(Q50288784)

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Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3

An instance of the biological reaction in Homo sapiens with Reactome ID (R-HSA-5655235)

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8 July 2022

Signaling by FGFR4 in disease

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8 July 2022

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8 July 2022

https://identifiers.org/reactome:R-HSA-5655235

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Activated FGFR4 mutants:p-FRS2:GRB2:GAB1:PI3K [plasma membrane]

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8 July 2022

1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate(5-)

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8 July 2022

1-phosphatidyl-1D-myo-inositol 3,4,5-trisphosphate(7-)

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8 July 2022

The t(8;22) in chronic myeloid leukemia fuses BCR to FGFR1: transforming activity and specific inhibition of FGFR1 fusion proteins

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8 July 2022

AZD2171 shows potent antitumor activity against gastric cancer over-expressing fibroblast growth factor receptor 2/keratinocyte growth factor receptor

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8 July 2022

PKC412 inhibits the zinc finger 198-fibroblast growth factor receptor 1 fusion tyrosine kinase and is active in treatment of stem cell myeloproliferative disorder

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8 July 2022

The phosphotyrosine phosphatase SHP2 is a critical mediator of transformation induced by the oncogenic fibroblast growth factor receptor 3

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8 July 2022

FGFR2-amplified gastric cancer cell lines require FGFR2 and Erbb3 signaling for growth and survival

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8 July 2022

8p12 stem cell myeloproliferative disorder: the FOP-fibroblast growth factor receptor 1 fusion protein of the t(6;8) translocation induces cell survival mediated by mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt/mTOR pathways

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8 July 2022

Inhibition of activated fibroblast growth factor receptor 2 in endometrial cancer cells induces cell death despite PTEN abrogation

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8 July 2022

Identifiers

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8 July 2022

(Q50288784)

Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3

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