation of GSK3β.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Soluble oligomers of the amyloid beta-protein impair synaptic plasticity and behavior

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Synaptic mitochondria are critical for mobilization of reserve pool vesicles at Drosophila neuromuscular junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondria at the synapse

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial free Ca²⁺ levels and their effects on energy metabolism in Drosophila motor nerve terminals

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Activity-driven local ATP synthesis is required for synaptic function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondria modulate Ca2+-dependent glutamate release from rat cortical astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial fusion protects against neurodegeneration in the cerebellum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Mitochondrial division ensures the survival of postmitotic neurons by suppressing oxidative damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

OPA1 loss of function affects in vitro neuronal maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Opa1 is essential for retinal ganglion cell synaptic architecture and connectivity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Loss of OPA1 disturbs cellular calcium homeostasis and sensitizes for excitotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Accumulation of aspartic acid421- and glutamic acid391-cleaved tau in neurofibrillary tangles correlates with progression in Alzheimer disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Tau truncation during neurofibrillary tangle evolution in Alzheimer's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase-cleaved tau exhibits rapid memory impairment associated with tau oligomers in a transgenic mouse model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Co-expression of truncated and full-length tau induces severe neurotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Dynamin-like protein 1 reduction underlies mitochondrial morphology and distribution abnormalities in fibroblasts from sporadic Alzheimer's disease patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Impaired balance of mitochondrial fission and fusion in Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

OPA1 controls apoptotic cristae remodeling independently from mitochondrial fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

The OPA1-dependent mitochondrial cristae remodeling pathway controls atrophic, apoptotic, and ischemic tissue damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Caspase activation precedes and leads to tangles

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

Behavioral deficit, oxidative stress, and mitochondrial dysfunction precede tau pathology in P301S transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-017-0385-X

The role of tau kinases in Alzheimer's disease

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28084594

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12035-017-0385-X

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28084594%20AND%20SRC:MED&resulttype=core&format=json

9 April 2020

1 reference