(Q50318912)

3 March 2018

title

A Genome-wide CRISPR Death Screen Identifies Genes Essential for Oxidative Phosphorylation. (English)

1 reference

3 March 2018

RNA pseudouridine synthase D3

main subject

CRISPR

0 references

1 reference

Neugrin, neurite outgrowth associated

1 reference

RCC1 like

1 reference

OPA1 mitochondrial dynamin like GTPase

1 reference

FAST kinase domains 2

1 reference

TruB pseudouridine synthase family member 2

1 reference

RNA pseudouridine synthase D4

1 reference

positive regulation of mitochondrial translation

1 reference

1 reference

6

David E Root

1 reference

3 March 2018

John G Doench

5

object named as

John G Doench

1 reference

3 March 2018

Sarah E Calvo

3

object named as

Sarah E Calvo

1 reference

3 March 2018

Vamsi Mootha

7

object named as

Vamsi K Mootha

1 reference

3 March 2018

author name string

Jason D Arroyo

1

1 reference

3 March 2018

Alexis A Jourdain

2

1 reference

3 March 2018

Carmine A Ballarano

4

1 reference

3 March 2018

publication date

9 September 2016

1 reference

3 March 2018

published in

Cell Metabolism

1 reference

3 March 2018

volume

24

1 reference

3 March 2018

issue

6

1 reference

3 March 2018

page(s)

875-885

1 reference

3 March 2018

Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9.

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Intra-mitochondrial Methylation Deficiency Due to Mutations in SLC25A26

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

MitoCarta2.0: an updated inventory of mammalian mitochondrial proteins

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

FASTKD2 is an RNA-binding protein required for mitochondrial RNA processing and translation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Metformin inhibits mitochondrial complex I of cancer cells to reduce tumorigenesis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Broad metabolic sensitivity profiling of a prototrophic yeast deletion collection

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

New treatments for mitochondrial disease-no time to drop our standards

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mitochondrial disorders as windows into an ancient organelle

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Insights into RNA biology from an atlas of mammalian mRNA-binding proteins

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mitochondria: in sickness and in health

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mitochondrial disorders caused by mutations in respiratory chain assembly factors

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

A genome-wide shRNA screen for new OxPhos related genes

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Nutrient-sensitized screening for drugs that shift energy metabolism from mitochondrial respiration to glycolysis

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Highly parallel identification of essential genes in cancer cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

FASTKD2 nonsense mutation in an infantile mitochondrial encephalomyopathy associated with cytochrome c oxidase deficiency

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

A mitochondrial protein compendium elucidates complex I disease biology

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

In vivo and in organello analyses of mitochondrial translation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Systematic screen for human disease genes in yeast

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Role of AMP-activated protein kinase in mechanism of metformin action

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Two novel genes, human neugrin and mouse m-neugrin, are upregulated with neuronal differentiation in neuroblastoma cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mapping to nucleotide resolution of pseudouridine residues in large subunit ribosomal RNAs from representative eukaryotes, prokaryotes, archaebacteria, mitochondria and chloroplasts

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Human cells lacking mtDNA: repopulation with exogenous mitochondria by complementation

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Nonviability of cells with oxidative defects in galactose medium: a screening test for affected patient fibroblasts

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Evidence that glutamine, not sugar, is the major energy source for cultured HeLa cells

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Use of whole-exome sequencing to determine the genetic basis of multiple mitochondrial respiratory chain complex deficiencies.

22 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Defective NDUFA9 as a novel cause of neonatally fatal complex I disease

14 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5474757

Mitochondrial DNA in aging and disease

14 August 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27667664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CMET.2016.08.017

1 reference

3 March 2018

PMC publication ID

5474757

1 reference

3 March 2018

PubMed publication ID

27667664

1 reference

3 March 2018