(Q50335895)

English

STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production.

scientific article published on 21 October 2012

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

STAT1 activation by venous malformations mutant Tie2-R849W antagonizes VEGF-A-mediated angiogenic response partly via reduced bFGF production. (English)

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

author name string

Yi-Hsien Huang

1

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

Ming-Ping Wu

2

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

Shin-Chen Pan

3

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

Wu-Chou Su

4

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

Yi-Wen Chen

5

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

Li-Wha Wu

6

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

publication date

21 October 2012

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

16

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

1

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

207-222

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

https://scigraph.springernature.com/pub.10.1007/s10456-012-9313-x

0 references

Angiogenesis in embryonic development--a review

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Angiogenesis: now and then.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Vascular-specific growth factors and blood vessel formation

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Retinoic acid controls blood vessel formation by modulating endothelial and mural cell interaction via suppression of Tie2 signaling in vascular progenitor cells

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Molecular mechanisms of blood vessel growth

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Requisite role of angiopoietin-1, a ligand for the TIE2 receptor, during embryonic angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Angiopoietin and Tie signaling pathways in vascular development

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Vascular dysmorphogenesis caused by an activating mutation in the receptor tyrosine kinase TIE2

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Somatic mutations in angiopoietin receptor gene TEK cause solitary and multiple sporadic venous malformations

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Hereditary cutaneomucosal venous malformations are caused by TIE2 mutations with widely variable hyper-phosphorylating effects

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Functional analysis of a mutant form of the receptor tyrosine kinase Tie2 causing venous malformations.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Endothelial receptor tyrosine kinases activate the STAT signaling pathway: mutant Tie-2 causing venous malformations signals a distinct STAT activation response

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Tie2-R849W mutant in venous malformations chronically activates a functional STAT1 to modulate gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

STAT1 and STAT3 as intracellular regulators of vascular remodeling

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Visfatin through STAT3 activation enhances IL-6 expression that promotes endothelial angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Loss of protein inhibitors of activated STAT-3 expression in glioblastoma multiforme tumors: implications for STAT-3 activation and gene expression

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Activation of stat3 in human melanoma promotes brain metastasis.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Isolation and culture of arterial smooth muscle cells from human placenta

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

STAT1-induced apoptosis is mediated by caspases 2, 3, and 7.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Angiopoietin-1 and its receptor Tie-2 participate in the regulation of capillary-like tubule formation and survival of endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Endothelial cells and VEGF in vascular development

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Nuclear translocation of phosphorylated STAT3 is essential for vascular endothelial growth factor-induced human dermal microvascular endothelial cell migration and tube formation

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

STAT3: a critical transcription activator in angiogenesis.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Signal transducer and activator of transcription 1 activation in endothelial cells is a negative regulator of angiogenesis

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Nox1 mediates basic fibroblast growth factor-induced migration of vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

The molecular balance between receptor tyrosine kinases Tie1 and Tie2 is dynamically controlled by VEGF and TNFα and regulates angiopoietin signalling

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Role of STAT-1 and STAT-3 in ischaemia/reperfusion injury.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Opposing actions of STAT-1 and STAT-3.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Alternative activation of STAT1 and STAT3 in response to interferon-gamma

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Mutational switch of an IL-6 response to an interferon-gamma-like response

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Hypoxic induction of an HIF-1alpha-dependent bFGF autocrine loop drives angiogenesis in human endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

bFGF and LIF signaling activates STAT3 in proliferating myoblasts.

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

VEGF regulates FGF-2 and TGF-beta1 expression in injury endothelial cells and mediates smooth muscle cells proliferation and migration

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Vascular endothelial growth factor increases the migration and proliferation of smooth muscle cells through the mediation of growth factors released by endothelial cells

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Molecular regulation of vessel maturation

1 reference

https://api.crossref.org/works/10.1007%2FS10456-012-9313-X

21 January 2018

Identifiers

10.1007/S10456-012-9313-X

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

5 March 2018

http://europepmc.org/abstract/MED/23086340

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q50335895&oldid=1166579374"