(Q50283881)

1 March 2018

title

Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo. (English)

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4

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Adria Giacca

9

object named as

Adria Giacca

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1 March 2018

author name string

Sandra Pereira

1

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Edward Park

2

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Jessy Moore

3

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Danna M Breen

5

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Andrei I Oprescu

6

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Ashraf Nahle

7

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Denise Kwan

8

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Evangelia Tsiani

10

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publication date

10 July 2015

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1 March 2018

Applied Physiology, Nutrition, and Metabolism

published in

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volume

40

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issue

11

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1 March 2018

page(s)

1129-1136

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Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.

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Resveratrol ameliorates diabetes-related metabolic changes via activation of AMP-activated protein kinase and its downstream targets in db/db mice.

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Resveratrol blocks interleukin-1beta-induced activation of the nuclear transcription factor NF-kappaB, inhibits proliferation, causes S-phase arrest, and induces apoptosis of acute myeloid leukemia cells

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Resveratrol improves adipose insulin signaling and reduces the inflammatory response in adipose tissue of rhesus monkeys on high-fat, high-sugar diet.

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Hydrogen peroxide activates IkappaB kinases through phosphorylation of serine residues in the activation loops

21 January 2018

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Pharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in rats

21 January 2018

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Differential regulation of insulin receptor substrates-1 and -2 (IRS-1 and IRS-2) and phosphatidylinositol 3-kinase isoforms in liver and muscle of the obese diabetic (ob/ob) mouse

21 January 2018

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PKC-theta knockout mice are protected from fat-induced insulin resistance

21 January 2018

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Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

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Free fatty acids increase basal hepatic glucose production and induce hepatic insulin resistance at different sites

21 January 2018

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21 January 2018

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21 January 2018

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Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance

21 January 2018

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Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes

21 January 2018

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Resveratrol induces pro-oxidant effects and time-dependent resistance to cytotoxicity in activated hepatic stellate cells.

21 January 2018

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Resveratrol stimulates glucose transport in C2C12 myotubes by activating AMP-activated protein kinase

21 January 2018

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Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo

21 January 2018

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Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation

21 January 2018

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FFA-induced hepatic insulin resistance in vivo is mediated by PKCδ, NADPH oxidase, and oxidative stress

21 January 2018

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High-dose resveratrol supplementation in obese men: an investigator-initiated, randomized, placebo-controlled clinical trial of substrate metabolism, insulin sensitivity, and body composition.

21 January 2018

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SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2

21 January 2018

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Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance

21 January 2018

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Fatty acid-induced insulin resistance in L6 myotubes is prevented by inhibition of activation and nuclear localization of nuclear factor kappa B

21 January 2018

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Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats

21 January 2018

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SIRT1 improves insulin sensitivity under insulin-resistant conditions by repressing PTP1B

21 January 2018

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Calorie Restriction-like Effects of 30 Days of Resveratrol Supplementation on Energy Metabolism and Metabolic Profile in Obese Humans

21 January 2018

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Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms

21 January 2018

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AMP-activated protein kinase-deficient mice are resistant to the metabolic effects of resveratrol

21 January 2018

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Sirtuin regulates cigarette smoke-induced proinflammatory mediator release via RelA/p65 NF-kappaB in macrophages in vitro and in rat lungs in vivo: implications for chronic inflammation and aging

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FAPNM-2015-0075

Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FAPNM-2015-0075

Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FAPNM-2015-0075

Naringenin, a citrus flavonoid, increases muscle cell glucose uptake via AMPK.

21 January 2018

1 reference

https://api.crossref.org/works/10.1139%2FAPNM-2015-0075

21 January 2018

Identifiers

DOI

10.1139/APNM-2015-0075

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1 March 2018

PubMed ID

26455923

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1 March 2018